sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3vid	4TT	Vascular endothelial growth factor receptor 2	2.7.10.1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3vid	4TT	Vascular endothelial growth factor receptor 2	2.7.10.1	1.000
3c7q	XIN	Vascular endothelial growth factor receptor 2	2.7.10.1	0.501
3vnt	0JA	Vascular endothelial growth factor receptor 2	2.7.10.1	0.475
3tub	FPU	Tyrosine-protein kinase SYK	2.7.10.2	0.458
4qrc	0LI	Fibroblast growth factor receptor 4	2.7.10.1	0.454
3vrz	VRZ	Tyrosine-protein kinase HCK	2.7.10.2	0.449
1zth	ADP	RIO-type serine/threonine-protein kinase Rio1	2.7.11.1	0.447
3b2w	9NH	Tyrosine-protein kinase Lck	2.7.10.2	0.444
4nka	2K7	Fibroblast growth factor receptor 1	/	0.444
3qlf	PD5	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.440