sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3wiz | LC6 | Bcl-2-like protein 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3wiz | LC6 | Bcl-2-like protein 1 | / | 1.000 | |
| 3inq | X0J | Bcl-2-like protein 1 | / | 0.657 | |
| 2o2m | LI0 | Bcl-2-like protein 1 | / | 0.597 | |
| 2yxj | N3C | Bcl-2-like protein 1 | / | 0.571 | |
| 3qkd | HI0 | Bcl-2-like protein 1 | / | 0.565 | |
| 4hfn | CIY | 2-alkenal reductase (NADP(+)-dependent) | / | 0.535 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.528 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.519 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.514 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.508 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.507 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 5cuq | NSC | Genome polyprotein | / | 0.502 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.501 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.501 | |
| 3nmv | PYV | Abscisic acid receptor PYL2 | / | 0.498 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.497 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.496 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.495 | |
| 2fyu | FDN | Cytochrome b | / | 0.494 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.494 | |
| 1fkx | PRH | Adenosine deaminase | 3.5.4.4 | 0.492 | |
| 1ogx | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.492 | |
| 2pix | DHT | Androgen receptor | / | 0.492 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 1mc5 | AHE | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.491 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.491 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.490 | |
| 4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 0.489 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.488 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.487 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.485 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.485 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1efa | NPF | Lactose operon repressor | / | 0.484 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.484 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.484 | |
| 2gpu | OHT | Estrogen-related receptor gamma | / | 0.484 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 3kb0 | A8S | Abscisic acid receptor PYL2 | / | 0.483 | |
| 4c2w | ANP | Aurora kinase B-A | 2.7.11.1 | 0.482 | |
| 4ds8 | A8S | Abscisic acid receptor PYL3 | / | 0.482 | |
| 1ysi | N3B | Bcl-2-like protein 1 | / | 0.481 | |
| 2am9 | TES | Androgen receptor | / | 0.481 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.481 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.481 | |
| 2piw | DHT | Androgen receptor | / | 0.480 | |
| 4cth | RDF | Neprilysin | / | 0.480 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.479 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.479 | |
| 3qyo | Q24 | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.478 | |
| 1sre | HAB | Streptavidin | / | 0.478 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.478 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.478 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.477 | |
| 3nkt | 1HN | Gentisate 1,2-dioxygenase | / | 0.477 | |
| 4jxz | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.477 | |
| 1be4 | PCG | Nucleoside diphosphate kinase A 2 | 2.7.4.6 | 0.476 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.476 | |
| 3fzw | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.476 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.476 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.475 | |
| 2fmn | 4HF | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.475 | |
| 3ows | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.475 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.475 | |
| 4v26 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.475 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.474 | |
| 1mc0 | PCG | cGMP-dependent 3',5'-cyclic phosphodiesterase | / | 0.474 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.474 | |
| 1qtq | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.474 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.474 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.474 | |
| 3i9k | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase | 3.2.2.6 | 0.474 | |
| 4jbx | SK7 | Thymidine kinase | / | 0.474 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.473 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.473 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.473 | |
| 4f3i | 0S6 | Bromodomain-containing protein 4 | / | 0.473 | |
| 1luq | BTN | Streptavidin | / | 0.472 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.472 | |
| 1srf | MTB | Streptavidin | / | 0.472 | |
| 1xj7 | DHT | Androgen receptor | / | 0.472 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.472 | |
| 2i0v | 6C3 | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.472 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.472 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.471 | |
| 1lhu | EST | Sex hormone-binding globulin | / | 0.470 | |
| 1s1t | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 2izk | GLL | Streptavidin | / | 0.470 | |
| 2r7n | ADP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | / | 0.470 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 3akl | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.470 | |
| 3nhy | A7B | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.470 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.470 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.470 | |
| 4l7v | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.470 | |
| 4ofu | DHT | Androgen receptor | / | 0.470 | |
| 1coy | AND | Cholesterol oxidase | 1.1.3.6 | 0.469 | |
| 2piu | DHT | Androgen receptor | / | 0.469 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.469 | |
| 3nl1 | GTQ | Gentisate 1,2-dioxygenase | / | 0.469 | |
| 3t2w | BTN | Avidin/streptavidin | / | 0.469 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.468 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.468 | |
| 1td2 | PXL | Pyridoxal kinase PdxY | / | 0.468 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.468 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.468 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.468 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.467 | |
| 2nm2 | NEU | Dihydroneopterin aldolase | / | 0.467 | |
| 2qju | DSM | Na(+):neurotransmitter symporter (Snf family) | / | 0.467 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.467 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.467 | |
| 3wzn | BTN | Streptavidin | / | 0.467 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.466 | |
| 1wdk | ACO | 3-ketoacyl-CoA thiolase | / | 0.466 | |
| 2qei | CXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.466 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.466 | |
| 3hy3 | 10F | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.466 | |
| 4ear | IM5 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.466 | |
| 1fkw | PUR | Adenosine deaminase | 3.5.4.4 | 0.465 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.465 | |
| 2rtg | BTN | Streptavidin | / | 0.465 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.465 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.465 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.465 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3kb3 | A8S | Abscisic acid receptor PYL2 | / | 0.465 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.465 | |
| 3zra | ORB | Progesterone receptor | / | 0.465 | |
| 4e6a | 0O9 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 4ivq | I43 | Thymidine kinase | / | 0.465 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.465 | |
| 3gwu | SRE | Na(+):neurotransmitter symporter (Snf family) | / | 0.464 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.464 | |
| 4kfb | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
| 4oic | A8S | Bet v I allergen-like | / | 0.464 | |
| 4p5f | AR6 | Inosine-uridine nucleoside N-ribohydrolase | / | 0.464 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.463 | |
| 1pxg | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.463 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.463 | |
| 3ry2 | BTN | Streptavidin | / | 0.463 | |
| 3u8f | FGM | Ribosome inactivating protein | / | 0.463 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.463 | |
| 4nbb | 9CA | Terminal oxygenase component of carbazole | / | 0.463 | |
| 1cqs | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.462 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1qru | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.462 | |
| 1vyq | DUX | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.462 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.462 | |
| 2e40 | LGC | Beta-glucosidase 1A | 3.2.1.21 | 0.462 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.462 | |
| 2q7k | TES | Androgen receptor | / | 0.462 | |
| 2rtq | IMI | Streptavidin | / | 0.462 | |
| 2rtr | IMI | Streptavidin | / | 0.462 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.462 | |
| 3uxe | 465 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.462 | |
| 3zr7 | OR8 | Progesterone receptor | / | 0.462 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.462 | |
| 4jlt | 8PR | Cytochrome P450 2B4 | 1.14.14.1 | 0.462 | |
| 5eku | SAH | Arginine N-methyltransferase, putative | / | 0.462 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.461 | |
| 1hni | AAA | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 1kph | SAH | Cyclopropane mycolic acid synthase 1 | 2.1.1.79 | 0.461 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2bu5 | TF1 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.461 | |
| 2izl | IMI | Streptavidin | / | 0.461 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.461 | |
| 3nhw | ZXZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.461 | |
| 3vri | 1KX | HLA class I histocompatibility antigen, B-57 alpha chain | / | 0.461 | |
| 4avw | G18 | Tankyrase-2 | 2.4.2.30 | 0.461 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.460 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.460 | |
| 2vg5 | NNC | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.460 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 4gda | BTN | Streptavidin | / | 0.460 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4uga | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.460 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 4xvr | GNP | GTPase HRas | / | 0.460 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.459 | |
| 1im2 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.459 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.459 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.459 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.459 | |
| 1w1w | AGS | Structural maintenance of chromosomes protein 1 | / | 0.459 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.459 | |
| 3v0n | 4GW | Histo-blood group ABO system transferase | / | 0.459 | |
| 3w3k | L07 | Toll-like receptor 8 | / | 0.459 | |
| 3zk6 | H1I | Bcl-2-like protein 1 | / | 0.459 | |
| 1e7a | PFL | Serum albumin | / | 0.458 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.458 | |
| 1hlk | 113 | Metallo-beta-lactamase type 2 | / | 0.458 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.458 | |
| 2hxd | DUP | dCTP deaminase, dUMP-forming | 3.5.4.30 | 0.458 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.458 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.458 | |
| 4aoi | 4K0 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.458 | |
| 1eet | BFU | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 1lcw | SHM | Streptavidin | / | 0.457 | |
| 1pt5 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.457 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.457 | |
| 1x7e | 244 | Estrogen receptor | / | 0.457 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.457 | |
| 2f8p | CEI | Obelin | / | 0.457 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.457 | |
| 2q72 | IXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.457 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.457 | |
| 3cmp | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.457 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.457 | |
| 3ewd | MCF | Adenosine deaminase, putative | / | 0.457 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3gww | SFX | Na(+):neurotransmitter symporter (Snf family) | / | 0.457 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.457 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.457 | |
| 3rox | TEP | NAD(P)H-hydrate epimerase | 5.1.99.6 | 0.457 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.457 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 4fag | GTQ | Gentisate 1,2-dioxygenase | / | 0.457 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.457 | |
| 1df8 | BTN | Streptavidin | / | 0.456 | |
| 1t74 | DHT | Androgen receptor | / | 0.456 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.456 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.456 | |
| 2y67 | N21 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.456 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 3d76 | NBB | Pheromone-binding protein ASP1 | / | 0.456 | |
| 3nw4 | GTQ | Gentisate 1,2-dioxygenase | / | 0.456 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.456 | |
| 4j21 | AJ6 | Tankyrase-2 | 2.4.2.30 | 0.456 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.456 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4krc | AGS | Cyclin-dependent protein kinase PHO85 | 2.7.11.22 | 0.456 | |
| 1ga8 | UPF | LgtC | / | 0.455 | |
| 1j3j | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1rzy | 5AS | Histidine triad nucleotide-binding protein 1 | 3 | 0.455 | |
| 1tkt | H12 | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.455 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.455 | |
| 2qxx | TTP | dCTP deaminase | 3.5.4.13 | 0.455 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 3fyg | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.455 | |
| 3mec | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 3med | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.455 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.455 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.455 | |
| 4ko0 | JLJ | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 4rw6 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.454 | |
| 1dcy | I3N | Phospholipase A2, membrane associated | / | 0.454 | |
| 1e3k | R18 | Progesterone receptor | / | 0.454 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.454 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 1nd5 | 2BF | Prostatic acid phosphatase | 3.1.3.2 | 0.454 | |
| 1phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.454 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.454 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.454 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2wgg | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.454 | |
| 3bea | IXH | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.454 | |
| 3cem | AVD | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.454 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 3pdt | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.454 | |
| 3qen | 5BT | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.454 | |
| 4dlv | GNP | GTPase HRas | / | 0.454 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.454 | |
| 4rrq | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.454 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1enp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.453 | |
| 1eqb | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.453 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.453 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.453 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.453 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.453 | |
| 2p1d | SAH | Genome polyprotein | 2.7.7.48 | 0.453 | |
| 2pkl | DHT | Androgen receptor | / | 0.453 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.453 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.453 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3h5s | H5S | Genome polyprotein | 2.7.7.48 | 0.453 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.453 | |
| 3qji | MGP | Ribosome inactivating protein | / | 0.453 | |
| 4c9w | VGH | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.453 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.453 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.453 | |
| 4hlm | 16S | Tankyrase-2 | 2.4.2.30 | 0.453 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.453 | |
| 4j3i | 1K0 | Bromodomain-containing protein 4 | / | 0.453 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.453 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.453 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.452 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.452 | |
| 1t73 | DHT | Androgen receptor | / | 0.452 | |
| 2b96 | ANN | Phospholipase A2 | 3.1.1.4 | 0.452 | |
| 2chl | DKI | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.452 | |
| 2qds | MCO | Metallo-beta-lactamase type 2 | / | 0.452 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.452 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.452 | |
| 3g07 | SAM | 7SK snRNA methylphosphate capping enzyme | 2.1.1 | 0.452 | |
| 3kxo | KXO | Hematopoietic prostaglandin D synthase | / | 0.452 | |
| 3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.452 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4dne | DTB | Streptavidin | / | 0.452 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.452 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.451 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.451 | |
| 1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.451 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.451 | |
| 1kzi | THG | Thymidylate synthase | / | 0.451 | |
| 1qv0 | CZH | Obelin | / | 0.451 | |
| 1t76 | DHT | Androgen receptor | / | 0.451 | |
| 1wbb | ADP | DNA mismatch repair protein MutS | / | 0.451 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.451 | |
| 2j7c | IDE | Beta-glucosidase A | 3.2.1.21 | 0.451 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.451 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.451 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
| 2xnm | WGZ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
| 3cfo | GMP | DNA-directed DNA polymerase | / | 0.451 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.451 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3up0 | D7S | aceDAF-12 | / | 0.451 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.451 | |
| 4cvb | PQQ | Alcohol dehydrogenase | / | 0.451 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 1hnv | TBO | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.450 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.450 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.450 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.450 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.450 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.450 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.450 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.450 | |
| 3rga | ILD | Epoxide hydrolase LasB | 5.5.1 | 0.450 | |
| 3roe | THM | NAD(P)H-hydrate epimerase | 5.1.99.6 | 0.450 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.450 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.450 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.450 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.450 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 4dso | GSP | GTPase KRas | / | 0.450 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 4jyz | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.450 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1e2n | RCA | Thymidine kinase | / | 0.449 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.449 | |
| 1g8o | U5P | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.449 | |
| 1rt7 | UC4 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.449 | |
| 1xxj | UNC | Uricase | 1.7.3.3 | 0.449 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.449 | |
| 2opq | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.449 | |
| 2uza | HTL | Pyruvate synthase | / | 0.449 | |
| 2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.449 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.449 | |
| 3bcd | ACX | Alpha amylase | / | 0.449 | |
| 3bmn | AX3 | Pteridine reductase | / | 0.449 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3erd | DES | Estrogen receptor | / | 0.449 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3h24 | B55 | Dihydropteroate synthase | / | 0.449 | |
| 3pd5 | TSB | Threonine--tRNA ligase | 6.1.1.3 | 0.449 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.449 | |
| 4f1t | H52 | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.449 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.449 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4nyj | GNP | GTPase HRas | / | 0.449 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.449 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.449 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 1jlq | SBN | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.448 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.448 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.448 | |
| 3l03 | 4OH | Estrogen receptor | / | 0.448 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.448 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4at2 | ASD | Possible succinate dehydrogenase | / | 0.448 | |
| 4c66 | H4C | Bromodomain-containing protein 4 | / | 0.448 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.448 | |
| 4id5 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.448 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 4lwx | MU2 | Ribosome inactivating protein | / | 0.448 | |
| 4rw4 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.447 | |
| 1n0u | SO1 | Elongation factor 2 | / | 0.447 | |
| 1nja | DCM | Thymidylate synthase | / | 0.447 | |
| 1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.447 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.447 | |
| 2aj8 | SC3 | Dipeptidyl peptidase 4 | / | 0.447 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 2pio | DHT | Androgen receptor | / | 0.447 | |
| 2pxa | SAH | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 2w8y | 486 | Progesterone receptor | / | 0.447 | |
| 2xno | ED8 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.447 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.447 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.447 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.447 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4bmp | FMN | Protein NrdI | / | 0.447 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.447 | |
| 4j3l | AJ5 | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.447 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4twl | ASC | Dioscorin 5 | / | 0.447 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.447 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.446 | |
| 1gwr | EST | Estrogen receptor | / | 0.446 | |
| 2bu7 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.446 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.446 | |
| 2jkc | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.446 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.446 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.446 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.446 | |
| 2qzs | ADP | Glycogen synthase | 2.4.1.21 | 0.446 | |
| 2rtm | IMI | Streptavidin | / | 0.446 | |
| 2rtn | IMI | Streptavidin | / | 0.446 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.446 | |
| 3i58 | 7NA | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.446 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3kdj | A8S | Abscisic acid receptor PYL1 | / | 0.446 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3lth | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 3m8c | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.446 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.446 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4dlz | GNP | GTPase HRas | / | 0.446 | |
| 5alu | HD2 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.446 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.446 | |
| 1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.445 | |
| 1fls | WAY | Collagenase 3 | 3.4.24 | 0.445 | |
| 1g60 | SAM | Modification methylase MboII | 2.1.1.72 | 0.445 | |
| 1giq | NAI | Iota toxin component Ia | / | 0.445 | |
| 1gwq | ZTW | Estrogen receptor | / | 0.445 | |
| 1kt5 | RTL | Retinol-binding protein 4 | / | 0.445 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.445 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 2apc | UDM | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.445 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.445 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 2j7d | GI1 | Beta-glucosidase A | 3.2.1.21 | 0.445 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.445 | |
| 2q7l | TES | Androgen receptor | / | 0.445 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.445 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.445 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.445 | |
| 3a27 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.445 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3owy | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.445 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.445 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4bmo | FMN | Protein NrdI | / | 0.445 | |
| 4iix | 1EG | Microcin C7 self-immunity protein MccF | / | 0.445 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.445 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.445 | |
| 5hgc | HCY | Uncharacterized protein | / | 0.445 | |
| 10mh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.444 | |
| 1ddt | APU | Diphtheria toxin | / | 0.444 | |
| 1e7w | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 1lhn | AON | Sex hormone-binding globulin | / | 0.444 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 1xuz | MMN | Capsule biosynthesis protein | / | 0.444 | |
| 1zs6 | ADP | Nucleoside diphosphate kinase 3 | 2.7.4.6 | 0.444 | |
| 2ada | HPR | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2izh | BTN | Streptavidin | / | 0.444 | |
| 2izj | BTN | Streptavidin | / | 0.444 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 2q6h | CXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.444 | |
| 2rtk | GLL | Streptavidin | / | 0.444 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 2yhu | WHF | Pteridine reductase | / | 0.444 | |
| 2ylp | TES | Androgen receptor | / | 0.444 | |
| 3b5i | SAH | Indole-3-acetate O-methyltransferase 1 | / | 0.444 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.444 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3jq7 | DX2 | Pteridine reductase, putative | / | 0.444 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 3tl1 | JRO | Putative polyketide cyclase | / | 0.444 | |
| 3zns | NU7 | Histone deacetylase 7 | 3.5.1.98 | 0.444 | |
| 4ai8 | DZA | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.444 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.444 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.444 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.444 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.444 | |
| 4meo | 25V | Bromodomain-containing protein 4 | / | 0.444 | |
| 4mrx | CZH | Obelin | / | 0.444 | |
| 4oed | DHT | Androgen receptor | / | 0.444 | |
| 4q4e | BB2 | Aminopeptidase N | 3.4.11.2 | 0.444 | |
| 4rr9 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.444 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.444 | |
| 1jjt | BDS | Beta-lactamase | / | 0.443 | |
| 1l2i | ETC | Estrogen receptor | / | 0.443 | |
| 1mk5 | BTN | Streptavidin | / | 0.443 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.443 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1t7t | DHT | Androgen receptor | / | 0.443 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.443 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.443 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.443 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2vbv | FMN | Riboflavin kinase | 2.7.1.161 | 0.443 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.443 | |
| 3evb | SAH | Genome polyprotein | 2.1.1.56 | 0.443 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3lmh | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.443 | |
| 3m0e | ATP | Transcriptional regulator (NtrC family) | / | 0.443 | |
| 3qzy | FAD | FAD-linked sulfhydryl oxidase | / | 0.443 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.443 | |
| 4bw1 | S5B | Bromodomain-containing protein 4 | / | 0.443 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.443 | |
| 4eom | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.442 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1jlc | FTC | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1s1w | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.442 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.442 | |
| 1w2c | ANP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.442 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.442 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.442 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.442 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.442 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.442 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2hl3 | GLU_GLU_TYR | Dynactin subunit 1 | / | 0.442 | |
| 2y3f | BTN | Streptavidin | / | 0.442 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 3dz2 | A8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.442 | |
| 3hf6 | LX0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.442 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3k90 | A8S | Abscisic acid receptor PYR1 | / | 0.442 | |
| 3kpj | SAH | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.442 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.442 | |
| 4dlx | GNP | GTPase HRas | / | 0.442 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4zn7 | DES | Estrogen receptor | / | 0.442 | |
| 4zs4 | ATP | Myosin heavy chain kinase A | 2.7.11.7 | 0.442 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.442 | |
| 1b8n | IMG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.441 | |
| 1it7 | GUN | tRNA-guanine(15) transglycosylase | 2.4.2.48 | 0.441 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 1mc1 | PCX | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.441 | |
| 1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.441 | |
| 1u3g | THF | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.441 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2hnd | NVP | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 2piv | DHT | Androgen receptor | / | 0.441 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.441 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2z4j | DHT | Androgen receptor | / | 0.441 | |
| 3cmp | EB4 | Neutrophil gelatinase-associated lipocalin | / | 0.441 | |
| 3hv7 | 1AU | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.441 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.441 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 3tpt | ADP | Serine/threonine-protein kinase toxin HipA | / | 0.441 | |
| 3w8z | HTK | Putative FAD-dependent oxygenase EncM | / | 0.441 | |
| 4b6r | 3DQ | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.441 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.441 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.441 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4i9q | XG4 | DNA-directed DNA polymerase | / | 0.441 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.441 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.441 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1oho | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.440 | |
| 1q6y | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.440 | |
| 1rfu | PLP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.440 | |
| 2b1i | 93A | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.440 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2c5l | GTP | GTPase HRas | / | 0.440 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.440 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.440 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.440 | |
| 2yja | EST | Estrogen receptor | / | 0.440 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.440 | |
| 3cse | N22 | Uncharacterized protein | / | 0.440 | |
| 3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.440 | |
| 3kqj | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.440 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.440 | |
| 4buv | 16I | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.440 | |
| 4f79 | P53 | Putative phospho-beta-glucosidase | / | 0.440 | |
| 4gqe | 6KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 4hl5 | 15W | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4m0l | GDP | Translation initiation factor 2 subunit gamma | / | 0.440 | |
| 4uga | Q05 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.440 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.440 |