sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4a39 | GEM | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4a39 | GEM | Uncharacterized protein | / | 1.000 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.477 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.473 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.459 | |
| 3jq3 | ADP | Lombricine kinase | / | 0.455 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3q5p | TAC | Multidrug-efflux transporter 1 regulator | / | 0.450 | |
| 3isi | B88 | Putative dipeptidase | / | 0.449 | |
| 4rkd | KET | Aminotransferase | / | 0.449 | |
| 1aj2 | 2PH | Dihydropteroate synthase | / | 0.448 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.447 | |
| 4kxj | P34 | Nucleoprotein | / | 0.446 | |
| 1kru | IPT | Galactoside O-acetyltransferase | 2.3.1.18 | 0.445 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.444 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.444 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.441 | |
| 5ero | 210 | Fusicoccadiene synthase | 2.5.1.29 | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.440 |