sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3vr8	RQX	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3vr8	RQX	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	/	1.000
3vr8	RQX	Cytochrome b-large subunit	/	1.000
3vrb	FTN	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	/	0.589
3vrb	FTN	Cytochrome b-large subunit	/	0.589
5c3j	UQ1	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	/	0.580
5c3j	UQ1	Succinate dehydrogenase cytochrome b560	/	0.580
3ae4	N1M	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	1.3.5.1	0.465
3ae4	N1M	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial	/	0.465
2wp9	CBE	Succinate dehydrogenase iron-sulfur subunit	1.3.5.1	0.456
2wp9	CBE	Succinate dehydrogenase cytochrome b556 subunit	/	0.456