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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4dc0NDPPutative ketoacyl reductase1.3.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4dc0NDPPutative ketoacyl reductase1.3.11.000
1x7hNDPPutative ketoacyl reductase1.3.10.504
1x7gNAPPutative ketoacyl reductase1.3.10.492
4dbzNDPPutative ketoacyl reductase1.3.10.492
1w4zNAPPutative ketoacyl reductase1.3.10.480
3sjuNDPKeto reductase/0.464