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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4bcdTDVProlyl endopeptidase3.4.21.26

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4bcdTDVProlyl endopeptidase3.4.21.261.000
1e8mP0HProlyl endopeptidase3.4.21.260.826
1uopGLY_PHE_GLU_PROProlyl endopeptidase3.4.21.260.706
3eq9X97Prolyl endopeptidase3.4.21.260.504
1uooGLY_PHE_ARG_PROProlyl endopeptidase3.4.21.260.450
1yb5NAPQuinone oxidoreductase1.6.5.50.440