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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3vryB43Tyrosine-protein kinase HCK2.7.10.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3vryB43Tyrosine-protein kinase HCK2.7.10.21.000
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.643
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.634
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.620
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.608
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.608
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.599
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.592
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.588
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.587
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.584
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.584
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.579
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.576
3vs1VSATyrosine-protein kinase HCK2.7.10.20.574
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.573
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.571
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.570
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.555
4i22IREEpidermal growth factor receptor2.7.10.10.552
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.545
4hjoAQ4Epidermal growth factor receptor2.7.10.10.544
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.540
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.538
4nka2K7Fibroblast growth factor receptor 1/0.538
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.536
4y93746Tyrosine-protein kinase/0.535
1xkkFMMEpidermal growth factor receptor2.7.10.10.531
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.529
3w33W19Epidermal growth factor receptor2.7.10.10.528
4gmy0X5Tyrosine-protein kinase JAK2/0.527
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.525
2of2547Tyrosine-protein kinase Lck2.7.10.20.523
2hk51BMTyrosine-protein kinase HCK2.7.10.20.520
4yuqKS1Calmodulin-like domain protein kinase/0.519
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.518
5aaaVGHALK tyrosine kinase receptor2.7.10.10.518
5e8wSTUTGF-beta receptor type-12.7.11.300.517
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.516
1bygSTUTyrosine-protein kinase CSK/0.515
3poz03PEpidermal growth factor receptor2.7.10.10.515
3w2sW2REpidermal growth factor receptor2.7.10.10.515
2wotZZGTGF-beta receptor type-12.7.11.300.514
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.511
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.507
4gk2L66Ephrin type-A receptor 32.7.10.10.506
1u4dDBQActivated CDC42 kinase 1/0.503
2of4979Tyrosine-protein kinase Lck2.7.10.20.503
2gs7ANPEpidermal growth factor receptor2.7.10.10.502
2henADPEphrin type-B receptor 22.7.10.10.502
4c02TAKActivin receptor type-12.7.11.300.502
4j97ACPFibroblast growth factor receptor 2/0.502
4riyADPEpidermal growth factor receptor2.7.10.10.502
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.500
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.500
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.500
4zseANPEpidermal growth factor receptor2.7.10.10.499
1rw8580TGF-beta receptor type-12.7.11.300.498
2py3ACPFibroblast growth factor receptor 2/0.498
4hvh19RTyrosine-protein kinase JAK32.7.10.20.497
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.497
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.496
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.495
3a60STURibosomal protein S6 kinase beta-12.7.11.10.495
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.495
3gxlQIGTGF-beta receptor type-12.7.11.300.494
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.494
2itnANPEpidermal growth factor receptor2.7.10.10.493
2pzpACPFibroblast growth factor receptor 2/0.493
3l8p0CEAngiopoietin-1 receptor2.7.10.10.493
2itqITQEpidermal growth factor receptor2.7.10.10.492
3w18N13Aurora kinase A2.7.11.10.492
4g170VNCasein kinase I isoform gamma-32.7.11.10.492
4gk4L90Ephrin type-A receptor 32.7.10.10.492
2qo9ANPEphrin type-A receptor 32.7.10.10.491
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.490
3r9dX6BCyclin-dependent kinase 22.7.11.220.490
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.490
4riyANPReceptor tyrosine-protein kinase erbB-32.7.10.10.490
1u54ACPActivated CDC42 kinase 1/0.489
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.489
3oriAGSSerine/threonine protein kinase/0.488
4bb432WEphrin type-B receptor 42.7.10.10.488
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.488
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.488
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.487
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.487
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.486
4kiq1RAMitogen-activated protein kinase 14/0.486
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.486
5e8xSTUTGF-beta receptor type-12.7.11.300.486
2vwz7X6Ephrin type-B receptor 42.7.10.10.485
3aoxEMHALK tyrosine kinase receptor2.7.10.10.485
4c62XWWTyrosine-protein kinase JAK2/0.485
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.484
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.484
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.484
4iebANPCalmodulin-domain protein kinase 1/0.484
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.484
2vx17X8Ephrin type-B receptor 42.7.10.10.483
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.483
3uvqFS8Mitogen-activated protein kinase 14/0.483
4hvg19QTyrosine-protein kinase JAK32.7.10.20.483
3oom507Activin receptor type-12.7.11.300.482
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.482
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.482
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.481
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.481
2vwx7X4Ephrin type-B receptor 42.7.10.10.481
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.481
3oroAGSSerine/threonine protein kinase/0.481
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.481
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.481
2g2fAGSTyrosine-protein kinase ABL12.7.10.20.480
4fob0USALK tyrosine kinase receptor2.7.10.10.480
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.480
2yfxVGHALK tyrosine kinase receptor2.7.10.10.479
3gubGUBDeath-associated protein kinase 12.7.11.10.479
3ttjJBIMitogen-activated protein kinase 102.7.11.240.479
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.479
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.478
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.478
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.478
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.478
4gk3L87Ephrin type-A receptor 32.7.10.10.478
2vwu7X1Ephrin type-B receptor 42.7.10.10.477
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.477
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.477
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.477
4g1wG1WMitogen-activated protein kinase 82.7.11.240.477
2c6eHPMAurora kinase A2.7.11.10.476
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.476
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.476
4y95746Tyrosine-protein kinase/0.476
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.476
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.475
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.475
3ac2KSETyrosine-protein kinase Lck2.7.10.20.474
2xa4AZ5Tyrosine-protein kinase JAK2/0.473
3l9hEMQKinesin-like protein KIF11/0.473
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.473
4ansVGHALK tyrosine kinase receptor2.7.10.10.473
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.473
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.472
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.472
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.472
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.472
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.471
2balPQAMitogen-activated protein kinase 14/0.471
2vwy7X5Ephrin type-B receptor 42.7.10.10.471
2yn8STUEphrin type-B receptor 42.7.10.10.471
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.471
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.471
4nks2M2Fibroblast growth factor receptor 1/0.471
1ir3ANPInsulin receptor2.7.10.10.470
2pz5ACPFibroblast growth factor receptor 2/0.470
4c4h7RODual specificity protein kinase TTK2.7.12.10.470
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.470
4f630S7Fibroblast growth factor receptor 1/0.469
4g2fC07Ephrin type-A receptor 32.7.10.10.469
4nk92K5Fibroblast growth factor receptor 1/0.469
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.468
2xp2VGHALK tyrosine kinase receptor2.7.10.10.468
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.468
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.468
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.467
2pwlACPFibroblast growth factor receptor 2/0.467
2r64740Cyclin-dependent kinase 22.7.11.220.467
4e4m0NHTyrosine-protein kinase JAK2/0.467
4ic7ANPMitogen-activated protein kinase 72.7.11.240.467
4ih8B43Calmodulin-domain protein kinase 1/0.467
1uyhPU0Heat shock protein HSP 90-alpha/0.466
2wecPP5Penicillopepsin-13.4.23.200.466
3b7dCNIGlutamate receptor 2/0.466
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.466
4anqVGHALK tyrosine kinase receptor2.7.10.10.466
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.466
4erwSTUCyclin-dependent kinase 22.7.11.220.466
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.466
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.466
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.466
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
1xddAAYIntegrin alpha-L/0.465
2xyuQ9GEphrin type-A receptor 42.7.10.10.465
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.465
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.465
3gc9B45Mitogen-activated protein kinase 112.7.11.240.465
3hx4ANPCalmodulin-domain protein kinase 1/0.465
3mvl38PMitogen-activated protein kinase 14/0.465
3zewSTUEphrin type-B receptor 42.7.10.10.465
2zybKSLTyrosine-protein kinase Lck2.7.10.20.464
3ormAGSSerine/threonine protein kinase/0.464
4aa4QC0Mitogen-activated protein kinase 14/0.464
4c4g7RODual specificity protein kinase TTK2.7.12.10.464
4id71G0Activated CDC42 kinase 1/0.464
1jpaANPEphrin type-B receptor 22.7.10.10.463
2y6o1N1Ephrin type-A receptor 42.7.10.10.463
3b2tM33Fibroblast growth factor receptor 2/0.463
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.463
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.462
3r9hZ67Cyclin-dependent kinase 22.7.11.220.462
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.462
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.462
1c6yMK1Protease/0.461
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.461
2vww7X2Ephrin type-B receptor 42.7.10.10.461
3h0aD30Peroxisome proliferator-activated receptor gamma/0.461
4a6bQG8Gag-Pol polyprotein3.4.23.160.461
4c61LMMTyrosine-protein kinase JAK2/0.461
5e92ANPTGF-beta receptor type-22.7.11.300.461
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.460
1xjdSTUProtein kinase C theta type2.7.11.130.460
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.460
4cd0AWJALK tyrosine kinase receptor2.7.10.10.460
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.460
1fwkADPHomoserine kinase2.7.1.390.459
2itzIREEpidermal growth factor receptor2.7.10.10.459
3nbwTR4Ketohexokinase/0.459
3qlrNDPDihydrofolate reductase1.5.1.30.459
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.459
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.459
4wkqIREEpidermal growth factor receptor2.7.10.10.459
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.459
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.458
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.458
2ittAEEEpidermal growth factor receptor2.7.10.10.458
2izrBRKCasein kinase I isoform gamma-32.7.11.10.458
2qocANPEphrin type-A receptor 32.7.10.10.458
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.458
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.458
3pe6ZYHMonoglyceride lipase/0.458
3uleC69Actin-related protein 3/0.458
3upjU03Gag-Pol polyprotein/0.458
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.458
4qmpDKISerine/threonine-protein kinase 242.7.11.10.458
2xikJ60Serine/threonine-protein kinase 252.7.11.10.457
4jbpYPHAurora kinase A2.7.11.10.457
4kip1R9Mitogen-activated protein kinase 14/0.457
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.456
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.456
3tm5SFGUncharacterized protein/0.456
4an35Y0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.456
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.456
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.456
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.456
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.456
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.456
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.455
3icrCOACoenzyme A disulfide reductase/0.455
3t8oATPRhodopsin kinase/0.455
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.455
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.455
4fod0UVALK tyrosine kinase receptor2.7.10.10.455
4hgs15GCasein kinase I isoform gamma-32.7.11.10.455
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.455
4oavACP2-5A-dependent ribonuclease3.1.260.455
5aacVGHALK tyrosine kinase receptor2.7.10.10.455
1i8tFADUDP-galactopyranose mutase5.4.99.90.454
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.454
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.454
2excJNKMitogen-activated protein kinase 102.7.11.240.454
2fgiPD1Fibroblast growth factor receptor 1/0.454
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.454
2vx07X7Ephrin type-B receptor 42.7.10.10.454
2znpK55Peroxisome proliferator-activated receptor delta/0.454
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.454
3nwxKVSGag-Pol polyprotein3.4.23.160.454
3q5iANPProtein kinase, putative/0.454
4aotGW8Serine/threonine-protein kinase 102.7.11.10.454
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.454
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.454
5uviZMAAdenosine receptor A2a/0.454
2c475IDCasein kinase I isoform gamma-2/0.453
2h96893Mitogen-activated protein kinase 82.7.11.240.453
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.453
2uzlC94Cyclin-dependent kinase 22.7.11.220.453
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.453
2zb0GK3Mitogen-activated protein kinase 14/0.453
2znq401Peroxisome proliferator-activated receptor delta/0.453
3a7hATPSerine/threonine-protein kinase 242.7.11.10.453
3w2rW2REpidermal growth factor receptor2.7.10.10.453
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.453
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.453
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.452
2znnS44Peroxisome proliferator-activated receptor alpha/0.452
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3erkSB4Mitogen-activated protein kinase 12.7.11.240.452
3hllI45Mitogen-activated protein kinase 14/0.452
3mnrSD1Heat shock protein HSP 90-alpha/0.452
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.452
3s4qNK0Mitogen-activated protein kinase 14/0.452
3v3vMYUMitogen-activated protein kinase 82.7.11.240.452
3vjoANPEpidermal growth factor receptor2.7.10.10.452
4aa5NQBMitogen-activated protein kinase 14/0.452
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.452
4hnf16WCasein kinase I isoform delta2.7.11.10.452
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.452
1bdlIM1Gag-Pol polyprotein3.4.23.160.451
1jld0PPGag-Pol polyprotein/0.451
2v7a627Tyrosine-protein kinase ABL12.7.10.20.451
2w05FRTCyclin-dependent kinase 22.7.11.220.451
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.451
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.451
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3gggNADPrephenate dehydrogenase/0.451
3gstGPRGlutathione S-transferase Mu 12.5.1.180.451
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.451
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.451
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.451
1di8DTQCyclin-dependent kinase 22.7.11.220.450
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3ctj320Hepatocyte growth factor receptor2.7.10.10.450
3ds6A17Mitogen-activated protein kinase 14/0.450
3iphG11Mitogen-activated protein kinase 14/0.450
4aw530KEphrin type-B receptor 42.7.10.10.450
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.450
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.450
2uy0HV1Gag-Pol polyprotein3.4.23.160.449
2w1hL0FCyclin-dependent kinase 22.7.11.220.449
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.449
4gu94GUFocal adhesion kinase 12.7.10.20.449
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.449
4pd6URINucleoside permease/0.449
4tuvCPZCytochrome P450 1191.140.449
5awmANPStress-activated protein kinase JNK2.7.11.240.449
2fdd385Pol protein/0.448
2i40BLZCyclin-dependent kinase 22.7.11.220.448
2itpAEEEpidermal growth factor receptor2.7.10.10.448
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.448
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.448
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3hz137DHeat shock protein HSP 90-alpha/0.448
3s1dZIRCytokinin dehydrogenase 11.5.99.120.448
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.448
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.448
4eoi1ROCyclin-dependent kinase 22.7.11.220.448
4ewhT77Activated CDC42 kinase 1/0.448
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.448
4loqSB4Mitogen-activated protein kinase 14/0.448
2aa0MTPAdenosine kinase2.7.1.200.447
2bfyH1NAurora kinase B-A2.7.11.10.447
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.447
2izsBRQCasein kinase I isoform gamma-32.7.11.10.447
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.447
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.447
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
3l8xN4DMitogen-activated protein kinase 14/0.447
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.447
3slkNDPPolyketide synthase extender module 2/0.447
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.447
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.447
4xldBRLPeroxisome proliferator-activated receptor gamma/0.447
1cdeGARPhosphoribosylglycinamide formyltransferase/0.446
1gih1PUCyclin-dependent kinase 22.7.11.220.446
1hiiC20Gag-Pol polyprotein/0.446
1osvCHCBile acid receptor/0.446
1wbk568Pol protein/0.446
1xq6NAPUncharacterized protein At5g02240/0.446
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2k62ITLFatty acid-binding protein, liver/0.446
3fklFKLMitogen-activated protein kinase 14/0.446
3kddJZQGag-Pol polyprotein3.4.23.160.446
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.446
4f640S8Fibroblast growth factor receptor 1/0.446
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.446
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4jq7KJQEpidermal growth factor receptor2.7.10.10.446
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.446
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.446
4nj32KDCyclin-dependent kinase 22.7.11.220.446
4y8wSTRSteroid 21-hydroxylase/0.446
3qakUKAAdenosine receptor A2a/0.446
1q1wFADPutidaredoxin reductase1.18.1.50.445
1qxlFR8Adenosine deaminase3.5.4.40.445
1w1rZEACytokinin dehydrogenase 11.5.99.120.445
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
2j3kNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.445
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.445
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.445
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.445
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.445
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.445
3x2fNAIAdenosylhomocysteinase/0.445
4an92P7Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.445
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.445
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.445
1l3iSAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)/0.444
1ml6GBXGlutathione S-transferase A22.5.1.180.444
2eb3ANPEpidermal growth factor receptor2.7.10.10.444
2q4bNAPUncharacterized protein At5g02240/0.444
2w1eL0EAurora kinase A2.7.11.10.444
2zjaACPATP-dependent DNA helicase Hel308/0.444
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.444
3ogqAB1Pol polyprotein/0.444
3sacAF8Protease/0.444
3tqhNDPQuinone oxidoreductase/0.444
3wmxNADNAD dependent epimerase/dehydratase/0.444
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.444
4fnyI3KALK tyrosine kinase receptor2.7.10.10.444
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.444
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.444
4i02CMPcAMP-activated global transcriptional regulator CRP/0.444
4jldADPAdenylate kinase/0.444
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.444
4qms1N1Serine/threonine-protein kinase 242.7.11.10.444
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1uyrD1LAcetyl-CoA carboxylase/0.443
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.443
2vgoAD5Aurora kinase B-A2.7.11.10.443
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.443
3ac1KZITyrosine-protein kinase Lck2.7.10.20.443
3cwkREACellular retinoic acid-binding protein 2/0.443
3gi6D78Gag-Pol polyprotein/0.443
3inxJZCHeat shock protein HSP 90-alpha/0.443
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.443
3t1tGDPProbable gliding protein mglA/0.443
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.443
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.443
4lxhC1EAlpha/beta hydrolase fold/0.443
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
1cm8ANPMitogen-activated protein kinase 12/0.442
1ja0NAPNADPH--cytochrome P450 reductase/0.442
1mesDMPGag-Pol polyprotein3.4.23.160.442
1oecAA2Fibroblast growth factor receptor 2/0.442
2cig1DGDihydrofolate reductase1.5.1.30.442
2hog710Serine/threonine-protein kinase Chk12.7.11.10.442
2iw84SPCyclin-dependent kinase 22.7.11.220.442
2jd0NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.442
2o0uC0MMitogen-activated protein kinase 102.7.11.240.442
2pvyACPFibroblast growth factor receptor 2/0.442
2pzrACPFibroblast growth factor receptor 2/0.442
2yjxYJXHeat shock protein HSP 90-alpha/0.442
3cqeP91Wee1-like protein kinase2.7.10.20.442
3hz5Z64Heat shock protein HSP 90-alpha/0.442
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.442
4gt3ATPMitogen-activated protein kinase 12.7.11.240.442
4jia1K3Tyrosine-protein kinase JAK2/0.442
4l49CAMCamphor 5-monooxygenase1.14.15.10.442
4zohFADPutative oxidoreductase FAD-binding subunit/0.442
5iubCLRAdenosine receptor A2a/0.442
1bdrIM1Gag-Pol polyprotein3.4.23.160.441
1e9hINRCyclin-dependent kinase 22.7.11.220.441
1k7l544Peroxisome proliferator-activated receptor alpha/0.441
1pkdUCNCyclin-dependent kinase 22.7.11.220.441
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.441
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.441
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.441
1ywrLI9Mitogen-activated protein kinase 14/0.441
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.441
2wpxACOOrf14/0.441
3dxjNE6DNA-directed RNA polymerase subunit beta/0.441
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.441
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.441
3ns2PYVAbscisic acid receptor PYL2/0.441
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.441
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.441
4g160VMCasein kinase I isoform gamma-32.7.11.10.441
4hge15VTyrosine-protein kinase JAK2/0.441
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.441
4ysjADPCalmodulin-like domain protein kinase/0.441
5a3cNADSIR2 family protein/0.441
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
5k2dZMAAdenosine receptor A2a/0.441
1d4iBEGGag-Pol polyprotein3.4.23.160.440
1hvrXK2Gag-Pol polyprotein/0.440
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.440
1me8RVPInosine-5'-monophosphate dehydrogenase/0.440
1meiXMPInosine-5'-monophosphate dehydrogenase/0.440
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.440
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.440
2g1r3IGRenin3.4.23.150.440
2om9AJAPeroxisome proliferator-activated receptor gamma/0.440
2qbnCAMCamphor 5-monooxygenase1.14.15.10.440
2ykiYKIHeat shock protein HSP 90-alpha/0.440
3acjKSSTyrosine-protein kinase Lck2.7.10.20.440
3bgrT27Gag-Pol polyprotein2.7.7.490.440
3kf7L9GMitogen-activated protein kinase 14/0.440
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.440
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.440
3nbvANPKetohexokinase/0.440
3oafOAGDihydrofolate reductase1.5.1.30.440
3s43478Protease/0.440
3vquO22Dual specificity protein kinase TTK2.7.12.10.440
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.440
4hgt15GCasein kinase I isoform delta2.7.11.10.440
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.440
4l4dCAMCamphor 5-monooxygenase1.14.15.10.440
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.440