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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4dvi2IWTankyrase-12.4.2.30

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4dvi2IWTankyrase-12.4.2.301.000
4n4v2GYTankyrase-12.4.2.300.538
4bfpSWYTankyrase-22.4.2.300.533
4i9i1DYTankyrase-12.4.2.300.523
4msg2C6Tankyrase-12.4.2.300.493
4n4t2GVTankyrase-12.4.2.300.482
4mt92D6Tankyrase-12.4.2.300.478
3u9y09LTankyrase-22.4.2.300.469
4hyf1AKTankyrase-22.4.2.300.466
4bj9UHBTankyrase-22.4.2.300.465
4li71XPTankyrase-12.4.2.300.465
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442