sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3zgn | 10G | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3zgn | 10G | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 1.000 | |
| 4h4d | 10E | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.638 | |
| 3kem | IPE | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.595 | |
| 3zgl | 10E | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.517 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.498 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.498 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.497 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.497 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.497 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.497 | |
| 4l4x | NDP | AmphI | / | 0.497 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.494 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.494 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.494 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.493 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.493 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.491 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.491 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.489 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.489 | |
| 4eb3 | 0O3 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.489 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.488 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.488 | |
| 4hxy | NDP | Plm1 | / | 0.488 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.487 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.486 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.486 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.486 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.485 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.485 | |
| 3ke8 | EIP | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.483 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.482 | |
| 3utd | 0CJ | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.482 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.481 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.481 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.479 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.479 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.479 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.478 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.478 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.478 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.478 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.477 | |
| 1osv | CHC | Bile acid receptor | / | 0.477 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.477 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.477 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.477 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.477 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.476 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.476 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.475 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.475 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.475 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.475 | |
| 4h4c | 10D | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.475 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.474 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.474 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.474 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.473 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.473 | |
| 2p2j | PRX | Acetyl-coenzyme A synthetase | / | 0.473 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.473 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.473 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.473 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.472 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.472 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.471 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
| 3lm9 | ADP | Putative fructokinase | 2.7.1.4 | 0.471 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.471 | |
| 4kwh | NAP | Reductase homolog | / | 0.471 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.471 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.471 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.470 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.470 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.470 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.470 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.469 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.469 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.469 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.469 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.469 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.469 | |
| 1rqj | RIS | Farnesyl diphosphate synthase | 2.5.1.10 | 0.468 | |
| 1s1p | NAP | Aldo-keto reductase family 1 member C3 | / | 0.468 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.468 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.468 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.468 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.468 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.468 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.468 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.468 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.468 | |
| 1ori | SAH | Protein arginine N-methyltransferase 1 | / | 0.467 | |
| 1sny | NAP | LD36273p | / | 0.467 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.467 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.467 | |
| 2rew | REW | Peroxisome proliferator-activated receptor alpha | / | 0.467 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.467 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.467 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.466 | |
| 1zdw | FLV | Prenyltransferase | / | 0.466 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.466 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.466 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.466 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.466 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.466 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.466 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.465 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.465 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.465 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.465 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.464 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.464 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.464 | |
| 1rby | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.464 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.464 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.464 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.464 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.464 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.464 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.464 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.464 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.464 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.463 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.463 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.463 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.462 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.462 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.462 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.462 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.462 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.462 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 4wlu | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.462 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.461 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.461 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.461 | |
| 1njs | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.461 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.461 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.461 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.461 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.461 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.461 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.461 | |
| 4y1b | NAP | AntE | / | 0.461 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.461 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.460 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.460 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.460 | |
| 3dvl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.460 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.460 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.460 | |
| 3s3r | 0IW | Cathepsin B-like peptidase (C01 family) | / | 0.460 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.460 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.460 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.459 | |
| 2p2m | PRX | Acetyl-coenzyme A synthetase | / | 0.459 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.459 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 3qi2 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.459 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.459 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.458 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.458 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.458 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.458 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.458 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.458 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.458 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.458 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.458 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.458 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.458 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.458 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.458 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.457 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.457 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.457 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.457 | |
| 2jd0 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.457 | |
| 3eks | CY9 | Actin-5C | / | 0.457 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.457 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.457 | |
| 4dxh | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.457 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.457 | |
| 4pzd | NAD | 3-Hydroxyacyl-CoA dehydrogenase | / | 0.457 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.456 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.456 | |
| 1pzf | A3D | Lactate dehydrogenase | / | 0.456 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.456 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.456 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.456 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.456 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.456 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.456 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.456 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.455 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.455 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.455 | |
| 1m2h | APR | NAD-dependent protein deacylase 1 | / | 0.455 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.455 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.455 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.455 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.455 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.455 | |
| 4die | C5P | Cytidylate kinase | / | 0.455 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.455 | |
| 4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.455 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 4z9r | NAD | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.455 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.454 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.454 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 2p5c | SAH | Diphthine synthase | / | 0.454 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.454 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.454 | |
| 2wo9 | 068 | Macrophage metalloelastase | 3.4.24.65 | 0.454 | |
| 2xw1 | 9NV | Serum albumin | / | 0.454 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.454 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.454 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.454 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.454 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.454 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.454 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.453 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.453 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.453 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.453 | |
| 1ppj | ANY | Cytochrome b | / | 0.453 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.453 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.453 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.453 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.453 | |
| 4mlh | VO2 | Glucokinase | 2.7.1.2 | 0.453 | |
| 4o0m | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.453 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.453 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.453 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.452 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.452 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.452 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.452 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.452 | |
| 2pa3 | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.452 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.452 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.452 | |
| 3t94 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.452 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.452 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4m99 | ACO | UDP-N-acetylgalactosaminyltransferase | / | 0.452 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.452 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.452 | |
| 4yp5 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.452 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.452 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.451 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.451 | |
| 1mei | MOA | Inosine-5'-monophosphate dehydrogenase | / | 0.451 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.451 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.451 | |
| 1tys | DHF | Thymidylate synthase | / | 0.451 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.451 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.451 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.451 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.451 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4a7b | 3W5 | Collagenase 3 | 3.4.24 | 0.451 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.451 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 4jic | FMN | GTN Reductase | / | 0.451 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.451 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.451 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.451 | |
| 5fkn | TDC | Tetracycline repressor protein class D | / | 0.451 | |
| 5kl9 | COA | Acyl-CoA thioester hydrolase YbgC | 3.1.2 | 0.451 | |
| 1fnn | ADP | ORC1-type DNA replication protein | / | 0.450 | |
| 1ksz | PGS | Adenylosuccinate synthetase | / | 0.450 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.450 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.450 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.450 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.450 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.450 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.450 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.450 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.450 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.450 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.449 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.449 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.449 | |
| 1ztq | 033 | Collagenase 3 | 3.4.24 | 0.449 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.449 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.449 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.449 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.449 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.449 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.449 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.449 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.449 | |
| 3ete | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.449 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4bqu | CLR | Japanin | / | 0.449 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.449 | |
| 4h4e | 10G | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.449 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.449 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.449 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.448 | |
| 1llu | NAD | Alcohol dehydrogenase | / | 0.448 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.448 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.448 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 2hjr | APR | Malate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase | / | 0.448 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.448 | |
| 2jd1 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.448 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.448 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.448 | |
| 2oz0 | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.448 | |
| 2ozr | GG1 | Collagenase 3 | 3.4.24 | 0.448 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.448 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.448 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.448 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.448 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.448 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.448 | |
| 3e8c | G96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.448 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.448 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 4ajp | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.448 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.448 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.448 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.447 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.447 | |
| 2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.447 | |
| 2yig | 5EL | Collagenase 3 | 3.4.24 | 0.447 | |
| 3am5 | TCL | Enoyl-ACP reductase | / | 0.447 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.447 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.447 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.447 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.447 | |
| 3wbf | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.447 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.447 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.447 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.447 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.447 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4wxl | BB2 | Peptide deformylase | / | 0.447 | |
| 5dp2 | NAP | CurF | / | 0.447 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.446 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.446 | |
| 1r2j | FAD | FkbI | / | 0.446 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.446 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.446 | |
| 2uw0 | GVK | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.446 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.446 | |
| 3lpg | Z78 | Beta-glucuronidase | 3.2.1.31 | 0.446 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.446 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.446 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.446 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.446 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.446 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.446 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.446 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.446 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 | 0.446 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.446 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.446 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.446 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.445 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.445 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 1u3w | FXY | Alcohol dehydrogenase 1C | 1.1.1.1 | 0.445 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.445 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.445 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.445 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.445 | |
| 2wbb | RO3 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.445 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.445 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.445 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.445 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.445 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.445 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 3nwz | COA | BH2602 protein | / | 0.445 | |
| 3onw | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.445 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.445 | |
| 3sls | 77D | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.445 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.445 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.445 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.445 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.445 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.445 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.445 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.445 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.445 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.445 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.445 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.444 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.444 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.444 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.444 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.444 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.444 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.444 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.444 | |
| 2bhi | SFT | Cytotoxin 3 | / | 0.444 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.444 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.444 | |
| 2uw7 | GVP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.444 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.444 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.444 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.444 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.444 | |
| 4yfy | 1YJ | VioF | / | 0.444 | |
| 1caq | DPS | Stromelysin-1 | 3.4.24.17 | 0.443 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1iy8 | NAD | Levodione reductase | / | 0.443 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.443 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.443 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.443 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.443 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.443 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.443 | |
| 2ejz | SAH | Diphthine synthase | / | 0.443 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.443 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 2g37 | FAD | Proline dehydrogenase | / | 0.443 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.443 | |
| 2qrq | S13 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.443 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.443 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.443 | |
| 3dnd | LL2 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.443 | |
| 3v0t | ATR | Perakine reductase | 1.1.1.317 | 0.443 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.443 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.443 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.443 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.443 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.443 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.442 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.442 | |
| 1g6n | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.442 | |
| 1jje | BYS | Beta-lactamase | / | 0.442 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.442 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 1xur | PB5 | Collagenase 3 | 3.4.24 | 0.442 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2j62 | GSZ | O-GlcNAcase NagJ | / | 0.442 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.442 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.442 | |
| 2v8p | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.442 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3ecg | 065 | Gag-Pol polyprotein | 3.4.23.47 | 0.442 | |
| 3eku | CY9 | Actin-5C | / | 0.442 | |
| 3udk | 095 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.442 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3zux | TCH | Transporter | / | 0.442 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.442 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.442 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.442 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.442 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.442 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.442 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.442 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.441 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.441 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.441 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.441 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.441 | |
| 1rbq | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.441 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.441 | |
| 1uh5 | TCL | Enoyl-ACP reductase | / | 0.441 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 2bxm | IMN | Serum albumin | / | 0.441 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.441 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.441 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.441 | |
| 2p2b | PRX | Acetyl-coenzyme A synthetase | / | 0.441 | |
| 2p2q | PRX | Acetyl-coenzyme A synthetase | / | 0.441 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.441 | |
| 2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.441 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 3nfa | CBJ | Gag-Pol polyprotein | / | 0.441 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.441 | |
| 3v4e | COA | Putative acetyltransferase SACOL2570 | 2.3.1 | 0.441 | |
| 3vi2 | HMZ | Orotidine 5'-monophosphate decarboxylase | / | 0.441 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.441 | |
| 4al4 | W7E | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.441 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.441 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.441 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.441 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.440 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.440 | |
| 1ve9 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.440 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.440 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.440 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.440 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.440 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.440 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.440 | |
| 2wa2 | SAM | Genome polyprotein | / | 0.440 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.440 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.440 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 3awh | FMN | FMN-binding protein | / | 0.440 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.440 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.440 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.440 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.440 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.440 | |
| 4l3q | 926 | Glucokinase | 2.7.1.2 | 0.440 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.440 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.440 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.440 | |
| 4yp7 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.440 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.440 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.440 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.440 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.440 |