sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ax9 | N5N | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 1.000 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.680 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.674 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.657 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.649 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.647 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.624 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.602 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.594 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.592 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.592 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.591 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.580 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.573 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.569 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.568 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.567 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.566 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.562 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.560 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.556 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.552 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.544 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.543 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.542 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.540 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.538 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.537 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.534 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.534 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.526 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.524 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.523 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.522 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.522 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.521 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.521 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.518 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.516 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.516 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.514 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.509 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.509 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.508 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.506 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.504 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.503 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.499 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.499 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.497 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.494 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.490 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.488 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.485 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.484 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.483 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.483 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.483 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.479 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.478 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.477 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.477 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.475 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.472 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.468 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.468 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.465 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.465 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.463 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.456 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.455 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.450 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.445 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.443 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.443 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.441 |