Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3znr | NU9 | Histone deacetylase 7 | 3.5.1.98 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
3znr | NU9 | Histone deacetylase 7 | 3.5.1.98 | 1.000 | |
3zns | NU7 | Histone deacetylase 7 | 3.5.1.98 | 0.611 | |
4cby | KEE | Histone deacetylase 4 | 3.5.1.98 | 0.598 | |
3c10 | TSN | Histone deacetylase 7 | 3.5.1.98 | 0.570 | |
2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.562 | |
4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.546 | |
4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.523 | |
1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.522 | |
3c0z | SHH | Histone deacetylase 7 | 3.5.1.98 | 0.521 | |
3uza | T4G | Adenosine receptor A2a | / | 0.514 | |
3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.511 | |
3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.510 | |
4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.509 | |
1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.506 | |
1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.506 | |
1fmj | RTL | Retinol dehydratase | / | 0.505 | |
3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.505 | |
4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.505 | |
3djf | BC3 | Purine nucleoside phosphorylase | / | 0.503 | |
4dm8 | REA | Retinoic acid receptor beta | / | 0.503 | |
1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.501 | |
3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.501 | |
5g53 | NEC | Adenosine receptor A2a | / | 0.500 | |
1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.498 | |
5kf9 | ACO | Predicted acetyltransferase | / | 0.498 | |
5k2a | ZMA | Adenosine receptor A2a | / | 0.496 | |
2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.495 | |
3up3 | XCA | aceDAF-12 | / | 0.495 | |
1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.494 | |
4imf | SI3 | N-acetylneuraminate lyase | / | 0.494 | |
2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.493 | |
5k2c | ZMA | Adenosine receptor A2a | / | 0.492 | |
3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.491 | |
2qhx | FE1 | Pteridine reductase 1 | 1.5.1.33 | 0.490 | |
5kf8 | ACO | Predicted acetyltransferase | / | 0.490 | |
3uzc | T4E | Adenosine receptor A2a | / | 0.489 | |
2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.488 | |
3p9t | TCL | Repressor | / | 0.488 | |
4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.488 | |
4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.488 | |
2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.487 | |
3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.486 | |
3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.486 | |
3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
4fhd | 0TT | Spore photoproduct lyase | / | 0.485 | |
3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.484 | |
3eml | ZMA | Adenosine receptor A2a | / | 0.484 | |
1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.483 | |
2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.483 | |
3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.483 | |
5kgp | ACO | Predicted acetyltransferase | / | 0.483 | |
1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.482 | |
3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.482 | |
4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.481 | |
4qii | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.481 | |
4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.481 | |
5iua | 6DX | Adenosine receptor A2a | / | 0.481 | |
1el4 | CTZ | Obelin | / | 0.480 | |
2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.480 | |
4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.480 | |
4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.480 | |
1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
1qv0 | CZH | Obelin | / | 0.479 | |
2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.479 | |
3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.479 | |
3jwc | EKB | Dihydrofolate reductase | / | 0.479 | |
3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.479 | |
2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.478 | |
2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.478 | |
3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.478 | |
2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.477 | |
2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.477 | |
2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.477 | |
2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.477 | |
3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.477 | |
3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.477 | |
5uvi | ZMA | Adenosine receptor A2a | / | 0.477 | |
1syn | F89 | Thymidylate synthase | / | 0.476 | |
2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.476 | |
3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.476 | |
3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
4eiy | ZMA | Adenosine receptor A2a | / | 0.476 | |
4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.476 | |
5jtb | ZMA | Adenosine receptor A2a | / | 0.476 | |
1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.474 | |
3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.474 | |
3x06 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.474 | |
4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.474 | |
4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.474 | |
1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.473 | |
2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.473 | |
2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.473 | |
3q7f | ED2 | Uncharacterized protein | / | 0.473 | |
3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.473 | |
4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.473 | |
5k2d | ZMA | Adenosine receptor A2a | / | 0.473 | |
1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.472 | |
2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.472 | |
2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.472 | |
4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.472 | |
3qak | UKA | Adenosine receptor A2a | / | 0.472 | |
1jf2 | CZH | Obelin | / | 0.471 | |
1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.471 | |
1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.471 | |
2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.471 | |
4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
4bwa | N0B | Pyrrolysine--tRNA ligase | / | 0.471 | |
5kgj | ACO | Predicted acetyltransferase | / | 0.471 | |
1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.470 | |
1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.470 | |
2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.470 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
1qv1 | CZH | Obelin | / | 0.469 | |
2xtb | KRM | Adenosine kinase, putative | / | 0.469 | |
3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.469 | |
4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.469 | |
4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.469 | |
4mrx | CZH | Obelin | / | 0.469 | |
1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
1fw0 | KAI | Glutamate receptor 2 | / | 0.468 | |
1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.468 | |
2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.468 | |
4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.468 | |
4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
3rey | XAC | Adenosine receptor A2a | / | 0.468 | |
1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.467 | |
1swt | BTN | Streptavidin | / | 0.467 | |
1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.467 | |
2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.467 | |
2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.467 | |
2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
2qqf | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.467 | |
2yat | EEU | Estrogen receptor | / | 0.467 | |
3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.467 | |
3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.467 | |
4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.467 | |
4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.467 | |
4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
4iah | 1DX | Alr2278 protein | / | 0.467 | |
4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
1lbb | KAI | Glutamate receptor 2 | / | 0.466 | |
1lhw | ESM | Sex hormone-binding globulin | / | 0.466 | |
2od7 | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.466 | |
2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.466 | |
1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.465 | |
1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.465 | |
1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.465 | |
2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.465 | |
2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.465 | |
3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.465 | |
3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.465 | |
4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.465 | |
1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.464 | |
1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.464 | |
2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.464 | |
3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.464 | |
4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.464 | |
4iae | 1DX | Alr2278 protein | / | 0.464 | |
4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
5kf2 | ACO | Predicted acetyltransferase | / | 0.464 | |
2ejz | SAH | Diphthine synthase | / | 0.463 | |
2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.463 | |
2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.463 | |
2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.463 | |
3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
4du6 | GTP | GTP cyclohydrolase 1 | / | 0.463 | |
4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.463 | |
5agy | GTB | Tau class glutathione S-transferase | / | 0.463 | |
3pwh | ZMA | Adenosine receptor A2a | / | 0.463 | |
1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.462 | |
1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.462 | |
2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
2x9v | TMQ | Pteridine reductase | / | 0.462 | |
3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.462 | |
3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.462 | |
4ax8 | SAM | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.462 | |
4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.462 | |
5k2b | ZMA | Adenosine receptor A2a | / | 0.462 | |
2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.461 | |
2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.461 | |
2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.461 | |
2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
3l6j | Z90 | Alr2278 protein | / | 0.461 | |
3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
4ap1 | NAP | Steroid monooxygenase | / | 0.461 | |
4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.461 | |
4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.461 | |
4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.461 | |
4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.461 | |
1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.460 | |
2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.460 | |
2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.460 | |
2w0h | NDP | Trypanothione reductase | / | 0.460 | |
2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.460 | |
2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.460 | |
3oji | PYV | Abscisic acid receptor PYL3 | / | 0.460 | |
3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
3tm5 | SFG | Uncharacterized protein | / | 0.460 | |
4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.460 | |
5kgh | ACO | Predicted acetyltransferase | / | 0.460 | |
1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.459 | |
2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.459 | |
2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.459 | |
2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.459 | |
3bld | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.459 | |
3bmq | AX5 | Pteridine reductase | / | 0.459 | |
3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.459 | |
3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.459 | |
3htj | ET | EbrA repressor | / | 0.459 | |
3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
4f31 | KAI | Glutamate receptor 3 | / | 0.459 | |
4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.459 | |
4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.459 | |
5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.459 | |
1jdz | FMB | Purine nucleoside phosphorylase | / | 0.458 | |
1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.458 | |
1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.458 | |
1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
2a4x | BLM | Mitomycin-binding protein | / | 0.458 | |
2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.458 | |
2jav | 5Z5 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.458 | |
2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.458 | |
3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.458 | |
3huc | G97 | Mitogen-activated protein kinase 14 | / | 0.458 | |
3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.458 | |
3lql | LDT | Aldose reductase | 1.1.1.21 | 0.458 | |
3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.458 | |
4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.458 | |
4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.458 | |
4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.458 | |
5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.458 | |
5iu8 | 6DZ | Adenosine receptor A2a | / | 0.458 | |
1q63 | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.457 | |
1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.457 | |
2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.457 | |
2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.457 | |
3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.457 | |
3dko | IHZ | Ephrin type-A receptor 7 | 2.7.10.1 | 0.457 | |
4fhf | 0TT | Spore photoproduct lyase | / | 0.457 | |
4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
4ixd | 1HV | Integrin alpha-L | / | 0.457 | |
5doz | NDP | JamJ | / | 0.457 | |
1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.456 | |
1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.456 | |
1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.456 | |
2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.456 | |
2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.456 | |
3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.456 | |
3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.456 | |
3nmv | PYV | Abscisic acid receptor PYL2 | / | 0.456 | |
3s41 | S41 | Glucokinase | 2.7.1.2 | 0.456 | |
3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.456 | |
4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.456 | |
4azw | SAM | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.456 | |
4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.456 | |
4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.456 | |
1iah | ADP | Transient receptor potential cation channel subfamily M member 7 | 2.7.11.1 | 0.455 | |
1qs2 | NAD | Vip2Ac | / | 0.455 | |
1s9d | AFB | Cytohesin-2 | / | 0.455 | |
1s9d | AFB | ADP-ribosylation factor 1 | / | 0.455 | |
1ych | FMN | Nitric oxide reductase | 1 | 0.455 | |
2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.455 | |
2jbl | SMA | Reaction center protein L chain | / | 0.455 | |
2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.455 | |
3fzt | 4JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.455 | |
3q2m | CKI | Spectinomycin phosphotransferase | / | 0.455 | |
4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
4agw | NG7 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.455 | |
4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.455 | |
5cfn | 2BA | Stimulator of interferon genes protein | / | 0.455 | |
1g7u | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.454 | |
1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.454 | |
1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.454 | |
1qsn | COA | HAT A1 | / | 0.454 | |
1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
1rxj | BNI | Streptavidin | / | 0.454 | |
1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.454 | |
1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.454 | |
2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.454 | |
2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.454 | |
3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.454 | |
1ftl | DNQ | Glutamate receptor 2 | / | 0.453 | |
1ve3 | SAM | Uncharacterized protein | / | 0.453 | |
2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.453 | |
2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.453 | |
3arv | SAU | Chitinase A | / | 0.453 | |
3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.453 | |
3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
3cqw | CQW | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.453 | |
3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.453 | |
3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
3ele | PLP | Aminotransferase | / | 0.453 | |
3lzz | GDP | Uncharacterized protein | / | 0.453 | |
3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.453 | |
3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.453 | |
4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.453 | |
4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.453 | |
4hfp | 15U | Prothrombin | 3.4.21.5 | 0.453 | |
4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
4zqc | F6F | Tryptophan synthase alpha chain | / | 0.453 | |
5c8d | 5AD | Probable transcriptional regulator | / | 0.453 | |
1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.452 | |
1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.452 | |
2b1z | 17M | Estrogen receptor | / | 0.452 | |
2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.452 | |
2fai | 459 | Estrogen receptor | / | 0.452 | |
2lbd | REA | Retinoic acid receptor gamma | / | 0.452 | |
2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.452 | |
2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
2p15 | EZT | Estrogen receptor | / | 0.452 | |
2ydo | ADN | Adenosine receptor A2a | / | 0.452 | |
3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
3njo | PYV | Abscisic acid receptor PYR1 | / | 0.452 | |
3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.452 | |
3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
3zsg | T75 | Mitogen-activated protein kinase 14 | / | 0.452 | |
4eix | NIM | Phospholipase A2 VRV-PL-VIIIa | / | 0.452 | |
4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.452 | |
4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.452 | |
4jqh | 1MF | Alr2278 protein | / | 0.452 | |
4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.452 | |
4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.452 | |
4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.452 | |
4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.452 | |
3rfm | CFF | Adenosine receptor A2a | / | 0.452 | |
1u08 | PLP | Methionine aminotransferase | / | 0.451 | |
2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.451 | |
2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.451 | |
3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.451 | |
3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.451 | |
3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.451 | |
3sl2 | ATP | Sensor histidine kinase WalK | / | 0.451 | |
4a2a | ATP | Cell division protein FtsA | / | 0.451 | |
4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.451 | |
4dm6 | TTB | Retinoic acid receptor beta | / | 0.451 | |
4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
4nbb | 9CA | Terminal oxygenase component of carbazole | / | 0.451 | |
4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.451 | |
1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
1ej3 | CZH | Aequorin-2 | / | 0.450 | |
1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.450 | |
2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.450 | |
2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
2h7j | H7J | Cathepsin S | 3.4.22.27 | 0.450 | |
2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.450 | |
2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.450 | |
3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.450 | |
3ogx | H1S | Peptidoglycan recognition protein 1 | / | 0.450 | |
3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
4bew | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
4dhy | S41 | Glucokinase | 2.7.1.2 | 0.450 | |
4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.450 | |
4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.450 | |
4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.450 | |
1dgf | NDP | Catalase | 1.11.1.6 | 0.449 | |
1dtn | APG | Mandelate racemase | / | 0.449 | |
1fcy | 564 | Retinoic acid receptor gamma | / | 0.449 | |
1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.449 | |
1nce | CB3 | Thymidylate synthase | / | 0.449 | |
2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.449 | |
2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.449 | |
2gpj | FAD | Siderophore-interacting protein | / | 0.449 | |
2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.449 | |
3nwl | NDP | Catalase | 1.11.1.6 | 0.449 | |
3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.449 | |
4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.449 | |
4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.449 | |
4gvs | F4M | Methenyltetrahydromethanopterin cyclohydrolase | 3.5.4.27 | 0.449 | |
4h0y | NAD | Iota toxin component Ia | / | 0.449 | |
4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.449 | |
4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
4lwa | Q13 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.449 | |
4o95 | 245 | Cytokinin dehydrogenase 4 | / | 0.449 | |
4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.449 | |
4qzu | RTL | Retinol-binding protein 2 | / | 0.449 | |
4uof | DAT | Nucleoside diphosphate kinase | / | 0.449 | |
4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.449 | |
5c1g | GDU | Histo-blood group ABO system transferase | / | 0.449 | |
5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.449 | |
4uhr | NGI | Adenosine receptor A2a | / | 0.449 | |
1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.448 | |
1c7o | PPG | Hemolysin | / | 0.448 | |
1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.448 | |
1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
1jf0 | CZH | Obelin | / | 0.448 | |
1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.448 | |
1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
2k1q | GLU_LEU_IBU_OBF_FE3 | Polyprotein | / | 0.448 | |
2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
3gb4 | D3M | DdmC | / | 0.448 | |
3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.448 | |
3imx | B84 | Glucokinase | 2.7.1.2 | 0.448 | |
3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.448 | |
3jpu | TY4 | Transcriptional activator protein LasR | / | 0.448 | |
3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.448 | |
3x2f | NAI | Adenosylhomocysteinase | / | 0.448 | |
4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
4fc0 | 0T2 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.448 | |
4gt8 | ADP | Sensor protein VraS | 2.7.13.3 | 0.448 | |
4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.448 | |
5d5b | CAU | Beta-2 adrenergic receptor | / | 0.448 | |
1cqp | 803 | Integrin alpha-L | / | 0.447 | |
1jcm | 137 | Tryptophan biosynthesis protein TrpCF | 4.1.1.48 | 0.447 | |
1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.447 | |
1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.447 | |
1zyd | ATP | eIF-2-alpha kinase GCN2 | / | 0.447 | |
2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.447 | |
2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.447 | |
2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.447 | |
2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.447 | |
2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.447 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.447 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.447 | |
3ge7 | AFQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.447 | |
3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
3rm8 | RM8 | Acidic mammalian chitinase | 3.2.1.14 | 0.447 | |
4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.447 | |
4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.447 | |
4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.447 | |
4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.447 | |
5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
5ecc | NAP | Dehydrofolate reductase type I | / | 0.447 | |
4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.447 | |
1afs | TES | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.446 | |
1mc1 | PCX | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.446 | |
1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.446 | |
1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.446 | |
1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
2cje | DUN | DUTPase | / | 0.446 | |
2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.446 | |
3gts | D3M | DdmC | / | 0.446 | |
3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.446 | |
3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.446 | |
3rbq | GLY_ALA_GLY_ALA_DAO | Protein unc-119 homolog A | / | 0.446 | |
3seq | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.446 | |
3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.446 | |
4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.446 | |
4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.446 | |
4eer | FMN | Phototropin-2 | 2.7.11.1 | 0.446 | |
4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.446 | |
4j6c | STR | Cytochrome P450 monooxygenase | / | 0.446 | |
4ku7 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.446 | |
4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.446 | |
4rh1 | 0TT | Spore photoproduct lyase | / | 0.446 | |
4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.446 | |
4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.446 | |
5epe | SAH | Uncharacterized protein | / | 0.446 | |
5iu4 | ZMA | Adenosine receptor A2a | / | 0.446 | |
5jqh | CAU | Beta-2 adrenergic receptor | / | 0.446 | |
1b9i | PXG | 3-amino-5-hydroxybenzoate synthase | 4.2.1.144 | 0.445 | |
1fd0 | 254 | Retinoic acid receptor gamma | / | 0.445 | |
1h9z | RWF | Serum albumin | / | 0.445 | |
1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.445 | |
1rgs | CMP | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.445 | |
1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.445 | |
1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.445 | |
2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.445 | |
2oth | NIM | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.445 | |
2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.445 | |
2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.445 | |
3l2k | PXC | EhpF | / | 0.445 | |
3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.445 | |
3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.445 | |
3vgn | FNN | Steroid Delta-isomerase | 5.3.3.1 | 0.445 | |
4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.445 | |
4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
4nqg | CZH | Mitrocomin | / | 0.445 | |
4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.445 | |
5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.445 | |
5bn3 | ADP | NEQ263 | / | 0.445 | |
1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
1giq | NAI | Iota toxin component Ia | / | 0.444 | |
1gnw | GTX | Glutathione S-transferase F2 | 2.5.1.18 | 0.444 | |
1kij | NOV | DNA gyrase subunit B | / | 0.444 | |
1mq0 | BRD | Cytidine deaminase | 3.5.4.5 | 0.444 | |
1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.444 | |
2bd0 | BIO | Sepiapterin reductase | / | 0.444 | |
2cle | F6F | Tryptophan synthase alpha chain | / | 0.444 | |
2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.444 | |
2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.444 | |
3gue | UPG | UTP-glucose-1-phosphate uridylyltransferase 2, putative | / | 0.444 | |
3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.444 | |
3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.444 | |
3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.444 | |
3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.444 | |
3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.444 | |
4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
4ea2 | RWZ | Dehydrosqualene synthase | / | 0.444 | |
4f1m | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.444 | |
4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.444 | |
4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.444 | |
4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
4zs4 | ATP | Myosin heavy chain kinase A | 2.7.11.7 | 0.444 | |
5dp2 | NAP | CurF | / | 0.444 | |
5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.444 | |
1hk5 | T44 | Serum albumin | / | 0.443 | |
1m8j | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.443 | |
1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
1qoq | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.443 | |
3bbf | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.443 | |
3gwf | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.443 | |
3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.443 | |
3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
3u8d | U8D | Phospholipase A2, membrane associated | / | 0.443 | |
3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.443 | |
4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.443 | |
4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
4fkx | CDP | Nucleoside diphosphate kinase | / | 0.443 | |
4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.443 | |
4zhi | ADP | Kinesin-like protein KIF11 | / | 0.443 | |
5dsg | 0HK | Muscarinic acetylcholine receptor M4 | / | 0.443 | |
1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
1jtq | LY3 | Thymidylate synthase | / | 0.442 | |
1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
1tez | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.442 | |
2c42 | TPP | Pyruvate synthase | / | 0.442 | |
2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.442 | |
2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.442 | |
3eah | 327 | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.442 | |
3mb6 | 01I | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.442 | |
3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.442 | |
3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.442 | |
4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
4bdr | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.442 | |
4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.442 | |
4dju | 0KK | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
4e37 | NDP | Catalase | 1.11.1.6 | 0.442 | |
4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
4gqk | ADP | Actin cross-linking toxin VgrG1 | / | 0.442 | |
4l2y | XXK | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.442 | |
4wcx | SAM | Biotin and thiamin synthesis associated | / | 0.442 | |
4y1b | NAP | AntE | / | 0.442 | |
4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.442 | |
5c1m | CLR | Mu-type opioid receptor | / | 0.442 | |
5je2 | SAH | Methyl transferase | / | 0.442 | |
1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
1d7o | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.441 | |
1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
1swg | BTN | Streptavidin | / | 0.441 | |
1upw | 444 | Oxysterols receptor LXR-beta | / | 0.441 | |
1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.441 | |
1w2c | ANP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.441 | |
1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.441 | |
2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.441 | |
2nv7 | 555 | Estrogen receptor beta | / | 0.441 | |
2vz0 | D64 | Pteridine reductase | / | 0.441 | |
2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.441 | |
2y67 | N21 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
3akl | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.441 | |
3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.441 | |
3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.441 | |
3gkj | HC3 | Niemann-Pick C1 protein | / | 0.441 | |
3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.441 | |
3pqb | VGP | Putative oxidoreductase | / | 0.441 | |
3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.441 | |
3wqu | ATP | Cell division protein FtsA | / | 0.441 | |
3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.441 | |
4f3g | KAI | Glutamate receptor 3 | / | 0.441 | |
4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
4gkt | 0O1 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.441 | |
4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.441 | |
1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.440 | |
1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
1djq | FMN | Trimethylamine dehydrogenase | 1.5.8.2 | 0.440 | |
1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.440 | |
1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.440 | |
1zdw | FLV | Prenyltransferase | / | 0.440 | |
2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.440 | |
2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.440 | |
2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 | |
2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.440 | |
2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.440 | |
2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
3cgy | RDC | Virulence sensor histidine kinase PhoQ | 2.7.13.3 | 0.440 | |
3l67 | FMN | Xenobiotic reductase | / | 0.440 | |
3qlx | QLR | Uncharacterized protein | / | 0.440 | |
3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.440 | |
3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.440 | |
3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.440 | |
4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.440 | |
4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
4cry | ACO | PanD regulatory factor | / | 0.440 | |
4hfn | CIY | 2-alkenal reductase (NADP(+)-dependent) | / | 0.440 | |
4j6d | TES | Cytochrome P450 monooxygenase | / | 0.440 | |
4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.440 | |
4lsj | LSJ | Glucocorticoid receptor | / | 0.440 | |
4pxm | EST | Estrogen receptor | / | 0.440 | |
4rxp | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
4y6g | F6F | Tryptophan synthase alpha chain | / | 0.440 | |
4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.440 |