sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4bcr	WY1	Peroxisome proliferator-activated receptor alpha

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4bcr	WY1	Peroxisome proliferator-activated receptor alpha	/	1.000
3sp6	IL2	Peroxisome proliferator-activated receptor alpha	/	0.598
1k7l	544	Peroxisome proliferator-activated receptor alpha	/	0.560
1y0s	331	Peroxisome proliferator-activated receptor delta	/	0.557
1i7g	AZ2	Peroxisome proliferator-activated receptor alpha	/	0.528
2znn	S44	Peroxisome proliferator-activated receptor alpha	/	0.506
2znq	401	Peroxisome proliferator-activated receptor delta	/	0.490
2znp	K55	Peroxisome proliferator-activated receptor delta	/	0.480
2i4z	DRH	Peroxisome proliferator-activated receptor gamma	/	0.465
3sp9	IL2	Peroxisome proliferator-activated receptor delta	/	0.458
2i4p	DRH	Peroxisome proliferator-activated receptor gamma	/	0.456
3vn2	TLS	Peroxisome proliferator-activated receptor gamma	/	0.452
3vso	EK1	Peroxisome proliferator-activated receptor gamma	/	0.452
4e4q	RRH	Peroxisome proliferator-activated receptor gamma	/	0.450
4xuh	SFI	Peroxisome proliferator-activated receptor gamma	/	0.450
2om9	AJA	Peroxisome proliferator-activated receptor gamma	/	0.445
1fm9	570	Peroxisome proliferator-activated receptor gamma	/	0.444
2i4j	DRJ	Peroxisome proliferator-activated receptor gamma	/	0.442
3vjh	J35	Peroxisome proliferator-activated receptor gamma	/	0.442