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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4but31FTankyrase-22.4.2.30

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4but31FTankyrase-22.4.2.301.000
4buuF38Tankyrase-22.4.2.300.892
4l0s1UZTankyrase-22.4.2.300.883
4bu908CTankyrase-22.4.2.300.823
4buiW2ETankyrase-22.4.2.300.809
4hlk431Tankyrase-22.4.2.300.741
4bufF36Tankyrase-22.4.2.300.639
4l10A63Tankyrase-22.4.2.300.617
3kr8XAVTankyrase-22.4.2.300.594
4bud29FTankyrase-22.4.2.300.590
4j22AJ7Tankyrase-22.4.2.300.579
4kzuA73Tankyrase-22.4.2.300.577
4l31F08Tankyrase-22.4.2.300.567
4hknLU2Tankyrase-22.4.2.300.557
4hkkAGITankyrase-22.4.2.300.525
5aku29FTankyrase-22.4.2.300.500
4l341VGTankyrase-22.4.2.300.494
4l2f1V3Tankyrase-22.4.2.300.484
4hlg20BTankyrase-22.4.2.300.482
4l0t1V0Tankyrase-22.4.2.300.481
4l0v1V1Tankyrase-22.4.2.300.463
4kzl20DTankyrase-22.4.2.300.456