Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4c5cATPD-alanine--D-alanine ligase B6.3.2.4

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4c5cATPD-alanine--D-alanine ligase B6.3.2.41.000
4c5bADPD-alanine--D-alanine ligase B6.3.2.40.604
5bpfADPD-alanine--D-alanine ligase/0.516
4z35ON9Lysophosphatidic acid receptor 1/0.486
4z34ON7Lysophosphatidic acid receptor 1/0.468
4g1y0VOVitamin D3 receptor A/0.460
1tduCB3Thymidylate synthase/0.458
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.457
1adfTADAlcohol dehydrogenase E chain1.1.1.10.455
3a8tATPAdenylate isopentenyltransferase/0.448
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.447
3r7cFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.445
2vceU2FUDP-glycosyltransferase 72B1/0.444
1nhtPGSAdenylosuccinate synthetase/0.443
2uxuNARHTH-type transcriptional regulator TtgR/0.443
2ykiYKIHeat shock protein HSP 90-alpha/0.443
4jlm1NNDeoxycytidine kinase2.7.1.740.443
2dbzNAPGlyoxylate reductase1.1.1.260.442
2q4bNAPUncharacterized protein At5g02240/0.442
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.442
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.441
4xznNAPAldo-keto reductase family 1 member B101.1.10.441
3jq3ADPLombricine kinase/0.440
4ehyADPTetraacyldisaccharide 4'-kinase/0.440
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.440