sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4dvg | GSP | Rho family GTPase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4dvg | GSP | Rho family GTPase | / | 1.000 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.567 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.546 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.537 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.529 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.521 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.517 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.516 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.515 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.507 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.501 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.500 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.498 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.495 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.488 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.488 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.481 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.481 | |
| 4e03 | ADP | Plasmid partitioning protein ParF | / | 0.477 | |
| 4dzz | ADP | Plasmid partitioning protein ParF | / | 0.475 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.472 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.470 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.466 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.465 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.462 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.457 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.456 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.453 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.451 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.451 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.451 | |
| 4mit | GTP | Rho-related protein racC | / | 0.448 | |
| 3ref | GDP | Rho family GTPase | / | 0.445 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.445 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.444 | |
| 4dlt | GNP | GTPase HRas | / | 0.443 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.441 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.441 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.440 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.440 |