sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4b68	FAD	L-ornithine N(5)-monooxygenase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4b68	FAD	L-ornithine N(5)-monooxygenase	/	1.000
4b63	FAD	L-ornithine N(5)-monooxygenase	/	0.618
4b65	FAD	L-ornithine N(5)-monooxygenase	/	0.606
4b66	FAD	L-ornithine N(5)-monooxygenase	/	0.600
5cku	FAD	L-ornithine N(5)-monooxygenase	/	0.582
4b64	FAD	L-ornithine N(5)-monooxygenase	/	0.561
3s5w	FAD	L-ornithine N(5)-monooxygenase	/	0.495
4b67	FAD	L-ornithine N(5)-monooxygenase	/	0.492
4tlx	FDA	KtzI	/	0.476
4nzh	FAD	L-ornithine N(5)-monooxygenase	/	0.464
4tm1	FDA	KtzI	/	0.459
4tm4	FDA	KtzI	/	0.458
4tlz	FAD	KtzI	/	0.450