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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.30

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.301.000
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.632
3vfqAR6Poly [ADP-ribose] polymerase 142.4.2.300.610
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.443
3d7kD7KBenzaldehyde lyase/0.442
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.441
3b70NAPEnoyl reductase LovC10.440