Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3zsgT75Mitogen-activated protein kinase 14

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3zsgT75Mitogen-activated protein kinase 14/1.000
3hucG97Mitogen-activated protein kinase 14/0.573
3zs5SB2Mitogen-activated protein kinase 14/0.555
3mpaSB2Mitogen-activated protein kinase 14/0.473
2ewaSB2Mitogen-activated protein kinase 14/0.468
4k5o1OTM1 family aminopeptidase3.4.110.465
2lbvEB4Extracellular fatty acid-binding protein/0.461
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.460
3gcpSB2Mitogen-activated protein kinase 14/0.458
1ouy094Mitogen-activated protein kinase 14/0.456
4jazSTLPeroxisome proliferator-activated receptor gamma/0.456
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.453
2gtk208Peroxisome proliferator-activated receptor gamma/0.451
2o0uC0MMitogen-activated protein kinase 102.7.11.240.451
3ttiKBIMitogen-activated protein kinase 102.7.11.240.451
4k5p1OSM1 family aminopeptidase3.4.110.447
4xldBRLPeroxisome proliferator-activated receptor gamma/0.447
3k5uPFQAurora kinase A2.7.11.10.446
3ttjJBIMitogen-activated protein kinase 102.7.11.240.443
2o2u738Mitogen-activated protein kinase 102.7.11.240.442
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.441
4xumIMNPeroxisome proliferator-activated receptor gamma/0.441
3h0aD30Peroxisome proliferator-activated receptor gamma/0.440
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.440