sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4de5 | 0JD | Pantothenate synthetase | 6.3.2.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4de5 | 0JD | Pantothenate synthetase | 6.3.2.1 | 1.000 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.694 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.633 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.632 | |
| 3iob | A4D | Pantothenate synthetase | 6.3.2.1 | 0.622 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.613 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.591 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.573 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.570 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.565 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.562 | |
| 3coz | 54H | Pantothenate synthetase | 6.3.2.1 | 0.558 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.558 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.550 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.546 | |
| 1n2g | APC | Pantothenate synthetase | 6.3.2.1 | 0.535 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.532 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.529 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.526 | |
| 1n2e | APC | Pantothenate synthetase | 6.3.2.1 | 0.524 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.517 | |
| 1n2b | PAF | Pantothenate synthetase | 6.3.2.1 | 0.500 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.473 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.472 | |
| 1n1d | C2G | Glycerol-3-phosphate cytidylyltransferase | 2.7.7.39 | 0.457 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.455 | |
| 3zxi | TYA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.454 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.454 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.449 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.448 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.447 | |
| 3nzp | PLP | Arginine decarboxylase | / | 0.447 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.446 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.445 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.444 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.442 | |
| 3ts1 | TYA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.441 |