Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4bueJQFTankyrase-22.4.2.30

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4bueJQFTankyrase-22.4.2.301.000
4buxF35Tankyrase-22.4.2.300.786
4l0t1V0Tankyrase-22.4.2.300.784
4hlh20DTankyrase-22.4.2.300.743
4l2g1V4Tankyrase-22.4.2.300.742
4bus32FTankyrase-22.4.2.300.706
4buwF33Tankyrase-22.4.2.300.702
4l341VGTankyrase-22.4.2.300.686
4bs4A64Tankyrase-22.4.2.300.673
4hlf15ZTankyrase-22.4.2.300.649
4l0i1UWTankyrase-22.4.2.300.648
4iueAJ4Tankyrase-22.4.2.300.647
4l321VFTankyrase-22.4.2.300.639
4l31F08Tankyrase-22.4.2.300.628
3kr8XAVTankyrase-22.4.2.300.626
4bu908CTankyrase-22.4.2.300.626
4l0s1UZTankyrase-22.4.2.300.621
5aku29FTankyrase-22.4.2.300.620
4bufF36Tankyrase-22.4.2.300.619
4buuF38Tankyrase-22.4.2.300.618
4l0v1V1Tankyrase-22.4.2.300.611
4j22AJ7Tankyrase-22.4.2.300.610
4l33F70Tankyrase-22.4.2.300.609
4kzl20DTankyrase-22.4.2.300.606
4l10A63Tankyrase-22.4.2.300.606
4kzuA73Tankyrase-22.4.2.300.602
4l2f1V3Tankyrase-22.4.2.300.602
4buiW2ETankyrase-22.4.2.300.601
4but31FTankyrase-22.4.2.300.597
4hlm16STankyrase-22.4.2.300.592
4hkkAGITankyrase-22.4.2.300.590
3p0pNNFTankyrase-22.4.2.300.588
4avwG18Tankyrase-22.4.2.300.588
4l2k1V8Tankyrase-22.4.2.300.586
4bj9UHBTankyrase-22.4.2.300.582
4hl515WTankyrase-22.4.2.300.582
4hknLU2Tankyrase-22.4.2.300.576
4j21AJ6Tankyrase-22.4.2.300.574
4pnrG18Tankyrase-22.4.2.300.560
4tkg09LTankyrase-22.4.2.300.559
4hmhF94Tankyrase-22.4.2.300.537
4hkiFLNTankyrase-22.4.2.300.518
4bjbP34Tankyrase-22.4.2.300.510
4msk2C8Tankyrase-12.4.2.300.508
4k4eK4ETankyrase-12.4.2.300.493
3tqcADPPantothenate kinase/0.472
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.470
4buv16ITankyrase-22.4.2.300.470
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.468
4hlk431Tankyrase-22.4.2.300.460
4avuLDRTankyrase-22.4.2.300.455
4hyf1AKTankyrase-22.4.2.300.455
4tjy3GNTankyrase-22.4.2.300.455
3rsv3RSBeta-secretase 13.4.23.460.451
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.449
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.449
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.449
4i9i1DYTankyrase-12.4.2.300.449
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.448
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442