Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4bwa | N0B | Pyrrolysine--tRNA ligase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4bwa | N0B | Pyrrolysine--tRNA ligase | / | 1.000 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.517 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.510 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.506 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.503 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.502 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.497 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.495 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.495 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.492 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.491 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.491 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.490 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.490 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.488 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.488 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.485 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.484 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.483 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.483 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.482 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.480 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.478 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.478 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.477 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.477 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.477 | |
| 5d7p | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.477 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.476 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.475 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.475 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.475 | |
| 3v8t | 477 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.475 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.475 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.474 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.474 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.474 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.474 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.474 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.473 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.473 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.473 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.473 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.473 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.472 | |
| 3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.472 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.472 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.472 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.472 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.472 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.471 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.471 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.471 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.471 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.471 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 5fwg | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.471 | |
| 1v0o | INR | Cell division control protein 2 homolog | 2.7.11.22 | 0.470 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.470 | |
| 2qqf | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.470 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.470 | |
| 4mgi | CMP | Rap guanine nucleotide exchange factor 4 | / | 0.470 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.469 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.469 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.469 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 4h3z | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.469 | |
| 4hgt | 15G | Casein kinase I isoform delta | 2.7.11.1 | 0.469 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 5d7q | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.469 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.468 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.468 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.467 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.467 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.467 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.467 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.467 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.467 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3up3 | XCA | aceDAF-12 | / | 0.467 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.467 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.467 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.466 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.466 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 2xiy | XIY | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 3b9l | AZZ | Serum albumin | / | 0.466 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.466 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.466 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.466 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.465 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.465 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.465 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.464 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 2xng | A0H | Aurora kinase A | 2.7.11.1 | 0.464 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.464 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.464 | |
| 3wi6 | YRZ | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.464 | |
| 4gst | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.464 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.463 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.463 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.463 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 3qpv | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.463 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.463 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.463 | |
| 4lsl | 1YQ | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.462 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.462 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.462 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.462 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.462 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.462 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.462 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.462 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.462 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.461 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.461 | |
| 2bxm | IMN | Serum albumin | / | 0.461 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.461 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.461 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.461 | |
| 4iah | 1DX | Alr2278 protein | / | 0.461 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.461 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.460 | |
| 1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.460 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.460 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.460 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.460 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.460 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.460 | |
| 3zns | NU7 | Histone deacetylase 7 | 3.5.1.98 | 0.460 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.460 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.460 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.459 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.459 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.459 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.459 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.459 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.459 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.459 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.459 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.459 | |
| 4c68 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.459 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.459 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.459 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.458 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2bxq | IMN | Serum albumin | / | 0.458 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.458 | |
| 2puj | HPZ | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.458 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.458 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.458 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.458 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.458 | |
| 4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 | 0.458 | |
| 4nqm | Y1Z | Bromodomain-containing protein 4 | / | 0.458 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.458 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.458 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.457 | |
| 1cde | DZF | Phosphoribosylglycinamide formyltransferase | / | 0.457 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.457 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.457 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.457 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.457 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.457 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2mm3 | CHO | Gastrotropin | / | 0.457 | |
| 2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.457 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.457 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.456 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 2r64 | 740 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.456 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.456 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4afe | GGY | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.456 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.456 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.456 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.456 | |
| 4p68 | MTX | Dihydrofolate reductase | / | 0.456 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.455 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.455 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.455 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.455 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.455 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.455 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.455 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.455 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.455 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.455 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.455 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.455 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.454 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.454 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2jkq | VG8 | Focal adhesion kinase 1 | 2.7.10.2 | 0.454 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 2xvw | 9NR | Serum albumin | / | 0.454 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.454 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.454 | |
| 3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.454 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.454 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.454 | |
| 3qly | 55V | Uncharacterized protein | / | 0.454 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.454 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.454 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.454 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.454 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.453 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.453 | |
| 3fzr | 3JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.453 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3r0t | FU9 | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.453 | |
| 4c2u | ANP | DNA helicase | / | 0.453 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.453 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.453 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.453 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.453 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.453 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.453 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.452 | |
| 1jut | LYD | Thymidylate synthase | / | 0.452 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.452 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.452 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.452 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.452 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.452 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.452 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.452 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4eh7 | 0OO | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4ieb | ANP | Calmodulin-domain protein kinase 1 | / | 0.452 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.452 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 4ucn | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.452 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.451 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.451 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.451 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.451 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.451 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.451 | |
| 2vtn | LZ7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2ybo | SAH | Methyltransferase | / | 0.451 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.451 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3huc | G97 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.451 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.451 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.451 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 3zux | TCH | Transporter | / | 0.451 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.451 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.451 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.451 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.451 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.451 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.451 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4l2y | XXK | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.451 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.451 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.451 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.451 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 5cvc | PLP | Serine racemase | / | 0.451 | |
| 5dr2 | ATP | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.451 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.451 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.450 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 1mq0 | BRD | Cytidine deaminase | 3.5.4.5 | 0.450 | |
| 2acw | UPG | Glycosyltransferase | / | 0.450 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.450 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 2wsa | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.450 | |
| 3eej | 53R | Uncharacterized protein | / | 0.450 | |
| 3eem | 53V | Uncharacterized protein | / | 0.450 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.450 | |
| 3hfb | ML4 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.450 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.450 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.450 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.450 | |
| 4c2x | NHW | Glycylpeptide N-tetradecanoyltransferase 2 | / | 0.450 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 4eix | NIM | Phospholipase A2 VRV-PL-VIIIa | / | 0.450 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.450 | |
| 4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.450 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.450 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.450 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.449 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.449 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2ejz | SAH | Diphthine synthase | / | 0.449 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.449 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.449 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.449 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.449 | |
| 2z1x | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.449 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.449 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 3ge7 | AFQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3r73 | X87 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.449 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.449 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.449 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.449 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.449 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.449 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 5d12 | G97 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.448 | |
| 1c7o | PPG | Hemolysin | / | 0.448 | |
| 1cm8 | ANP | Mitogen-activated protein kinase 12 | / | 0.448 | |
| 1g28 | FMN | PHY3 | / | 0.448 | |
| 1jla | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1mj3 | HXC | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.448 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.448 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.448 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.448 | |
| 2w93 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.448 | |
| 2xvv | 9DN | Serum albumin | / | 0.448 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
| 3dok | GWJ | Pol protein | / | 0.448 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.448 | |
| 3jw3 | TOP | Dihydrofolate reductase | / | 0.448 | |
| 3owl | 19E | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.448 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.448 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.448 | |
| 4iae | 1DX | Alr2278 protein | / | 0.448 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.448 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.447 | |
| 1fml | RTL | Retinol dehydratase | / | 0.447 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.447 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.447 | |
| 1ppj | ANY | Cytochrome b | / | 0.447 | |
| 1qsr | ACO | HAT A1 | / | 0.447 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.447 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.447 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.447 | |
| 2buf | ADP | Acetylglutamate kinase | / | 0.447 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.447 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.447 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.447 | |
| 3b5i | SAH | Indole-3-acetate O-methyltransferase 1 | / | 0.447 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.447 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.447 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.447 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.447 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.447 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.447 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4f0f | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.447 | |
| 4f1m | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.447 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.447 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.447 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.447 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.447 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.447 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.447 | |
| 5dp2 | NAP | CurF | / | 0.447 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.447 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.447 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.447 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.446 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.446 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.446 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.446 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.446 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3gb4 | D3M | DdmC | / | 0.446 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.446 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.446 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.446 | |
| 3qp0 | NI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3rpo | 24Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.446 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.446 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4c2z | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.446 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.446 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.446 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.446 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.446 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.446 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.446 | |
| 5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 5dpv | SKE | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 5es7 | FON | Linear gramicidin synthase subunit A | / | 0.446 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.446 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.445 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.445 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.445 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.445 | |
| 1i3m | UD1 | UDP-glucose 4-epimerase | / | 0.445 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1kvo | OAP | Phospholipase A2, membrane associated | / | 0.445 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.445 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.445 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.445 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.445 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.445 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.445 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.445 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.445 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.445 | |
| 2ynf | WHU | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.445 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.445 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.445 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3r35 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.445 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.445 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.445 | |
| 3sqq | 99Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.445 | |
| 3uqd | ADP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.445 | |
| 3zly | YSO | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.445 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.445 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.445 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.445 | |
| 4hxo | 1A6 | Bromodomain-containing protein 4 | / | 0.445 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.445 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.445 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.445 | |
| 4o0s | ADN | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.445 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.445 | |
| 4uxq | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.445 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.445 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.445 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.444 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.444 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.444 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.444 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 3dmj | GWE | Pol protein | / | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3ls8 | AJZ | Phosphatidylinositol 3-kinase catalytic subunit type 3 | 2.7.1.137 | 0.444 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.444 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.444 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.444 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.444 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.444 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4bwx | AGS | PAB-dependent poly(A)-specific ribonuclease subunit pan3 | / | 0.444 | |
| 4egn | TWO | Cytochrome P450 | / | 0.444 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.444 | |
| 4hxs | 1A3 | Bromodomain-containing protein 4 | / | 0.444 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.444 | |
| 4mmf | 29Q | Na(+):neurotransmitter symporter (Snf family) | / | 0.444 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.444 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.444 | |
| 5f0a | 1FB | cGMP-dependent protein kinase, putative | / | 0.444 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1dcy | I3N | Phospholipase A2, membrane associated | / | 0.443 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.443 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.443 | |
| 1urw | I1P | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.443 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 2r3w | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.443 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.443 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.443 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.443 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.443 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.443 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.443 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.443 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.443 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.443 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.443 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 3zs5 | SB2 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4at2 | ASD | Possible succinate dehydrogenase | / | 0.443 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.443 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.443 | |
| 4i0t | 1B6 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.443 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.443 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 4oth | DRN | Serine/threonine-protein kinase N1 | / | 0.443 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.443 | |
| 5cu6 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.443 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.442 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1e8w | QUE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.442 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.442 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2eau | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.442 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3bqr | 4RB | Death-associated protein kinase 3 | / | 0.442 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.442 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.442 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.442 | |
| 3r6x | X84 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.442 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.442 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.442 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4hvg | 19Q | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.442 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.442 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.442 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.442 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.442 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.442 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.441 | |
| 1err | RAL | Estrogen receptor | / | 0.441 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 1rm3 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.441 | |
| 1s9e | ADB | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.441 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.441 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 2ouz | C3D | Estrogen receptor | / | 0.441 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.441 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.441 | |
| 3eek | 53S | Uncharacterized protein | / | 0.441 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.441 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3lxp | IZA | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.441 | |
| 3mfu | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3p9t | TCL | Repressor | / | 0.441 | |
| 3ql8 | X01 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.441 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.441 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.441 | |
| 4bbh | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4eop | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4eos | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.441 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.441 | |
| 4z07 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.441 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.440 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.440 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.440 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.440 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 1yol | S03 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 2jav | 5Z5 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.440 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.440 | |
| 2y37 | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.440 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
| 3eel | 53T | Uncharacterized protein | / | 0.440 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3nhu | M42 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3qqg | X06 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3qx2 | X63 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.440 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.440 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4c2y | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.440 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4f63 | 0S7 | Fibroblast growth factor receptor 1 | / | 0.440 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 4kwh | NAP | Reductase homolog | / | 0.440 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.440 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.440 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.440 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.440 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.440 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.440 |