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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4bufF36Tankyrase-22.4.2.30

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4bufF36Tankyrase-22.4.2.301.000
4buiW2ETankyrase-22.4.2.300.691
4hlk431Tankyrase-22.4.2.300.683
4but31FTankyrase-22.4.2.300.644
4buuF38Tankyrase-22.4.2.300.633
3kr8XAVTankyrase-22.4.2.300.621
4l0s1UZTankyrase-22.4.2.300.617
4l31F08Tankyrase-22.4.2.300.615
4bu908CTankyrase-22.4.2.300.613
4bud29FTankyrase-22.4.2.300.612
4l10A63Tankyrase-22.4.2.300.605
4hknLU2Tankyrase-22.4.2.300.601
4kzuA73Tankyrase-22.4.2.300.600
4j22AJ7Tankyrase-22.4.2.300.597
4hkkAGITankyrase-22.4.2.300.564
4l0t1V0Tankyrase-22.4.2.300.511
5aku29FTankyrase-22.4.2.300.511
4l341VGTankyrase-22.4.2.300.492
4l33F70Tankyrase-22.4.2.300.490
4hlg20BTankyrase-22.4.2.300.471
4l0v1V1Tankyrase-22.4.2.300.466
4l0i1UWTankyrase-22.4.2.300.465
4l2f1V3Tankyrase-22.4.2.300.458
4iueAJ4Tankyrase-22.4.2.300.456
4hlf15ZTankyrase-22.4.2.300.454
4kzl20DTankyrase-22.4.2.300.453
4bueJQFTankyrase-22.4.2.300.447
4l321VFTankyrase-22.4.2.300.443