sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3vs0	VS0	Tyrosine-protein kinase HCK	2.7.10.2

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3vs0	VS0	Tyrosine-protein kinase HCK	2.7.10.2	1.000
3vrz	VRZ	Tyrosine-protein kinase HCK	2.7.10.2	0.531
3vs2	VSB	Tyrosine-protein kinase HCK	2.7.10.2	0.519
3vs1	VSA	Tyrosine-protein kinase HCK	2.7.10.2	0.511
3vs5	VSG	Tyrosine-protein kinase HCK	2.7.10.2	0.507
2c0i	L1G	Tyrosine-protein kinase HCK	2.7.10.2	0.478
1qcf	PP1	Tyrosine-protein kinase HCK	2.7.10.2	0.459
1ad5	ANP	Tyrosine-protein kinase HCK	2.7.10.2	0.455
2h8h	H8H	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.444