sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4bfy	ZVY	Pantothenate kinase	2.7.1.33

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4bfy	ZVY	Pantothenate kinase	2.7.1.33	1.000
4bfz	ZVZ	Pantothenate kinase	2.7.1.33	0.499
3af0	GDP	Pantothenate kinase	2.7.1.33	0.486
2get	COK	Pantothenate kinase	2.7.1.33	0.484
4bfw	ZVW	Pantothenate kinase	2.7.1.33	0.472
2gev	COK	Pantothenate kinase	2.7.1.33	0.469
4bfu	ZVU	Pantothenate kinase	2.7.1.33	0.464
2zsd	COA	Pantothenate kinase	2.7.1.33	0.460
3af1	GDP	Pantothenate kinase	2.7.1.33	0.460
4bfx	ZVX	Pantothenate kinase	2.7.1.33	0.458
2zsb	ADP	Pantothenate kinase	2.7.1.33	0.457
2zs9	ADP	Pantothenate kinase	2.7.1.33	0.454
3af4	GCP	Pantothenate kinase	2.7.1.33	0.454
3af2	ACP	Pantothenate kinase	2.7.1.33	0.453
2zse	ACP	Pantothenate kinase	2.7.1.33	0.451
2ges	COK	Pantothenate kinase	2.7.1.33	0.448