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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4aacAAVMitogen-activated protein kinase 14

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4aacAAVMitogen-activated protein kinase 14/1.000
4aa4QC0Mitogen-activated protein kinase 14/0.768
3fklFKLMitogen-activated protein kinase 14/0.511
3flwFLWMitogen-activated protein kinase 14/0.499
4kiq1RAMitogen-activated protein kinase 14/0.492
4kip1R9Mitogen-activated protein kinase 14/0.478
3mvl38PMitogen-activated protein kinase 14/0.474
3fskRO6Mitogen-activated protein kinase 14/0.468
3nww3NWMitogen-activated protein kinase 14/0.460
3hl7I47Mitogen-activated protein kinase 14/0.459
3iphG11Mitogen-activated protein kinase 14/0.459
3u8w09JMitogen-activated protein kinase 14/0.448
3hllI45Mitogen-activated protein kinase 14/0.443