sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3vnt	0JA	Vascular endothelial growth factor receptor 2	2.7.10.1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3vnt	0JA	Vascular endothelial growth factor receptor 2	2.7.10.1	1.000
2qu6	857	Vascular endothelial growth factor receptor 2	2.7.10.1	0.556
3cp9	C19	Vascular endothelial growth factor receptor 2	2.7.10.1	0.515
4ase	AV9	Vascular endothelial growth factor receptor 2	2.7.10.1	0.502
3hng	8ST	Vascular endothelial growth factor receptor 1	2.7.10.1	0.489
2hyy	STI	Tyrosine-protein kinase ABL1	2.7.10.2	0.482
3b8q	900	Vascular endothelial growth factor receptor 2	2.7.10.1	0.479
1iep	STI	Tyrosine-protein kinase ABL1	2.7.10.2	0.473
3c7q	XIN	Vascular endothelial growth factor receptor 2	2.7.10.1	0.471
3vhk	BPK	Vascular endothelial growth factor receptor 2	2.7.10.1	0.469
3efl	706	Vascular endothelial growth factor receptor 2	2.7.10.1	0.466
3dtw	A96	Vascular endothelial growth factor receptor 2	2.7.10.1	0.463
2xir	00J	Vascular endothelial growth factor receptor 2	2.7.10.1	0.455
4c8b	0LI	Receptor-interacting serine/threonine-protein kinase 2	2.7.11.1	0.447