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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3w2nRODDihydroorotate dehydrogenase (fumarate)1.3.98.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3w2nRODDihydroorotate dehydrogenase (fumarate)1.3.98.11.000
3w1tWRODihydroorotate dehydrogenase (fumarate)1.3.98.10.624
3w1rMRODihydroorotate dehydrogenase (fumarate)1.3.98.10.605
3w2uROUDihydroorotate dehydrogenase (fumarate)1.3.98.10.545
3w2mZRODihydroorotate dehydrogenase (fumarate)1.3.98.10.539
3w3oROEDihydroorotate dehydrogenase (fumarate)1.3.98.10.486
3w1xXRODihydroorotate dehydrogenase (fumarate)1.3.98.10.473
3w1qYRODihydroorotate dehydrogenase (fumarate)1.3.98.10.472
3w2jQRODihydroorotate dehydrogenase (fumarate)1.3.98.10.469
3w233RODihydroorotate dehydrogenase (fumarate)1.3.98.10.464