sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4e8w | IHA | D-beta-D-heptose 7-phosphate kinase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4e8w | IHA | D-beta-D-heptose 7-phosphate kinase | / | 1.000 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.589 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.518 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.517 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.506 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.501 | |
| 2i5b | ADP | Pyridoxine kinase | / | 0.493 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.492 | |
| 2r43 | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.490 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.488 | |
| 5c3z | ACP | Ribokinase | / | 0.486 | |
| 1gqt | ACP | Ribokinase | / | 0.485 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.482 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.482 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.480 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.480 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.480 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.480 | |
| 2pvy | ACP | Fibroblast growth factor receptor 2 | / | 0.477 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.476 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.474 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.473 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.473 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.472 | |
| 2d4e | NAD | 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831] | / | 0.472 | |
| 1d4j | MSC | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.471 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.470 | |
| 3lki | ATP | Fructokinase | / | 0.469 | |
| 2yyy | NAP | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 | 0.468 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.468 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.467 | |
| 3vfa | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.466 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.466 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.466 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.465 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.465 | |
| 5c3y | AN2 | Ribokinase | / | 0.465 | |
| 1idb | 0DO | Gag-Pol polyprotein | / | 0.464 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.463 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.463 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.462 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.461 | |
| 2yyu | C5P | Orotidine 5'-phosphate decarboxylase | / | 0.461 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 1d4h | BEH | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.460 | |
| 1sgu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.460 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.459 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.459 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.459 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.459 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.459 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.459 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1msn | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 3anx | MTA | Polyamine aminopropyltransferase | / | 0.458 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.458 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.458 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.458 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.457 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.457 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 4dqh | 017 | Gag-Pol polyprotein | / | 0.457 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.457 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.456 | |
| 1c6y | MK1 | Protease | / | 0.456 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.456 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.456 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.456 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.456 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2bpv | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2cdu | FAD | NADH oxidase | / | 0.455 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.455 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 3so9 | 017 | Pol protein | / | 0.455 | |
| 5a3b | APR | SIR2 family protein | / | 0.455 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.454 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.454 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.453 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.453 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.452 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.452 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.452 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.452 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.452 | |
| 4iaz | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.452 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.452 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.451 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.451 | |
| 1wbk | 568 | Pol protein | / | 0.451 | |
| 2b60 | RIT | Pol polyprotein | / | 0.451 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.451 | |
| 3a3g | DLZ | Lumazine protein | / | 0.451 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.451 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.451 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.451 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.451 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 1ec3 | MS3 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2i4v | DJR | V-1 protease | / | 0.450 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.450 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.450 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.450 | |
| 3oy4 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3sa7 | 55A | Protease | / | 0.450 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.450 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.449 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.449 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2nu9 | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.449 | |
| 2r3t | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.449 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.449 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.449 | |
| 4cfd | S8Y | Integrase | / | 0.449 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.449 | |
| 4fxf | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.449 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.448 | |
| 3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.448 | |
| 3o9a | K14 | Pol polyprotein | / | 0.448 | |
| 3qa2 | XNA | Ketohexokinase | / | 0.448 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.448 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 5byu | COA | Thioesterase | / | 0.448 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.447 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.447 | |
| 1pro | A88 | Gag-Pol polyprotein | / | 0.447 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.447 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.447 | |
| 2bb9 | AKC | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3pll | F06 | Endothiapepsin | 3.4.23.22 | 0.447 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.447 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.446 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.446 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.446 | |
| 2vbq | BSJ | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.446 | |
| 3fl9 | TOP | Dihydrofolate reductase | / | 0.446 | |
| 3kdd | JZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 4lj6 | ACP | Chaperone protein ClpB | / | 0.446 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.445 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.445 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.445 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 3eya | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.445 | |
| 3nbv | ANP | Ketohexokinase | / | 0.445 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.445 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.445 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.445 | |
| 4pd6 | URI | Nucleoside permease | / | 0.445 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1hiv | 1ZK | Gag-Pol polyprotein | / | 0.444 | |
| 1lqu | NDP | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.444 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.444 | |
| 1yt9 | OIS | Gag-Pol polyprotein | / | 0.444 | |
| 1ztf | XYA | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.444 | |
| 2ilu | NDP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.444 | |
| 2ixa | NAD | Alpha-N-acetylgalactosaminidase | 3.2.1.49 | 0.444 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.444 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.444 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.444 | |
| 3i6o | GR6 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.444 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 2hs2 | 017 | Protease | / | 0.443 | |
| 2qhc | AB1 | Protease | / | 0.443 | |
| 2r3w | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.443 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.443 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4cgj | NZL | Integrase | / | 0.443 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.443 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.443 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.443 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.443 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.443 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.442 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.442 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1qbs | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.442 | |
| 1w5s | ADP | ORC1-type DNA replication protein 2 | / | 0.442 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.442 | |
| 2i4w | KGQ | Protease | / | 0.442 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.442 | |
| 2wmr | ZYR | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.442 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.442 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.442 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 3nu3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.442 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 4ftn | 2HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 5a3c | NAD | SIR2 family protein | / | 0.442 | |
| 5j3w | FMN | Sensory box protein | / | 0.442 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1fdo | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.441 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.441 | |
| 1mez | GDP | Adenylosuccinate synthetase isozyme 1 | / | 0.441 | |
| 1tcx | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2qd8 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2wzg | UPG | Uncharacterized protein | / | 0.441 | |
| 3bvb | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 3kfr | 3TL | Gag-Pol polyprotein | / | 0.441 | |
| 3sa9 | A68 | Protease | / | 0.441 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.441 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.441 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.441 | |
| 4cvl | ACP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.441 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4n6b | COA | Uncharacterized protein | / | 0.441 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.441 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.441 | |
| 1eby | BEB | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1izh | Q50 | Protease | / | 0.440 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.440 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.440 | |
| 1sb8 | UD2 | WbpP | / | 0.440 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 2avs | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 2q55 | MU0 | Protease | / | 0.440 | |
| 2qhz | MZ2 | Gag-Pol polyprotein | / | 0.440 | |
| 2uy0 | HV1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2wkz | 5AH | Gag-Pol polyprotein | / | 0.440 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.440 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 3edj | BCD | Cyclomaltodextrinase | / | 0.440 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.440 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 4ces | NFW | Integrase | / | 0.440 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.440 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.440 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 9hvp | 0E9 | Gag-Pol polyprotein | / | 0.440 |