sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4cez | O3N | Integrase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3zsr | O3N | Integrase | / | 1.000 | |
| 4cez | O3N | Integrase | / | 1.000 | |
| 4ceo | G0T | Integrase | / | 0.682 | |
| 4ced | 9NS | Integrase | / | 0.673 | |
| 4cgg | K5Q | Integrase | / | 0.660 | |
| 3zt0 | ZT0 | Integrase | / | 0.652 | |
| 4cea | ZSW | Integrase | / | 0.648 | |
| 4cf8 | V7H | Integrase | / | 0.641 | |
| 4ceq | QCH | Integrase | / | 0.635 | |
| 3zsv | ZSV | Integrase | / | 0.630 | |
| 4ceb | ZSV | Integrase | / | 0.630 | |
| 4cfb | OM3 | Integrase | / | 0.626 | |
| 3zsw | ZSW | Integrase | / | 0.625 | |
| 4cjr | FYM | Integrase | / | 0.625 | |
| 4cig | X0P | Integrase | / | 0.622 | |
| 4ce9 | O3N | Integrase | / | 0.617 | |
| 4cer | VL4 | Integrase | / | 0.615 | |
| 4cif | JDX | Integrase | / | 0.602 | |
| 4cfa | WOP | Integrase | / | 0.600 | |
| 3zsq | O4N | Integrase | / | 0.598 | |
| 4cfc | 7NV | Integrase | / | 0.598 | |
| 4cgj | NZL | Integrase | / | 0.597 | |
| 4cj3 | E4F | Integrase | / | 0.597 | |
| 4cgd | 8P3 | Integrase | / | 0.593 | |
| 4ck1 | OM1 | Integrase | / | 0.593 | |
| 4ck2 | NVU | Integrase | / | 0.592 | |
| 4cef | D0T | Integrase | / | 0.590 | |
| 3zsy | OM3 | Integrase | / | 0.589 | |
| 4cjf | RVN | Integrase | / | 0.588 | |
| 4cgh | LOZ | Integrase | / | 0.587 | |
| 4cje | Q31 | Integrase | / | 0.584 | |
| 4chy | C5Q | Integrase | / | 0.582 | |
| 4cju | JNS | Integrase | / | 0.581 | |
| 4cjs | L0Y | Integrase | / | 0.580 | |
| 4cgi | NZL | Integrase | / | 0.578 | |
| 4cf0 | O5U | Integrase | / | 0.576 | |
| 3zsz | OM2 | Integrase | / | 0.575 | |
| 4cf2 | 3GM | Integrase | / | 0.575 | |
| 4cjp | 4D2 | Integrase | / | 0.572 | |
| 4cjq | VXO | Integrase | / | 0.570 | |
| 4cee | B0T | Integrase | / | 0.566 | |
| 3zcm | PX3 | Integrase | / | 0.564 | |
| 4cec | 2SS | Integrase | / | 0.563 | |
| 4cfd | S8Y | Integrase | / | 0.563 | |
| 4cjk | H39 | Integrase | / | 0.563 | |
| 4cf1 | IY7 | Integrase | / | 0.554 | |
| 3zt2 | ZT2 | Integrase | / | 0.547 | |
| 4cie | Y7N | Integrase | / | 0.546 | |
| 3zt3 | ZT4 | Integrase | / | 0.545 | |
| 4ck3 | K1T | Integrase | / | 0.544 | |
| 4ces | NFW | Integrase | / | 0.543 | |
| 4cj5 | 4VW | Integrase | / | 0.542 | |
| 3zsx | N44 | Integrase | / | 0.533 | |
| 4chq | CWU | Integrase | / | 0.525 | |
| 4cj4 | S3G | Integrase | / | 0.523 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.497 | |
| 3zt1 | OM1 | Integrase | / | 0.495 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.489 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.484 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.481 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.481 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.477 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.475 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.475 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.474 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.472 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.471 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.469 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.469 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.468 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.468 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.467 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.466 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3tw6 | ADP | Pyruvate carboxylase | / | 0.466 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.465 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.464 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.464 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.464 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.463 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.463 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.463 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.463 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.462 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.462 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.461 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.461 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.461 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.460 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.460 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.460 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.459 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3vfa | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.457 | |
| 2bxm | IMN | Serum albumin | / | 0.457 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.457 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 2ohv | NHL | Glutamate racemase | / | 0.456 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.456 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.456 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.456 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.456 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.455 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.455 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.455 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.455 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.454 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.454 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.453 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.453 | |
| 4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.453 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.452 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.452 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.452 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.452 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.452 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.451 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.451 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.451 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.451 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.451 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1qvn | FRI | Interleukin-2 | / | 0.450 | |
| 3a7j | ADP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.450 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.450 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.450 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.450 | |
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.449 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.449 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.449 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.449 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.449 | |
| 3zuy | TCH | Transporter | / | 0.449 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.449 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.449 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.449 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.449 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.448 | |
| 1met | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.448 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.448 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.448 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.448 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.448 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 5ax3 | 5ID | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.447 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.447 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.447 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.447 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.446 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.446 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.446 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.446 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.446 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.446 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.446 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.445 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3n6u | TSU | HTH-type transcriptional regulator TsaR | / | 0.445 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.445 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.445 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.445 | |
| 1cer | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.444 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.444 | |
| 1msn | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.444 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.444 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.444 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.444 | |
| 3r7e | X88 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.444 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.444 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.444 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.444 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.444 | |
| 1eio | GCH | Gastrotropin | / | 0.443 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.443 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.443 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.443 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.443 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.443 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.443 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 2xvu | 9DN | Serum albumin | / | 0.443 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.443 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.443 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3tnw | F18 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.443 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.443 | |
| 4d9t | 0JG | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.443 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.443 | |
| 4q1y | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.443 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.443 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.442 | |
| 1pw6 | FRB | Interleukin-2 | / | 0.442 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.442 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.442 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.442 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.442 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.442 | |
| 3so9 | 017 | Pol protein | / | 0.442 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4cgf | UJ6 | Integrase | / | 0.442 | |
| 4hxy | NDP | Plm1 | / | 0.442 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.441 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.441 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 2xnb | Y8L | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.441 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.441 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.441 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.441 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.441 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.441 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.441 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.441 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.441 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.441 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.441 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.441 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.441 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.441 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.440 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.440 | |
| 3eks | CY9 | Actin-5C | / | 0.440 | |
| 3q5d | GDP | Atlastin-1 | 3.6.5 | 0.440 | |
| 3sw4 | 18K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.440 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.440 |