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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4bwaN0BPyrrolysine--tRNA ligase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4bwaN0BPyrrolysine--tRNA ligase/1.000
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.517
3oafOAGDihydrofolate reductase1.5.1.30.510
3pe2E1BCasein kinase II subunit alpha2.7.11.10.506
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.503
5jtbZMAAdenosine receptor A2a/0.502
5k2aZMAAdenosine receptor A2a/0.497
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.495
5k2cZMAAdenosine receptor A2a/0.495
4kak06UDihydrofolate reductase1.5.1.30.493
3gieACPSensor histidine kinase DesK2.7.13.30.492
4c02TAKActivin receptor type-12.7.11.300.491
4dymIYZActivin receptor type-12.7.11.300.491
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.490
3vt7VDXVitamin D3 receptor/0.490
2itpAEEEpidermal growth factor receptor2.7.10.10.488
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.488
4kd79DRDihydrofolate reductase1.5.1.30.487
1rx8FOLDihydrofolate reductase1.5.1.30.486
2w3aTOPDihydrofolate reductase1.5.1.30.485
4eiyZMAAdenosine receptor A2a/0.485
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.484
4hqvQEIQueuine tRNA-ribosyltransferase2.4.2.290.483
5e8wSTUTGF-beta receptor type-12.7.11.300.483
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
2pulACPMethylthioribose kinase2.7.1.1000.480
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.480
5uviZMAAdenosine receptor A2a/0.478
5iua6DXAdenosine receptor A2a/0.478
2ewaSB2Mitogen-activated protein kinase 14/0.477
3h4vNAPPteridine reductase 11.5.1.330.477
3zze6XPHepatocyte growth factor receptor2.7.10.10.477
5d7pAR6NAD-dependent protein deacetylase sirtuin-23.5.10.477
3srsM23Dihydrofolate reductase1.5.1.30.476
3vt8YI3Vitamin D3 receptor/0.476
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
2nniMTKCytochrome P450 2C8/0.475
2pupADPMethylthioribose kinase2.7.1.1000.475
2zb45OPProstaglandin reductase 21.3.1.480.475
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.475
3w0tHPULactoylglutathione lyase4.4.1.50.475
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.474
2ykcYKCHeat shock protein HSP 90-alpha/0.474
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.474
3hz5Z64Heat shock protein HSP 90-alpha/0.474
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.474
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.474
3uzcT4EAdenosine receptor A2a/0.474
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.473
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.473
3ivcFG4Pantothenate synthetase6.3.2.10.473
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.473
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.473
1dr4HBIDihydrofolate reductase1.5.1.30.472
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.472
3anmNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.472
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
4gg70J8Hepatocyte growth factor receptor2.7.10.10.472
4j6cSTRCytochrome P450 monooxygenase/0.472
4xe606UDihydrofolate reductase1.5.1.30.472
5k2dZMAAdenosine receptor A2a/0.472
1k6tXN1Gag-Pol polyprotein3.4.23.160.471
2ociTYCValacyclovir hydrolase3.10.471
2w9hTOPDihydrofolate reductase1.5.1.30.471
3nwq2NCGag-Pol polyprotein3.4.23.160.471
3slkNDPPolyketide synthase extender module 2/0.471
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.471
4gg50J3Hepatocyte growth factor receptor2.7.10.10.471
4j4vSVRNucleocapsid protein/0.471
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
5fwgGPRGlutathione S-transferase Mu 12.5.1.180.471
1v0oINRCell division control protein 2 homolog2.7.11.220.470
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.470
2qqfA1RNAD-dependent protein deacetylase HST23.5.10.470
3fywXCFDihydrofolate reductase1.5.1.30.470
3nxtD2EDihydrofolate reductase1.5.1.30.470
3w0gW07Vitamin D3 receptor/0.470
4mgiCMPRap guanine nucleotide exchange factor 4/0.470
1dr2TAPDihydrofolate reductase1.5.1.30.469
2h96893Mitogen-activated protein kinase 82.7.11.240.469
2tscCB3Thymidylate synthase/0.469
3dleGFAGag-Pol polyprotein2.7.7.490.469
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.469
4h3zSAHtRNA (guanine-N(1)-)-methyltransferase/0.469
4hgt15GCasein kinase I isoform delta2.7.11.10.469
4kfj1R0Dihydrofolate reductase1.5.1.30.469
5d7qAR6NAD-dependent protein deacetylase sirtuin-23.5.10.469
1ke6LS2Cyclin-dependent kinase 22.7.11.220.468
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.468
3i8aN22Dihydrofolate reductase1.5.1.30.468
3sruQ26Dihydrofolate reductase1.5.1.30.468
4kbn25UDihydrofolate reductase1.5.1.30.468
5dr6SKEAurora kinase A2.7.11.10.468
1rx5DDFDihydrofolate reductase1.5.1.30.467
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.467
2hw2RFPRifampin ADP-ribosyl transferase/0.467
2oaxSNLMineralocorticoid receptor/0.467
2q7gCCLPyrrolysine--tRNA ligase/0.467
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.467
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
3lfcZ86Mitogen-activated protein kinase 14/0.467
3pqbVGPPutative oxidoreductase/0.467
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.467
3srwQ27Dihydrofolate reductase1.5.1.30.467
3up3XCAaceDAF-12/0.467
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.467
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.467
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.467
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.466
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.466
2qg2A91Heat shock protein HSP 90-alpha/0.466
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.466
3b9lAZZSerum albumin/0.466
3s1dZIRCytokinin dehydrogenase 11.5.99.120.466
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.466
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.466
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.466
1nzdUPGDNA beta-glucosyltransferase/0.465
2uxuNARHTH-type transcriptional regulator TtgR/0.465
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.465
3new3NEMitogen-activated protein kinase 14/0.465
3emlZMAAdenosine receptor A2a/0.465
1ai9NDPDihydrofolate reductase1.5.1.30.464
1di8DTQCyclin-dependent kinase 22.7.11.220.464
1j39UPGDNA beta-glucosyltransferase/0.464
1qzfFOLBifunctional dihydrofolate reductase-thymidylate synthase/0.464
2xngA0HAurora kinase A2.7.11.10.464
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
3qm4PN0Cytochrome P450 2D6/0.464
3w5rLOAVitamin D3 receptor/0.464
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.464
4gstGTDGlutathione S-transferase Mu 12.5.1.180.464
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.463
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.463
1kqwRTLCellular retinol-binding protein type II/0.463
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.463
1s3wTQTDihydrofolate reductase1.5.1.30.463
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.463
3hv3R49Mitogen-activated protein kinase 14/0.463
3nga3NGCasein kinase II subunit alpha2.7.11.10.463
3nwxKVSGag-Pol polyprotein3.4.23.160.463
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.463
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.463
4hni16WCasein kinase I isoform epsilon2.7.11.10.463
4lsl1YQGag-Pol polyprotein2.7.7.490.463
1m78NDPDihydrofolate reductase1.5.1.30.462
1nhz486Glucocorticoid receptor/0.462
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.462
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.462
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
2puiADPMethylthioribose kinase2.7.1.1000.462
2w9gTOPDihydrofolate reductase1.5.1.30.462
2x7hPFNProstaglandin reductase 310.462
3fy8XCFDihydrofolate reductase1.5.1.30.462
3jynNDPQuinone oxidoreductase/0.462
3l8sBFFMitogen-activated protein kinase 14/0.462
3rmf20ZCyclin-dependent kinase 22.7.11.220.462
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.462
4bfwZVWPantothenate kinase2.7.1.330.462
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.462
4k9oTPPBenzoylformate decarboxylase4.1.1.70.462
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
1klkPMDDihydrofolate reductase1.5.1.30.461
1lb9DNQGlutamate receptor 2/0.461
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.461
2bxmIMNSerum albumin/0.461
2gjnFMNNitronate monooxygenase1.13.12.160.461
3nr4PYVAbscisic acid receptor PYL2/0.461
4dpwAGSMevalonate diphosphate decarboxylase/0.461
4iah1DXAlr2278 protein/0.461
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.461
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
1f28UMPThymidylate synthase2.1.1.450.460
1ne4RP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.460
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
3c3dFO12-phospho-L-lactate transferase/0.460
3d0bSNXHeat shock protein HSP 90-alpha/0.460
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.460
3pe6ZYHMonoglyceride lipase/0.460
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.460
3vrwYS5Vitamin D3 receptor/0.460
3znsNU7Histone deacetylase 73.5.1.980.460
4elb34RDihydrofolate reductase/0.460
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.460
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.460
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
2ejvNADL-threonine 3-dehydrogenase/0.459
2itnANPEpidermal growth factor receptor2.7.10.10.459
2ittAEEEpidermal growth factor receptor2.7.10.10.459
2iw84SPCyclin-dependent kinase 22.7.11.220.459
2jedLG8Protein kinase C theta type2.7.11.130.459
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.459
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
2zdt46CMitogen-activated protein kinase 102.7.11.240.459
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.459
3biz61EWee1-like protein kinase2.7.10.20.459
3eljGS7Mitogen-activated protein kinase 82.7.11.240.459
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.459
3own3OWRenin3.4.23.150.459
3sai9DRDihydrofolate reductase/0.459
4c68NHWGlycylpeptide N-tetradecanoyltransferase/0.459
4elg52JDihydrofolate reductase/0.459
4fgh0U6Dihydrofolate reductase1.5.1.30.459
4g47TZFMycocyclosin synthase1.14.21.90.459
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.459
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.459
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.459
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1ouk084Mitogen-activated protein kinase 14/0.458
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.458
2a1nCAMCamphor 5-monooxygenase1.14.15.10.458
2bxqIMNSerum albumin/0.458
2j0k4STFocal adhesion kinase 12.7.10.20.458
2pujHPZ2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.458
2qd5CHDFerrochelatase, mitochondrial4.99.1.10.458
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.458
3ddpRC8Cyclin-dependent kinase 22.7.11.220.458
3gggNADPrephenate dehydrogenase/0.458
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.458
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
4h9506UDihydrofolate reductase1.5.1.30.458
4h9814QUncharacterized protein/0.458
4j7uYTZSepiapterin reductase1.1.1.1530.458
4nqmY1ZBromodomain-containing protein 4/0.458
4rupH97Vitamin D3 receptor A/0.458
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.458
1bwsNDPGDP-L-fucose synthase/0.457
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.457
1ia4TQ6Dihydrofolate reductase1.5.1.30.457
1p8dCO1Oxysterols receptor LXR-beta/0.457
1qxlFR8Adenosine deaminase3.5.4.40.457
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.457
1u0wSTLChalcone synthase 22.3.1.740.457
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.457
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.457
2mm3CHOGastrotropin/0.457
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.457
3lpbNVBTyrosine-protein kinase JAK2/0.457
3p8iFMNPentaerythritol tetranitrate reductase/0.457
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.457
1zhzERGOxysterol-binding protein homolog 4/0.456
2hk9NAPShikimate dehydrogenase (NADP(+))/0.456
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
2r64740Cyclin-dependent kinase 22.7.11.220.456
2vcmM11Isopenicillin N synthase1.21.3.10.456
2yac937Serine/threonine-protein kinase PLK12.7.11.210.456
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.456
3o8tBMUMitogen-activated protein kinase 14/0.456
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.456
4afeGGYSerine/threonine-protein kinase Nek22.7.11.10.456
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.456
4ea13RXDehydrosqualene synthase/0.456
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.456
4n57ADPAPH(2'')-Id/0.456
4p68MTXDihydrofolate reductase/0.456
1kkq471Peroxisome proliferator-activated receptor alpha/0.455
1kmsLIHDihydrofolate reductase1.5.1.30.455
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1yhoTRRDihydrofolate reductase1.5.1.30.455
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.455
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.455
2j0vGDPRac-like GTP-binding protein ARAC7/0.455
2z7gEH9Adenosine deaminase3.5.4.40.455
3b7dCNIGlutamate receptor 2/0.455
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.455
3fl8RARDihydrofolate reductase/0.455
3fy9XCFDihydrofolate reductase1.5.1.30.455
3iok1P6Tyrosine-protein kinase JAK2/0.455
3jpuTY4Transcriptional activator protein LasR/0.455
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3mdvCL6Cholesterol 24-hydroxylase/0.455
3zewSTUEphrin type-B receptor 42.7.10.10.455
4dc0NDPPutative ketoacyl reductase1.3.10.455
4fnyI3KALK tyrosine kinase receptor2.7.10.10.455
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.455
4g95OAGDihydrofolate reductase1.5.1.30.455
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4jq7KJQEpidermal growth factor receptor2.7.10.10.455
1i58ACPChemotaxis protein CheA2.7.13.30.454
1nvtNAPShikimate dehydrogenase (NADP(+))/0.454
1rx7FOLDihydrofolate reductase1.5.1.30.454
2jkqVG8Focal adhesion kinase 12.7.10.20.454
2ojg19AMitogen-activated protein kinase 12.7.11.240.454
2rhrEMOPutative ketoacyl reductase1.3.10.454
2xvw9NRSerum albumin/0.454
2z2w770Wee1-like protein kinase2.7.10.20.454
2zaxCAMCamphor 5-monooxygenase1.14.15.10.454
3c1xCKKHepatocyte growth factor receptor2.7.10.10.454
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.454
3jw5TOPDihydrofolate reductase/0.454
3kf7L9GMitogen-activated protein kinase 14/0.454
3m08RARDihydrofolate reductase1.5.1.30.454
3pd4A3GThreonine--tRNA ligase6.1.1.30.454
3q9bB3NAcetylpolyamine amidohydrolase/0.454
3qly55VUncharacterized protein/0.454
3vt9YI4Vitamin D3 receptor/0.454
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.454
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.454
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.454
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.454
1ia1NDPDihydrofolate reductase1.5.1.30.453
1lf2R37Plasmepsin-23.4.23.390.453
1oguST8Cyclin-dependent kinase 22.7.11.220.453
1vyrFMNPentaerythritol tetranitrate reductase/0.453
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2ev9NAPShikimate dehydrogenase (NADP(+))/0.453
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.453
2xk730ESerine/threonine-protein kinase Nek22.7.11.10.453
2yeiXQIHeat shock protein HSP 90-alpha/0.453
2znpK55Peroxisome proliferator-activated receptor delta/0.453
3at4CCKCasein kinase II subunit alpha2.7.11.10.453
3c3xNAPEugenol synthase 11.1.1.3180.453
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.453
3k47D09Dihydrofolate reductase1.5.1.30.453
3r0tFU9Casein kinase II subunit alpha2.7.11.10.453
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.453
3w5tLHPVitamin D3 receptor/0.453
4c2uANPDNA helicase/0.453
4ele31IDihydrofolate reductase/0.453
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.453
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4nc3ERM5-hydroxytryptamine receptor 2B/0.453
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.453
4tx9AMZPhosphoribosyl isomerase A/0.453
5dr9SKEAurora kinase A2.7.11.10.453
1fw0KAIGlutamate receptor 2/0.452
1jutLYDThymidylate synthase/0.452
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.452
1uy6PU3Heat shock protein HSP 90-alpha/0.452
1zhwHC2Oxysterol-binding protein homolog 4/0.452
1zrzBI1Protein kinase C iota type2.7.11.130.452
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.452
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.452
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.452
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.452
2w6mOA1Biotin carboxylase6.3.4.140.452
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3el4ROCGag-Pol polyprotein3.4.23.160.452
3gcq1BUMitogen-activated protein kinase 14/0.452
3nxoD2BDihydrofolate reductase1.5.1.30.452
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3s2pPMUCyclin-dependent kinase 22.7.11.220.452
4eh70OOMitogen-activated protein kinase 14/0.452
4iebANPCalmodulin-domain protein kinase 1/0.452
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.452
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.452
4ucnMYAGlycylpeptide N-tetradecanoyltransferase/0.452
5epvACPBlue-light-activated histidine kinase2.7.13.30.452
1bucFADAcyl-CoA dehydrogenase, short-chain specific1.3.8.10.451
1cdeGARPhosphoribosylglycinamide formyltransferase/0.451
1dr3HBIDihydrofolate reductase1.5.1.30.451
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
1lhvNOGSex hormone-binding globulin/0.451
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.451
1tl7ONMAdenylate cyclase type 2/0.451
1tl7ONMAdenylate cyclase type 5/0.451
1uyfPU1Heat shock protein HSP 90-alpha/0.451
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.451
2cchATPCyclin-dependent kinase 22.7.11.220.451
2itwITQEpidermal growth factor receptor2.7.10.10.451
2izrBRKCasein kinase I isoform gamma-32.7.11.10.451
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.451
2yboSAHMethyltransferase/0.451
3bfa9ODOdorant binding protein ASP1/0.451
3c6uM22Gag-Pol polyprotein2.7.7.490.451
3hucG97Mitogen-activated protein kinase 14/0.451
3iktNADRedox-sensing transcriptional repressor Rex/0.451
3jwcEKBDihydrofolate reductase/0.451
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.451
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.451
3zuxTCHTransporter/0.451
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4g1d0VKVitamin D3 receptor A/0.451
4h0xNADIota toxin component Ia/0.451
4h3g10QBeta-secretase 13.4.23.460.451
4h4qFADBiphenyl dioxygenase ferredoxin reductase subunit/0.451
4iteTEYVitamin D3 receptor/0.451
4j6dTESCytochrome P450 monooxygenase/0.451
4k28NADShikimate dehydrogenase family protein/0.451
4kjjFOLDihydrofolate reductase1.5.1.30.451
4l2yXXKPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.451
4lxhC1EAlpha/beta hydrolase fold/0.451
4ocvANPAminoglycoside phosphotransferase/0.451
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.451
5cshATPCasein kinase II subunit alpha2.7.11.10.451
5cvcPLPSerine racemase/0.451
5dr2ATPAurora kinase A2.7.11.10.451
5iu86DZAdenosine receptor A2a/0.451
3reyXACAdenosine receptor A2a/0.451
1h1r6CPCyclin-dependent kinase 22.7.11.220.450
1jioDEB6-deoxyerythronolide B hydroxylase/0.450
1ke9LS5Cyclin-dependent kinase 22.7.11.220.450
1mq0BRDCytidine deaminase3.5.4.50.450
2acwUPGGlycosyltransferase/0.450
2hb7O1CVitamin D3 receptor/0.450
2itvANPEpidermal growth factor receptor2.7.10.10.450
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
2wotZZGTGF-beta receptor type-12.7.11.300.450
2wsaMYAGlycylpeptide N-tetradecanoyltransferase/0.450
3d73NBBPheromone-binding protein ASP1/0.450
3eej53RUncharacterized protein/0.450
3eem53VUncharacterized protein/0.450
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.450
3hfbML4Tryptophan 5-hydroxylase 11.14.16.40.450
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.450
3r336MEDihydrofolate reductase1.5.1.30.450
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.450
3tdaPN0Cytochrome P450 2D6/0.450
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.450
4b1rITCTetracycline repressor protein class D/0.450
4c2xNHWGlycylpeptide N-tetradecanoyltransferase 2/0.450
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
4eixNIMPhospholipase A2 VRV-PL-VIIIa/0.450
4g1z0VPVitamin D3 receptor A/0.450
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.450
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.450
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.450
4riyADPEpidermal growth factor receptor2.7.10.10.450
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.450
4xldBRLPeroxisome proliferator-activated receptor gamma/0.450
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.449
1bsvNDPGDP-L-fucose synthase/0.449
1fm4DXCMajor pollen allergen Bet v 1-L/0.449
1opbRETRetinol-binding protein 2/0.449
1pd9CO4Dihydrofolate reductase1.5.1.30.449
1upw444Oxysterols receptor LXR-beta/0.449
1xl2189Gag-Pol polyprotein3.4.23.160.449
2ejzSAHDiphthine synthase/0.449
2fzjDH3Dihydrofolate reductase1.5.1.30.449
2oliIOPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.449
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.449
2q59240Peroxisome proliferator-activated receptor gamma/0.449
2q9fC3SCholesterol 24-hydroxylase/0.449
2wkyIBCGlutamate receptor ionotropic, kainate 1/0.449
2z1xPRFQueuine tRNA-ribosyltransferase2.4.2.290.449
2zb8IMNProstaglandin reductase 21.3.1.480.449
3a4pDFQHepatocyte growth factor receptor2.7.10.10.449
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.449
3d74NBBPheromone-binding protein ASP1/0.449
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.449
3hllI45Mitogen-activated protein kinase 14/0.449
3o0iP54Heat shock protein HSP 90-alpha/0.449
3r73X87Cyclin-dependent kinase 22.7.11.220.449
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.449
3vjoANPEpidermal growth factor receptor2.7.10.10.449
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.449
4cd2FOLDihydrofolate reductase1.5.1.30.449
4cdmFO1Deoxyribodipyrimidine photolyase/0.449
4ddrMMVDihydrofolate reductase1.5.1.30.449
4ea2RWZDehydrosqualene synthase/0.449
4eoi1ROCyclin-dependent kinase 22.7.11.220.449
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.449
4kbk1QGCasein kinase I isoform delta2.7.11.10.449
4lrrCF9Thymidylate synthase/0.449
4rh10TTSpore photoproduct lyase/0.449
5cccDDFDihydrofolate reductase1.5.1.30.449
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
5k2bZMAAdenosine receptor A2a/0.449
1al7HSTPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.448
1c7oPPGHemolysin/0.448
1cm8ANPMitogen-activated protein kinase 12/0.448
1g28FMNPHY3/0.448
1jlaTNKGag-Pol polyprotein2.7.7.490.448
1mj3HXCEnoyl-CoA hydratase, mitochondrial4.2.1.170.448
1umlFR4Adenosine deaminase3.5.4.40.448
1w6hTITPlasmepsin-23.4.23.390.448
1x2hLPALipoate-protein ligase A6.3.1.200.448
1xzqFONtRNA modification GTPase MnmE3.6.50.448
2bakAQZMitogen-activated protein kinase 14/0.448
2in6839Wee1-like protein kinase2.7.10.20.448
2w93TPPPyruvate decarboxylase isozyme 1/0.448
2xvv9DNSerum albumin/0.448
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.448
3dokGWJPol protein/0.448
3frfXCFDihydrofolate reductase1.5.1.30.448
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.448
3jw3TOPDihydrofolate reductase/0.448
3owl19ECasein kinase II subunit alpha2.7.11.10.448
3qlrQLRDihydrofolate reductase1.5.1.30.448
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
3vt3VDXVitamin D3 receptor/0.448
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.448
4a9yAQZMitogen-activated protein kinase 14/0.448
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.448
4em9TCEPeroxisome proliferator-activated receptor gamma/0.448
4fxy0W2Neurolysin, mitochondrial3.4.24.160.448
4iae1DXAlr2278 protein/0.448
4j7xSASSepiapterin reductase1.1.1.1530.448
4l4cCAMCamphor 5-monooxygenase1.14.15.10.448
1f4gTP4Thymidylate synthase/0.447
1fmlRTLRetinol dehydratase/0.447
1h1s4SPCyclin-dependent kinase 22.7.11.220.447
1icqOPD12-oxophytodienoate reductase 11.3.1.420.447
1ie8KH1Vitamin D3 receptor/0.447
1m2rMNYCasein kinase II subunit alpha2.7.11.10.447
1n71COAAac(6')-Ii protein/0.447
1ppjANYCytochrome b/0.447
1qsrACOHAT A1/0.447
1uy7PU4Heat shock protein HSP 90-alpha/0.447
1x8lOXRRetinol dehydratase/0.447
1xjdSTUProtein kinase C theta type2.7.11.130.447
1ykdCMPAdenylate cyclase/0.447
2bufADPAcetylglutamate kinase/0.447
2izsBRQCasein kinase I isoform gamma-32.7.11.10.447
2qblCAMCamphor 5-monooxygenase1.14.15.10.447
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.447
2zcePYLPyrrolysine--tRNA ligase/0.447
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.447
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.447
3eigMTXDihydrofolate reductase1.5.1.30.447
3ezrEZRCyclin-dependent kinase 22.7.11.220.447
3frdDHFDihydrofolate reductase1.5.1.30.447
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.447
3ictADPCoenzyme A disulfide reductase/0.447
3lqfNADGalactitol dehydrogenase/0.447
3q2mCKISpectinomycin phosphotransferase/0.447
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
3w0hW12Vitamin D3 receptor/0.447
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4f0fACPProbable serine/threonine-protein kinase roco42.7.11.10.447
4f1mACPProbable serine/threonine-protein kinase roco42.7.11.10.447
4fgg0U5Dihydrofolate reductase1.5.1.30.447
4i9i1DYTankyrase-12.4.2.300.447
4jq4IMNAldo-keto reductase family 1 member C2/0.447
4nb6444Nuclear receptor ROR-gamma/0.447
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.447
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.447
5auwQUEDeath-associated protein kinase 12.7.11.10.447
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.447
5dp2NAPCurF/0.447
5eccNAPDehydrofolate reductase type I/0.447
4uhrNGIAdenosine receptor A2a/0.447
3uzaT4GAdenosine receptor A2a/0.447
1bozPRDDihydrofolate reductase1.5.1.30.446
1dnaCB3Thymidylate synthase/0.446
1e9hINRCyclin-dependent kinase 22.7.11.220.446
1pkdUCNCyclin-dependent kinase 22.7.11.220.446
1q5dEPBEpothilone C/D epoxidase1.140.446
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.446
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.446
2p5uNADUDP-glucose 4-epimerase/0.446
2qbnCAMCamphor 5-monooxygenase1.14.15.10.446
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.446
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.446
3fyvXCFDihydrofolate reductase1.5.1.30.446
3gb4D3MDdmC/0.446
3ictFADCoenzyme A disulfide reductase/0.446
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3lpjZ75Beta-secretase 13.4.23.460.446
3lxiCAMCytochrome P450/0.446
3mtfA3FActivin receptor type-12.7.11.300.446
3oibFDAPutative acyl-CoA dehydrogenase/0.446
3qp0NI8Gag-Pol polyprotein3.4.23.160.446
3rpo24ZCyclin-dependent kinase 22.7.11.220.446
3s7a684Dihydrofolate reductase1.5.1.30.446
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
3sh25DRDihydrofolate reductase1.5.1.30.446
3sm2478Putative gag-pro-pol polyprotein/0.446
3srrQ20Dihydrofolate reductase1.5.1.30.446
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.446
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4c2zMYAGlycylpeptide N-tetradecanoyltransferase 1/0.446
4ez50RSCyclin-dependent kinase 62.7.11.220.446
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.446
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.446
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.446
4qa2SHHHistone deacetylase 83.5.1.980.446
4xbfFADLysine-specific histone demethylase 1A10.446
5auvAGIDeath-associated protein kinase 12.7.11.10.446
5av2KMPDeath-associated protein kinase 12.7.11.10.446
5dpvSKEAurora kinase A2.7.11.10.446
5es7FONLinear gramicidin synthase subunit A/0.446
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.446
5kf1ACOPredicted acetyltransferase/0.446
1cjwCOTSerotonin N-acetyltransferase/0.445
1cqp803Integrin alpha-L/0.445
1dliUDXUDP-glucose 6-dehydrogenase/0.445
1f4fTP3Thymidylate synthase/0.445
1i3mUD1UDP-glucose 4-epimerase/0.445
1k6pXN3Gag-Pol polyprotein3.4.23.160.445
1kvoOAPPhospholipase A2, membrane associated/0.445
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.445
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.445
1uydPU8Heat shock protein HSP 90-alpha/0.445
1vjy460TGF-beta receptor type-12.7.11.300.445
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
2eb3ANPEpidermal growth factor receptor2.7.10.10.445
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.445
2gpjFADSiderophore-interacting protein/0.445
2hamC33Vitamin D3 receptor/0.445
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.445
2olcADPMethylthioribose kinase2.7.1.1000.445
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.445
2pwlACPFibroblast growth factor receptor 2/0.445
2uxpCLMHTH-type transcriptional regulator TtgR/0.445
2ydoADNAdenosine receptor A2a/0.445
2ynfWHUGag-Pol polyprotein2.7.7.490.445
2zlcVDXVitamin D3 receptor/0.445
3a783EVVitamin D3 receptor/0.445
3c36KAIGlutamate receptor ionotropic, kainate 1/0.445
3ctj320Hepatocyte growth factor receptor2.7.10.10.445
3ddw055Glycogen phosphorylase, liver form2.4.1.10.445
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
3gxlQIGTGF-beta receptor type-12.7.11.300.445
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
3kvxFMYMitogen-activated protein kinase 102.7.11.240.445
3lanKBTGag-Pol polyprotein2.7.7.490.445
3r354CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.445
3r3f4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.445
3slz3TLPutative gag-pro-pol polyprotein/0.445
3sqq99ZCyclin-dependent kinase 22.7.11.220.445
3t3q9PLCytochrome P450 2A61.14.130.445
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.445
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.445
4fob0USALK tyrosine kinase receptor2.7.10.10.445
4h4xFADBiphenyl dioxygenase ferredoxin reductase subunit/0.445
4hvi19STyrosine-protein kinase JAK32.7.10.20.445
4hxo1A6Bromodomain-containing protein 4/0.445
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.445
4j6bPLOCytochrome P450 monooxygenase/0.445
4klrCHDFerrochelatase, mitochondrial4.99.1.10.445
4m9aFDAAcyl-CoA dehydrogenase/0.445
4o0sADNAurora kinase A2.7.11.10.445
4o0wADNAurora kinase A2.7.11.10.445
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.445
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.445
4uxq0LIFibroblast growth factor receptor 42.7.10.10.445
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.445
5fwnNAPPutative dehydrogenase/0.445
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.444
1ia3TQ5Dihydrofolate reductase1.5.1.30.444
1m17AQ4Epidermal growth factor receptor2.7.10.10.444
1oiyN41Cyclin-dependent kinase 22.7.11.220.444
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.444
1wvxBD4Death-associated protein kinase 12.7.11.10.444
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.444
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.444
2i40BLZCyclin-dependent kinase 22.7.11.220.444
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.444
2ovhAS0Progesterone receptor/0.444
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.444
2po7CHDFerrochelatase, mitochondrial4.99.1.10.444
2qk8MTXDihydrofolate reductase/0.444
2zbaZBATrichothecene 3-O-acetyltransferase/0.444
3dmjGWEPol protein/0.444
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.444
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.444
3nj0PYVAbscisic acid receptor PYL2/0.444
3ns2PYVAbscisic acid receptor PYL2/0.444
3oom507Activin receptor type-12.7.11.300.444
3q43D66M1 family aminopeptidase3.4.110.444
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.444
3sa16DRDihydrofolate reductase/0.444
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.444
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.444
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.444
4egnTWOCytochrome P450/0.444
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.444
4hxs1A3Bromodomain-containing protein 4/0.444
4jajXU1Aurora kinase A2.7.11.10.444
4jqeANPCasein kinase II subunit alpha2.7.11.10.444
4kwi1TJReductase homolog/0.444
4mmf29QNa(+):neurotransmitter symporter (Snf family)/0.444
4nx6FOLDihydrofolate reductase1.5.1.30.444
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.444
4xwzFADFructosyl amine:oxygen oxidoreductase/0.444
5e8ySTUTGF-beta receptor type-22.7.11.300.444
5f0a1FBcGMP-dependent protein kinase, putative/0.444
1ay0TPPTransketolase 12.2.1.10.443
1dcyI3NPhospholipase A2, membrane associated/0.443
1i5cADPChemotaxis protein CheA2.7.13.30.443
1jtuLYBThymidylate synthase/0.443
1urwI1PCyclin-dependent kinase 22.7.11.220.443
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2hasC3OVitamin D3 receptor/0.443
2p1v5TNRetinoic acid receptor RXR-alpha/0.443
2r3wG3GGag-Pol polyprotein3.4.23.160.443
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.443
2rqfJH3Hemolymph juvenile hormone binding protein/0.443
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.443
2vwu7X1Ephrin type-B receptor 42.7.10.10.443
2vwz7X6Ephrin type-B receptor 42.7.10.10.443
2xh9J01Uncharacterized protein/0.443
2ykjYKJHeat shock protein HSP 90-alpha/0.443
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.443
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.443
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.443
3bfb9ODPheromone-binding protein ASP1/0.443
3cgfJNFMitogen-activated protein kinase 102.7.11.240.443
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.443
3falREARetinoic acid receptor RXR-alpha/0.443
3h1vTK1Glucokinase2.7.1.20.443
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.443
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3lakKR1Gag-Pol polyprotein2.7.7.490.443
3nxxNDPDihydrofolate reductase1.5.1.30.443
3tubFPUTyrosine-protein kinase SYK2.7.10.20.443
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.443
3zs5SB2Mitogen-activated protein kinase 14/0.443
4at2ASDPossible succinate dehydrogenase/0.443
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.443
4bcmT7ZCyclin-dependent kinase 22.7.11.220.443
4dgo0JWCasein kinase II subunit alpha2.7.11.10.443
4e37NDPCatalase1.11.1.60.443
4eepFMNPhototropin-22.7.11.10.443
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.443
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.443
4i231C9Epidermal growth factor receptor2.7.10.10.443
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.443
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.443
4othDRNSerine/threonine-protein kinase N1/0.443
4u0mGTPCyclic GMP-AMP synthase/0.443
5cu6ATPCasein kinase II subunit alpha2.7.11.10.443
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.443
1crbRTLRetinol-binding protein 1/0.442
1db1VDXVitamin D3 receptor/0.442
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1gky5GPGuanylate kinase2.7.4.80.442
1py5PY1TGF-beta receptor type-12.7.11.300.442
1th6OINBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.442
2b55D31Cyclin-dependent kinase 22.7.11.220.442
2eauCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.442
2gjlFMNNitronate monooxygenase1.13.12.160.442
2hm9TRRDihydrofolate reductase1.5.1.30.442
2p1u4TNRetinoic acid receptor RXR-alpha/0.442
2x6dX6DAurora kinase A2.7.11.10.442
2ym1FADPhenylacetone monooxygenase1.14.13.920.442
2zjwREFCasein kinase II subunit alpha2.7.11.10.442
3at3ATKCasein kinase II subunit alpha2.7.11.10.442
3bqr4RBDeath-associated protein kinase 3/0.442
3cgdCOACoenzyme A disulfide reductase/0.442
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.442
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.442
3fln3FNMitogen-activated protein kinase 14/0.442
3jskAHZThiamine thiazole synthase/0.442
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.442
3lamKRPGag-Pol polyprotein2.7.7.490.442
3q3cNADNAD-dependent L-serine dehydrogenase/0.442
3qqkX02Cyclin-dependent kinase 22.7.11.220.442
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.442
3r6xX84Cyclin-dependent kinase 22.7.11.220.442
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.442
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.442
4b722FBBeta-secretase 13.4.23.460.442
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.442
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.442
4eftEFTHeat shock protein HSP 90-alpha/0.442
4fki09KCyclin-dependent kinase 22.7.11.220.442
4hvg19QTyrosine-protein kinase JAK32.7.10.20.442
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.442
4jbtASDCytochrome P450 monooxygenase/0.442
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.442
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.442
4o71CPBBromodomain-containing protein 4/0.442
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.442
4y93746Tyrosine-protein kinase/0.442
1dkfBMSRetinoic acid receptor alpha/0.441
1errRALEstrogen receptor/0.441
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1nzfUPGDNA beta-glucosyltransferase/0.441
1ouy094Mitogen-activated protein kinase 14/0.441
1rm3NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.441
1s9eADBGag-Pol polyprotein2.7.7.490.441
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.441
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.441
2fpcSCGStrictosidine synthase4.3.3.20.441
2hk51BMTyrosine-protein kinase HCK2.7.10.20.441
2ouzC3DEstrogen receptor/0.441
2punACPMethylthioribose kinase2.7.1.1000.441
2pvnP63Casein kinase II subunit alpha2.7.11.10.441
2wouZZFTGF-beta receptor type-12.7.11.300.441
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.441
3dd125DGlycogen phosphorylase, liver form2.4.1.10.441
3eek53SUncharacterized protein/0.441
3fwjCAMCamphor 5-monooxygenase1.14.15.10.441
3g70A5TRenin3.4.23.150.441
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.441
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.441
3p9tTCLRepressor/0.441
3ql8X01Cyclin-dependent kinase 22.7.11.220.441
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
3r9hZ67Cyclin-dependent kinase 22.7.11.220.441
3sgy06WDihydrofolate reductase1.5.1.30.441
3t3r9PLCytochrome P450 2A61.14.130.441
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.441
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.441
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.441
4a9e3PFBromodomain-containing protein 2/0.441
4bbhNHWGlycylpeptide N-tetradecanoyltransferase/0.441
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4eop1ROCyclin-dependent kinase 22.7.11.220.441
4eos1ROCyclin-dependent kinase 22.7.11.220.441
4equG6ISerine/threonine-protein kinase 102.7.11.10.441
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.441
4z07PCGcGMP-dependent protein kinase 12.7.11.120.441
5cp4CAMCamphor 5-monooxygenase1.14.15.10.441
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1aoeGW3Dihydrofolate reductase1.5.1.30.440
1csnATPCasein kinase I homolog 12.7.11.10.440
1fmjRTLRetinol dehydratase/0.440
1gs4ZK5Androgen receptor/0.440
1ia2TQ4Dihydrofolate reductase1.5.1.30.440
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1m2qMNXCasein kinase II subunit alpha2.7.11.10.440
1phgMYTCamphor 5-monooxygenase1.14.15.10.440
1rw8580TGF-beta receptor type-12.7.11.300.440
1s7gNADNAD-dependent protein deacylase 2/0.440
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.440
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.440
2hcdBIVVitamin D3 receptor A/0.440
2hl1A3SThreonine--tRNA ligase6.1.1.30.440
2j0m4STFocal adhesion kinase 12.7.10.20.440
2jav5Z5Serine/threonine-protein kinase Nek22.7.11.10.440
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.440
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.440
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.440
2y37H4BNitric oxide synthase, inducible1.14.13.390.440
2y9qANPMitogen-activated protein kinase 12.7.11.240.440
2yn8STUEphrin type-B receptor 42.7.10.10.440
3cth319Hepatocyte growth factor receptor2.7.10.10.440
3eel53TUncharacterized protein/0.440
3fhxPXLPyridoxal kinase2.7.1.350.440
3fznD7KBenzoylformate decarboxylase4.1.1.70.440
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.440
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.440
3l0lHC3Nuclear receptor ROR-gamma/0.440
3mdmFJZCholesterol 24-hydroxylase/0.440
3nhuM42Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
3q9xEMOCasein kinase II subunit alpha2.7.11.10.440
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3qdd94MHeat shock protein HSP 90-alpha/0.440
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3qqgX06Cyclin-dependent kinase 22.7.11.220.440
3qx2X63Cyclin-dependent kinase 22.7.11.220.440
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.440
3tucFPWTyrosine-protein kinase SYK2.7.10.20.440
3u4uLNHCasein kinase II subunit alpha2.7.11.10.440
3uyt0CKCasein kinase I isoform delta2.7.11.10.440
3v1mHPK2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.440
3zpuM8BGag-Pol polyprotein3.4.23.160.440
4c2yMYAGlycylpeptide N-tetradecanoyltransferase 1/0.440
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4f630S7Fibroblast growth factor receptor 1/0.440
4hge15VTyrosine-protein kinase JAK2/0.440
4ia3BIVVitamin D3 receptor A/0.440
4k9yK9YFocal adhesion kinase 12.7.10.20.440
4kb81QNCasein kinase I isoform delta2.7.11.10.440
4kwhNAPReductase homolog/0.440
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.440
4nbwNADShort-chain dehydrogenase/reductase SDR/0.440
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.440
4qysPLRTryptophan synthase beta chain 24.2.1.200.440
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.440
4wboANWRhodopsin kinase/0.440
4zqcF6FTryptophan synthase alpha chain/0.440
2rh1CAUBeta-2 adrenergic receptor/0.440