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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.233

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2331.000
4idgNADPutative UDP-glucose 4-epimerase/0.478
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.466
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.464
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.456
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.451
4fn4NADShort chain dehydrogenase/0.449
3ak4NADNADH-dependent quinuclidinone reductase/0.441
1zemNADXylitol dehydrogenase/0.440
3a4vNADNDP-sugar epimerase/0.440
4nbwNADShort-chain dehydrogenase/reductase SDR/0.440