sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 1.000 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.642 | |
| 3o8h | O8H | HTH-type transcriptional regulator EthR | / | 0.636 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.631 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.628 | |
| 3g1m | RF3 | HTH-type transcriptional regulator EthR | / | 0.574 | |
| 3q0v | LL4 | HTH-type transcriptional regulator EthR | / | 0.572 | |
| 3g1l | RF2 | HTH-type transcriptional regulator EthR | / | 0.549 | |
| 3g1o | RF1 | HTH-type transcriptional regulator EthR | / | 0.544 | |
| 3sfi | 3SF | HTH-type transcriptional regulator EthR | / | 0.541 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.504 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.498 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.495 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.493 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.493 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.491 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.489 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.489 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.489 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.487 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.486 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.485 | |
| 2xvv | 9DN | Serum albumin | / | 0.485 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.485 | |
| 2pcg | SAH | Diphthine synthase | / | 0.484 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.484 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.483 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.483 | |
| 1eio | GCH | Gastrotropin | / | 0.482 | |
| 2emu | SAH | Diphthine synthase | / | 0.482 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 2z6r | SAH | Diphthine synthase | / | 0.482 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.482 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.482 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.481 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.481 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.481 | |
| 2e16 | SAH | Diphthine synthase | / | 0.480 | |
| 3b9l | AZZ | Serum albumin | / | 0.480 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.480 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.480 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.479 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.478 | |
| 3ele | PLP | Aminotransferase | / | 0.478 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.478 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.478 | |
| 2ele | SAH | Diphthine synthase | / | 0.477 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.477 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.477 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.477 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.477 | |
| 1g28 | FMN | PHY3 | / | 0.476 | |
| 2eka | SAH | Diphthine synthase | / | 0.476 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.476 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.476 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.476 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.476 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.475 | |
| 2bxq | IMN | Serum albumin | / | 0.475 | |
| 4boe | CLR | Japanin | / | 0.475 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.475 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.475 | |
| 2p6d | SAH | Diphthine synthase | / | 0.474 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.474 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.474 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.474 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.474 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.474 | |
| 4lb2 | DM5 | Serum albumin | / | 0.474 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.474 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.473 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.473 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.473 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.473 | |
| 4v2g | CTC | Tetracycline repressor protein class D | / | 0.473 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.472 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2emr | SAH | Diphthine synthase | / | 0.471 | |
| 2xvw | 9NR | Serum albumin | / | 0.471 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.471 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 4phl | PIL | Phosphodiesterase | / | 0.471 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.470 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.469 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.469 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.469 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
| 2vle | DZN | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.469 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.469 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.469 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.469 | |
| 2e08 | SAH | Diphthine synthase | / | 0.468 | |
| 2pch | SAH | Diphthine synthase | / | 0.468 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.468 | |
| 3kej | 3EJ | Collagenase 3 | 3.4.24 | 0.468 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.468 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.468 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.467 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.467 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.467 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.467 | |
| 4ha6 | PXM | Pyridoxine 4-oxidase | / | 0.467 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.467 | |
| 1ppj | ANY | Cytochrome b | / | 0.466 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.466 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.466 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.466 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.466 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.466 | |
| 2v7q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.465 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.464 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 4c2y | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.464 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.464 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.464 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.463 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.463 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.463 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.463 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.463 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.462 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.462 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 2ejz | SAH | Diphthine synthase | / | 0.462 | |
| 2ow9 | SP6 | Collagenase 3 | 3.4.24 | 0.462 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.462 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.462 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.462 | |
| 4ac0 | MIY | Tetracycline repressor protein class B from transposon Tn10 | / | 0.462 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.462 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.461 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.461 | |
| 2e83 | FMN | FMN-binding protein | / | 0.461 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.461 | |
| 4kxj | P34 | Nucleoprotein | / | 0.461 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 2dsg | SAH | Diphthine synthase | / | 0.460 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.460 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.460 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.460 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.460 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.460 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.460 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.459 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 2b5j | 3AC | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2nnl | ERD | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.459 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.459 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.459 | |
| 3f4b | TCL | Enoyl-acyl carrier protein reductase | / | 0.459 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.459 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 3myk | BIT | Myosin-2 heavy chain | / | 0.459 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.459 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.459 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.459 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.459 | |
| 5dg3 | U21 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | / | 0.459 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.459 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.458 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.458 | |
| 3fmz | 2T1 | Retinol-binding protein 4 | / | 0.458 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.458 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.458 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.458 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.458 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.458 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.458 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.457 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.457 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.457 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.457 | |
| 2wge | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.457 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.457 | |
| 3rbq | GLY_ALA_GLY_DAO | Protein unc-119 homolog A | / | 0.457 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.457 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.457 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.457 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.457 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.457 | |
| 4rw6 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.457 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.456 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.456 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.456 | |
| 2e8h | SAH | Diphthine synthase | / | 0.456 | |
| 2pcm | SAH | Diphthine synthase | / | 0.456 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 3mde | CO8 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.456 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.456 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.456 | |
| 4gue | QCT | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.456 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.456 | |
| 4okt | 198 | Androgen receptor | / | 0.456 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.456 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.455 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.455 | |
| 1xud | PB4 | Collagenase 3 | 3.4.24 | 0.455 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.455 | |
| 2huv | SAH | Diphthine synthase | / | 0.455 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.455 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.455 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.455 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.455 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.455 | |
| 4bz8 | J38 | Histone deacetylase | / | 0.455 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.455 | |
| 4ie5 | MD6 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.455 | |
| 1njf | AGS | DNA polymerase III subunit tau | 2.7.7.7 | 0.454 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.454 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.454 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2egb | SAH | Diphthine synthase | / | 0.454 | |
| 2ic3 | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 2o2s | TCL | Enoyl-acyl carrier reductase | / | 0.454 | |
| 3abi | NAD | Uncharacterized protein | / | 0.454 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.454 | |
| 3dol | GWI | Pol protein | / | 0.454 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.454 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.454 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.454 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 4ug9 | 1EW | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.454 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.454 | |
| 1e7a | PFL | Serum albumin | / | 0.453 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.453 | |
| 2egl | SAH | Diphthine synthase | / | 0.453 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.453 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.453 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.453 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.453 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.453 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.453 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.453 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.453 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.453 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.453 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.453 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.452 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.452 | |
| 2kce | D16 | Thymidylate synthase | / | 0.452 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.452 | |
| 3gts | D3M | DdmC | / | 0.452 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.452 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.452 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.452 | |
| 1c8t | TR1 | Stromelysin-1 | 3.4.24.17 | 0.451 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.451 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.451 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.451 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.451 | |
| 2p5f | SAH | Diphthine synthase | / | 0.451 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.451 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.451 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.451 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.451 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.450 | |
| 1hk5 | T44 | Serum albumin | / | 0.450 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.450 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.450 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.450 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.450 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2mm3 | CHO | Gastrotropin | / | 0.450 | |
| 2ogi | GDP | Uncharacterized protein | / | 0.450 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.450 | |
| 3nj8 | NJ8 | Enoyl-acyl carrier reductase | / | 0.450 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.450 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4e0i | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.450 | |
| 4iah | 1DX | Alr2278 protein | / | 0.450 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.449 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.449 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.449 | |
| 2dxv | SAH | Diphthine synthase | / | 0.449 | |
| 2p2j | PRX | Acetyl-coenzyme A synthetase | / | 0.449 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3c1o | NAP | Eugenol synthase | / | 0.449 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.449 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.449 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.449 | |
| 4hdr | DMD | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | / | 0.449 | |
| 4hdr | DMD | ArsB | / | 0.449 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.449 | |
| 5es7 | FON | Linear gramicidin synthase subunit A | / | 0.449 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.448 | |
| 1m8h | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.448 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2e8q | SAH | Diphthine synthase | / | 0.448 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.448 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.448 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 3g5m | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 3qly | 55V | Uncharacterized protein | / | 0.448 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.448 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.448 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.448 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.448 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.448 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.447 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.447 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.447 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.447 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.447 | |
| 2e15 | SAH | Diphthine synthase | / | 0.447 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.447 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2zju | IM4 | Acetylcholine-binding protein | / | 0.447 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.447 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.447 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.447 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.447 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.447 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.447 | |
| 5cdt | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.447 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.446 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.446 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.446 | |
| 2dxw | SAH | Diphthine synthase | / | 0.446 | |
| 2egs | SAH | Diphthine synthase | / | 0.446 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.446 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2ozr | GG1 | Collagenase 3 | 3.4.24 | 0.446 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.446 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.446 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.446 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.446 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.446 | |
| 3eek | 53S | Uncharacterized protein | / | 0.446 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.446 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.446 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.446 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.446 | |
| 3vhm | NPK | Avidin | / | 0.446 | |
| 4a4v | YFD | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4e0h | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.446 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.446 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.446 | |
| 1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.445 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.445 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.445 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.445 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.445 | |
| 1nv9 | SAH | Release factor glutamine methyltransferase | 2.1.1.297 | 0.445 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.445 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.445 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.445 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.445 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.445 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.445 | |
| 3bnk | FMN | Flavoredoxin | / | 0.445 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.445 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.445 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.445 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.445 | |
| 4ceq | QCH | Integrase | / | 0.445 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.445 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.445 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.444 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.444 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.444 | |
| 1pt8 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.444 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1vce | SAH | Diphthine synthase | / | 0.444 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.444 | |
| 2hut | SAH | Diphthine synthase | / | 0.444 | |
| 2iyg | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.444 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.444 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.444 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.444 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.444 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.444 | |
| 3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 4bbh | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.444 | |
| 4ovi | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.444 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.444 | |
| 4y0k | NAP | AntE | / | 0.444 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.444 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.443 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.443 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.443 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.443 | |
| 2el3 | SAH | Diphthine synthase | / | 0.443 | |
| 2owv | SAH | Diphthine synthase | / | 0.443 | |
| 2pck | SAH | Diphthine synthase | / | 0.443 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.443 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.443 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.443 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.443 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.443 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.443 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4msg | 2C6 | Tankyrase-1 | 2.4.2.30 | 0.443 | |
| 4okx | 198 | Androgen receptor | / | 0.443 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.443 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.443 | |
| 1jf0 | CZH | Obelin | / | 0.442 | |
| 1jut | LYD | Thymidylate synthase | / | 0.442 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.442 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 1rt7 | UC4 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.442 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.442 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.442 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.442 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 2o2y | TCL | Enoyl-ACP reductase | / | 0.442 | |
| 2uyw | BTN | Avd protein | / | 0.442 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.442 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.442 | |
| 3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.442 | |
| 3inl | BXB | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.442 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.442 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.442 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.442 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 4gqi | M49 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.442 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.442 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.442 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.442 | |
| 1a80 | NDP | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.441 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.441 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.441 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.441 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.441 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.441 | |
| 1xur | PB5 | Collagenase 3 | 3.4.24 | 0.441 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.441 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.441 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.441 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.441 | |
| 2pin | 4HY | Thyroid hormone receptor beta | / | 0.441 | |
| 2vcw | ZZA | Hematopoietic prostaglandin D synthase | / | 0.441 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3fne | 8PC | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.441 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.441 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.441 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.441 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.441 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.441 | |
| 4h0u | UMP | Thymidylate synthase | / | 0.441 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.441 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 4ykg | NAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.441 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.441 | |
| 5c3j | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.441 | |
| 5c3j | UQ1 | Succinate dehydrogenase cytochrome b560 | / | 0.441 | |
| 5doz | NDP | JamJ | / | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1m2z | DEX | Glucocorticoid receptor | / | 0.440 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1sst | COA | Serine acetyltransferase | 2.3.1.30 | 0.440 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.440 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.440 | |
| 2eld | SAH | Diphthine synthase | / | 0.440 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.440 | |
| 2p9d | SAH | Diphthine synthase | / | 0.440 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.440 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.440 | |
| 2x23 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3abx | RCB | Glucanase | / | 0.440 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.440 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.440 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.440 | |
| 4ey2 | 0RM | Metallo-beta-lactamase type 2 | / | 0.440 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.440 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.440 | |
| 4l8u | 9AZ | Serum albumin | / | 0.440 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 | |
| 5cdg | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 5dp2 | NAP | CurF | / | 0.440 | |
| 5ifi | PRX | Acetyl-coenzyme A synthetase | / | 0.440 |