sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4b67	FAD	L-ornithine N(5)-monooxygenase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4b67	FAD	L-ornithine N(5)-monooxygenase	/	1.000
4b68	FAD	L-ornithine N(5)-monooxygenase	/	0.639
4b66	FAD	L-ornithine N(5)-monooxygenase	/	0.629
4b63	FAD	L-ornithine N(5)-monooxygenase	/	0.604
4b64	FAD	L-ornithine N(5)-monooxygenase	/	0.585
5cku	FAD	L-ornithine N(5)-monooxygenase	/	0.571
3s5w	FAD	L-ornithine N(5)-monooxygenase	/	0.532
4b65	FAD	L-ornithine N(5)-monooxygenase	/	0.520
4tlz	FAD	KtzI	/	0.503
4tm4	FDA	KtzI	/	0.498
4tm1	FDA	KtzI	/	0.496
4tlx	FDA	KtzI	/	0.491
4nzh	FAD	L-ornithine N(5)-monooxygenase	/	0.473
4tm3	FAD	KtzI	/	0.441