sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ap0 | ADP | Kinesin-like protein KIF11 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ap0 | ADP | Kinesin-like protein KIF11 | / | 1.000 | |
| 2gm1 | ADP | Kinesin-like protein KIF11 | / | 0.513 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.459 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.458 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.455 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.454 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.450 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1pt5 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.448 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.446 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.443 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.443 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.442 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.442 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.441 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.440 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 |