sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3wd9	QPC	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3wd9	QPC	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	1.000
3w5e	NVW	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.601
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.501
3g4g	D71	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.496
4myq	19T	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.482
3g45	988	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.481
1tbb	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.480
3sl6	JN8	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.473
3tvx	PNX	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	3.1.4.53	0.472
3sl8	JN7	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.445
4kp6	1S1	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.442