sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4ac0	MIY	Tetracycline repressor protein class B from transposon Tn10

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4ac0	MIY	Tetracycline repressor protein class B from transposon Tn10	/	1.000
2o7o	DXT	Tetracycline repressor protein class D	/	0.498
1ork	ATC	Tetracycline repressor protein class D	/	0.487
4b3a	TAC	Tetracycline repressor protein class D	/	0.473
5fkm	TDC	Tetracycline repressor protein class D	/	0.472
4aux	XTC	Tetracycline repressor protein class D	/	0.469
5fkl	TDC	Tetracycline repressor protein class D	/	0.455
2tct	CTC	Tetracycline repressor protein class D	/	0.449
2xpw	OTC	Tetracycline repressor protein class D	/	0.443