Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 1.000 | |
3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.759 | |
4aoi | 4K0 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.704 | |
4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.626 | |
2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.613 | |
4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.597 | |
4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.593 | |
3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.575 | |
4ap7 | F47 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.572 | |
3zbx | 6XE | Hepatocyte growth factor receptor | 2.7.10.1 | 0.550 | |
3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.547 | |
2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.536 | |
5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.535 | |
2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.520 | |
4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.518 | |
3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.514 | |
4iwd | 1JC | Hepatocyte growth factor receptor | 2.7.10.1 | 0.507 | |
2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.506 | |
4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.506 | |
2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.504 | |
4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.502 | |
4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.501 | |
3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.498 | |
3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.498 | |
4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.497 | |
2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.496 | |
4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.495 | |
4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.494 | |
3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.493 | |
1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.492 | |
4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.492 | |
2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.491 | |
3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.491 | |
3pl8 | FAD | Pyranose 2-oxidase | / | 0.491 | |
1kl2 | FON | Serine hydroxymethyltransferase | / | 0.490 | |
4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.490 | |
1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.489 | |
4de5 | 0JD | Pantothenate synthetase | 6.3.2.1 | 0.488 | |
3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.487 | |
3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.487 | |
4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.487 | |
2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.486 | |
2oyf | IAC | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.486 | |
4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.486 | |
1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.485 | |
1x8l | OXR | Retinol dehydratase | / | 0.485 | |
3kn5 | ANP | Ribosomal protein S6 kinase alpha-5 | 2.7.11.1 | 0.485 | |
4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.485 | |
2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.484 | |
3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.483 | |
1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.482 | |
1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.482 | |
3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.482 | |
2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
2ybo | SAH | Methyltransferase | / | 0.481 | |
3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
3frq | ERY | Erythromycin resistance repressor protein | / | 0.480 | |
4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.480 | |
2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.479 | |
3ibq | ATP | Pyridoxal kinase | / | 0.479 | |
4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.479 | |
4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.479 | |
2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.478 | |
3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.478 | |
4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.478 | |
1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.477 | |
3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.477 | |
4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.477 | |
4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.477 | |
4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.477 | |
4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.477 | |
5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.477 | |
3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.476 | |
3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.476 | |
3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.476 | |
1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
2fto | CB3 | Thymidylate synthase | / | 0.475 | |
3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.475 | |
3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.475 | |
2j5x | GSP | ADP-ribosylation factor 6 | / | 0.474 | |
2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.474 | |
3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.474 | |
3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.474 | |
4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
4n6z | 2HW | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.474 | |
1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.473 | |
3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.473 | |
4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.473 | |
5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
2xiy | XIY | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.472 | |
2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.471 | |
2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.471 | |
3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.471 | |
4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.471 | |
5eyp | LOC | Tubulin beta chain | / | 0.471 | |
1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.470 | |
1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.470 | |
3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.470 | |
3krw | BA1 | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.470 | |
3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.470 | |
3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.470 | |
3tnw | F18 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
4alh | A9P | Bromodomain-containing protein 2 | / | 0.470 | |
4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.470 | |
4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.470 | |
1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.469 | |
2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.469 | |
2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
2vmy | FFO | Serine hydroxymethyltransferase | / | 0.469 | |
2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.469 | |
2xvv | 9DN | Serum albumin | / | 0.469 | |
4ct1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.469 | |
4uyg | 73B | Bromodomain-containing protein 2 | / | 0.469 | |
1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.468 | |
2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.468 | |
3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.468 | |
3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.468 | |
3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.468 | |
3nnu | EDB | Mitogen-activated protein kinase 14 | / | 0.468 | |
3qai | XNN | Ketohexokinase | / | 0.468 | |
1cqp | 803 | Integrin alpha-L | / | 0.467 | |
1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
2acw | UPG | Glycosyltransferase | / | 0.467 | |
2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.467 | |
2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.467 | |
3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.467 | |
3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.467 | |
3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.467 | |
3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.467 | |
4foc | 0UU | ALK tyrosine kinase receptor | 2.7.10.1 | 0.467 | |
1l8a | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.466 | |
1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.466 | |
1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
2fto | TMP | Thymidylate synthase | / | 0.465 | |
2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.465 | |
2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.465 | |
2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.465 | |
3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.465 | |
3lct | ADP | ALK tyrosine kinase receptor | 2.7.10.1 | 0.465 | |
4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.465 | |
4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.465 | |
4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.465 | |
4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.465 | |
4uyf | 73B | Bromodomain-containing protein 2 | / | 0.465 | |
1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.464 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.464 | |
3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.464 | |
4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.464 | |
4lxh | C1E | Alpha/beta hydrolase fold | / | 0.464 | |
1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.463 | |
2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.463 | |
2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.463 | |
2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.463 | |
3f63 | GTX | Glutathione transferase GST1-4 | / | 0.463 | |
3tm5 | SFG | Uncharacterized protein | / | 0.463 | |
3ule | C69 | Actin-related protein 3 | / | 0.463 | |
4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.463 | |
4y3q | F02 | Endothiapepsin | 3.4.23.22 | 0.463 | |
1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
1t4u | 81A | Prothrombin | 3.4.21.5 | 0.462 | |
1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
2br5 | SAH | Cephalosporin hydroxylase CmcI | / | 0.462 | |
2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
3c4z | ADP | Rhodopsin kinase | / | 0.462 | |
3qc9 | ADP | Rhodopsin kinase | / | 0.462 | |
4o4f | ATP | Kinase | / | 0.462 | |
4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.462 | |
4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.462 | |
2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
2egl | SAH | Diphthine synthase | / | 0.461 | |
2q7v | FAD | Thioredoxin reductase | / | 0.461 | |
3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.461 | |
1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.460 | |
1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.460 | |
3pm9 | FAD | Putative oxidoreductase | / | 0.460 | |
3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.460 | |
3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.460 | |
3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.460 | |
4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.460 | |
4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.460 | |
1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.459 | |
1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.459 | |
2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.459 | |
2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.459 | |
2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.459 | |
2yex | YEX | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.459 | |
3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.459 | |
4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.459 | |
4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.459 | |
4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.459 | |
1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.458 | |
1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.458 | |
1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.458 | |
2ek4 | SAH | Diphthine synthase | / | 0.458 | |
2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.458 | |
3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.458 | |
3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.458 | |
3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.458 | |
3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.458 | |
4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.458 | |
4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.458 | |
1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.457 | |
3a7j | ADP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.457 | |
3b9l | AZZ | Serum albumin | / | 0.457 | |
3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.457 | |
3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.457 | |
3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.457 | |
4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.457 | |
4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.457 | |
4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.457 | |
4qzu | RTL | Retinol-binding protein 2 | / | 0.457 | |
4wbo | ANW | Rhodopsin kinase | / | 0.457 | |
1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.456 | |
1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.456 | |
2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.456 | |
2vtp | LZ9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.456 | |
3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.456 | |
3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.456 | |
3ixp | 834 | Ecdysone receptor | / | 0.456 | |
3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
3t8o | ATP | Rhodopsin kinase | / | 0.456 | |
4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.456 | |
4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.456 | |
1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
2bxm | IMN | Serum albumin | / | 0.455 | |
2ejk | SAH | Diphthine synthase | / | 0.455 | |
2en5 | SAH | Diphthine synthase | / | 0.455 | |
2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.455 | |
2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
2jko | BIJ | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
2p5f | SAH | Diphthine synthase | / | 0.455 | |
2r2m | I50 | Prothrombin | 3.4.21.5 | 0.455 | |
2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.455 | |
3p3z | P3Z | Putative cytochrome P450 | / | 0.455 | |
3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
3qwk | X62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.455 | |
4b1f | KRH | Glutamate racemase | / | 0.455 | |
4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.455 | |
4prv | ADP | DNA gyrase subunit B | / | 0.455 | |
5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.455 | |
1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.454 | |
1thn | ADP | Anti-sigma F factor | / | 0.454 | |
2bgi | FAD | NADPH:ferredoxin reductase | / | 0.454 | |
2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.454 | |
2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
2v00 | V15 | Endothiapepsin | 3.4.23.22 | 0.454 | |
2xvw | 9NR | Serum albumin | / | 0.454 | |
3lqf | NAD | Galactitol dehydrogenase | / | 0.454 | |
3nbw | TR4 | Ketohexokinase | / | 0.454 | |
3nlb | 5BE | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.454 | |
3psy | RB9 | Endothiapepsin | 3.4.23.22 | 0.454 | |
3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.454 | |
3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
3v8t | 477 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.454 | |
3vt5 | YI2 | Vitamin D3 receptor | / | 0.454 | |
3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.454 | |
4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.454 | |
4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.454 | |
4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.454 | |
4nmc | FAD | Bifunctional protein PutA | / | 0.454 | |
4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.454 | |
4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.454 | |
1bim | 0QB | Renin | 3.4.23.15 | 0.453 | |
1z0a | GDP | Ras-related protein Rab-2A | / | 0.453 | |
2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.453 | |
4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.453 | |
4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.453 | |
4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.453 | |
1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.452 | |
1y7u | COA | Acyl-CoA hydrolase | / | 0.452 | |
2bdy | UNB | Prothrombin | 3.4.21.5 | 0.452 | |
2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.452 | |
2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.452 | |
2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.452 | |
2pd7 | FAD | Vivid PAS protein VVD | / | 0.452 | |
2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.452 | |
3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.452 | |
3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.452 | |
3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.452 | |
4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.452 | |
4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.452 | |
4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.452 | |
4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.452 | |
4krc | AGS | Cyclin-dependent protein kinase PHO85 | 2.7.11.22 | 0.452 | |
4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.452 | |
1kfb | IGP | Tryptophan synthase alpha chain | / | 0.451 | |
1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.451 | |
1u3d | FAD | Cryptochrome-1 | / | 0.451 | |
1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.451 | |
2cjp | VPR | Epoxide hydrolase | / | 0.451 | |
2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
2ifa | FMN | Uncharacterized protein | / | 0.451 | |
2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.451 | |
2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
2pb4 | SAH | Diphthine synthase | / | 0.451 | |
2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.451 | |
3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.451 | |
3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.451 | |
4ewh | T77 | Activated CDC42 kinase 1 | / | 0.451 | |
4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.451 | |
1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.450 | |
1jtu | LYB | Thymidylate synthase | / | 0.450 | |
1qy5 | NEC | Endoplasmin | / | 0.450 | |
1zlt | HYM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
2egb | SAH | Diphthine synthase | / | 0.450 | |
2egs | SAH | Diphthine synthase | / | 0.450 | |
2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.450 | |
2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.450 | |
2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.450 | |
2vke | TAC | Tetracycline repressor protein class D | / | 0.450 | |
2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.450 | |
2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
3fp0 | FP0 | 15-O-acetyltransferase | / | 0.450 | |
3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.450 | |
3unk | 0BY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
4eiy | ZMA | Adenosine receptor A2a | / | 0.450 | |
4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.450 | |
4ug7 | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.450 | |
4uga | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.450 | |
5a3c | NAD | SIR2 family protein | / | 0.450 | |
1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.449 | |
1kzj | CB3 | Thymidylate synthase | / | 0.449 | |
1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.449 | |
1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.449 | |
1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.449 | |
1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.449 | |
1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.449 | |
1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.449 | |
2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
2i0v | 6C3 | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.449 | |
2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
2xb7 | GUI | ALK tyrosine kinase receptor | 2.7.10.1 | 0.449 | |
3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.449 | |
3id8 | MRK | Glucokinase | 2.7.1.2 | 0.449 | |
3nax | MP7 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.449 | |
4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.449 | |
4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.449 | |
4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.449 | |
4kwi | 1TJ | Reductase homolog | / | 0.449 | |
4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.449 | |
4y9r | FAD | NADPH--cytochrome P450 reductase | / | 0.449 | |
3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.449 | |
1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
1nzd | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
1r2j | FAD | FkbI | / | 0.448 | |
2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.448 | |
2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.448 | |
2eh5 | SAH | Diphthine synthase | / | 0.448 | |
2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.448 | |
3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.448 | |
3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
3gwf | FAD | Cyclohexanone monooxygenase | / | 0.448 | |
3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.448 | |
3o3j | BB4 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.448 | |
3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.448 | |
4a9m | P9M | Bromodomain-containing protein 2 | / | 0.448 | |
4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.448 | |
4egn | TWO | Cytochrome P450 | / | 0.448 | |
4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.448 | |
4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
4fx3 | 60K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
4g1z | 0VP | Vitamin D3 receptor A | / | 0.448 | |
4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.448 | |
5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.447 | |
1gqt | ACP | Ribokinase | / | 0.447 | |
1h1q | 2A6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
1u54 | ACP | Activated CDC42 kinase 1 | / | 0.447 | |
2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.447 | |
3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.447 | |
3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
3pqb | VGP | Putative oxidoreductase | / | 0.447 | |
3rdq | DTB | Streptavidin | / | 0.447 | |
3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
3zuy | TCH | Transporter | / | 0.447 | |
4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.447 | |
4aa0 | AA0 | Mitogen-activated protein kinase 14 | / | 0.447 | |
4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.447 | |
4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.447 | |
4ix6 | ADP | Uncharacterized protein | / | 0.447 | |
4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.447 | |
4ug7 | 1EV | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.447 | |
5kgp | ACO | Predicted acetyltransferase | / | 0.447 | |
1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.446 | |
1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.446 | |
2bxq | IMN | Serum albumin | / | 0.446 | |
2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.446 | |
2j2p | SC2 | Ficolin-2 | / | 0.446 | |
2pyw | ADP | Methylthioribose kinase | 2.7.1.100 | 0.446 | |
2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.446 | |
2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.446 | |
2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
2yek | EAM | Bromodomain-containing protein 2 | / | 0.446 | |
3bqr | 4RB | Death-associated protein kinase 3 | / | 0.446 | |
3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
3oqk | S52 | Renin | 3.4.23.15 | 0.446 | |
3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.446 | |
3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.446 | |
3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.446 | |
4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.446 | |
4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
4r81 | FMN | Predicted NADH dehydrogenase | / | 0.446 | |
4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.446 | |
4xx0 | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.446 | |
5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.446 | |
1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.445 | |
1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.445 | |
1xdd | AAY | Integrin alpha-L | / | 0.445 | |
2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.445 | |
2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
2dxw | SAH | Diphthine synthase | / | 0.445 | |
2e16 | SAH | Diphthine synthase | / | 0.445 | |
2izu | P01 | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.445 | |
3c4w | ATP | Rhodopsin kinase | / | 0.445 | |
3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.445 | |
3fz1 | B98 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.445 | |
3hyo | ADP | Pyridoxal kinase | / | 0.445 | |
3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.445 | |
3v5j | 0F2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.445 | |
4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.445 | |
4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.445 | |
4eom | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
4g1d | 0VK | Vitamin D3 receptor A | / | 0.445 | |
4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.445 | |
5bt5 | 2LO | Bromodomain-containing protein 2 | / | 0.445 | |
1cs4 | FOK | Adenylate cyclase type 2 | / | 0.444 | |
1cs4 | FOK | Adenylate cyclase type 5 | / | 0.444 | |
1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.444 | |
1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.444 | |
1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
2gpu | OHT | Estrogen-related receptor gamma | / | 0.444 | |
2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.444 | |
2v0u | FMN | NPH1-1 | / | 0.444 | |
2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.444 | |
2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.444 | |
3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
3iae | D7K | Benzaldehyde lyase | / | 0.444 | |
3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.444 | |
3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
3ke1 | 829 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.444 | |
3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.444 | |
3qtv | 06P | Prothrombin | 3.4.21.5 | 0.444 | |
3w0g | W07 | Vitamin D3 receptor | / | 0.444 | |
3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.444 | |
4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.444 | |
4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.444 | |
4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.444 | |
4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
4k8a | K8A | Focal adhesion kinase 1 | 2.7.10.2 | 0.444 | |
4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.444 | |
5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.444 | |
1bsv | NDP | GDP-L-fucose synthase | / | 0.443 | |
1d3d | BZT | Prothrombin | 3.4.21.5 | 0.443 | |
1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.443 | |
1tdu | DUR | Thymidylate synthase | / | 0.443 | |
1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
2cvj | FAD | Thioredoxin reductase related protein | / | 0.443 | |
2ek2 | SAH | Diphthine synthase | / | 0.443 | |
2eva | ADN | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.443 | |
2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.443 | |
2pcm | SAH | Diphthine synthase | / | 0.443 | |
2vgo | AD5 | Aurora kinase B-A | 2.7.11.1 | 0.443 | |
2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.443 | |
3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
3ll9 | ADP | Isopentenyl phosphate kinase | / | 0.443 | |
3uku | C69 | Actin-related protein 3 | / | 0.443 | |
4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.443 | |
4brx | KGW | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
4f9c | 0SX | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.443 | |
4im2 | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.443 | |
4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.443 | |
4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
4r7i | STI | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.443 | |
5dmh | ADP | 3-oxo-tetronate kinase | / | 0.443 | |
5k2a | ZMA | Adenosine receptor A2a | / | 0.443 | |
1d7a | AIR | N5-carboxyaminoimidazole ribonucleotide mutase | / | 0.442 | |
1dkf | BMS | Retinoic acid receptor alpha | / | 0.442 | |
1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.442 | |
1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.442 | |
1qoq | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.442 | |
1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
2emr | SAH | Diphthine synthase | / | 0.442 | |
2idw | 017 | Protease | / | 0.442 | |
2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.442 | |
2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.442 | |
3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.442 | |
3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.442 | |
3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.442 | |
3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.442 | |
3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.442 | |
4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.442 | |
4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.442 | |
4l8u | 9AZ | Serum albumin | / | 0.442 | |
4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.442 | |
1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.441 | |
1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
1ppj | ANY | Cytochrome b | / | 0.441 | |
1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.441 | |
1ypk | CCR | Prothrombin | 3.4.21.5 | 0.441 | |
2ay8 | 4TB | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.441 | |
2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
2e7z | MGD | Acetylene hydratase | / | 0.441 | |
2ek7 | SAH | Diphthine synthase | / | 0.441 | |
2emu | SAH | Diphthine synthase | / | 0.441 | |
2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.441 | |
2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.441 | |
2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
2ign | FAD | Pyranose 2-oxidase | / | 0.441 | |
2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.441 | |
2k62 | ITL | Fatty acid-binding protein, liver | / | 0.441 | |
2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.441 | |
2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.441 | |
3cso | XNI | Genome polyprotein | 2.7.7.48 | 0.441 | |
3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.441 | |
3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
3kq7 | KQ7 | Mitogen-activated protein kinase 14 | / | 0.441 | |
3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.441 | |
3q92 | XNB | Ketohexokinase | / | 0.441 | |
3ql8 | X01 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
3qwc | 98P | Prothrombin | 3.4.21.5 | 0.441 | |
3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.441 | |
4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.441 | |
4fkg | 4CK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.441 | |
4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
4l9q | 9TP | Serum albumin | / | 0.441 | |
4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.441 | |
4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
1c1d | NAI | Phenylalanine dehydrogenase | / | 0.440 | |
1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
1nhh | ANP | DNA mismatch repair protein MutL | / | 0.440 | |
1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.440 | |
2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
2ci0 | 1CM | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
2dek | SAH | Diphthine synthase | / | 0.440 | |
2j5b | TYE | Tyrosine--tRNA ligase | 6.1.1.1 | 0.440 | |
2owk | SAH | Diphthine synthase | / | 0.440 | |
2pca | SAH | Diphthine synthase | / | 0.440 | |
2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
2xiz | XIZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
3bbr | BHY | Glutamate receptor 2 | / | 0.440 | |
3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.440 | |
3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.440 | |
3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.440 | |
3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.440 | |
3ngl | NAP | Bifunctional protein FolD | / | 0.440 | |
3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.440 | |
3r7e | X88 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.440 | |
4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.440 | |
4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.440 | |
4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
4ffl | ADP | Uncharacterized protein | / | 0.440 | |
4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.440 | |
4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.440 | |
4nmb | FAD | Bifunctional protein PutA | / | 0.440 | |
4py6 | R78 | Bromodomain protein, putative | / | 0.440 | |
4ryv | ZEA | Protein LlR18A | / | 0.440 | |
5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.440 | |
5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 | |
5auz | GEN | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 | |
5k2b | ZMA | Adenosine receptor A2a | / | 0.440 |