sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4az0 | S61 | Lysosomal protective protein | 3.4.16.5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4az0 | S61 | Lysosomal protective protein | 3.4.16.5 | 1.000 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.633 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.458 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.456 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.450 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.450 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.448 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 5f8f | SFG | Possible transcriptional regulatory protein | / | 0.443 | |
| 1dv2 | ATP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.440 |