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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4cidANPEH domain-containing protein 2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4cidANPEH domain-containing protein 2/1.000
3mjhGTPRas-related protein Rab-5A/0.478
1n6lGTPRas-related protein Rab-5A/0.477
1zbdGTPRas-related protein Rab-3A/0.475
3kkoGNPRas-related protein M-Ras/0.474
3oesGNPGTPase RhebL1/0.465
2fe4GDPRas-related protein Rab-6B/0.462
3ddcGNPGTPase HRas/0.462
5dhaGNPGTP-binding nuclear protein Ran/0.461
3v4fGNPGTPase HRas/0.460
2fg5GNPRas-related protein Rab-31/0.459
4nyiGNPGTPase HRas/0.457
1xtsGTPGTP-binding protein Rheb/0.454
1e96GTPRas-related C3 botulinum toxin substrate 1/0.453
1zd9GDPADP-ribosylation factor-like protein 8A/0.453
3wyfGTPGTP-binding nuclear protein/0.452
4l8gGDPGTPase KRas/0.451
3tgpGNPGTPase HRas/0.450
4rkfGNPRas-related protein Rab-3/0.450
3pitGNPRas-related protein M-Ras/0.449
3a6pGTPGTP-binding nuclear protein Ran/0.445
2rggGNPGTPase HRas/0.444
3oivGNPGTPase HRas/0.443
2rgeGNPGTPase HRas/0.442
3lbhGNPGTPase HRas/0.442
2rgcGNPGTPase HRas/0.441
1z2aGDPRas-related protein Rab-23/0.440