sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3vhe | 42Q | Vascular endothelial growth factor receptor 2 | 2.7.10.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3vhe | 42Q | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 1.000 | |
| 3wze | BAX | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.603 | |
| 4asd | BAX | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.590 | |
| 3p7b | P7B | Mitogen-activated protein kinase 14 | / | 0.561 | |
| 5hid | B1E | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.555 | |
| 2e2b | 406 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.550 | |
| 1kv1 | BMU | Mitogen-activated protein kinase 14 | / | 0.546 | |
| 4hw7 | 64M | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.541 | |
| 3hv6 | R39 | Mitogen-activated protein kinase 14 | / | 0.531 | |
| 3ugc | 046 | Tyrosine-protein kinase JAK2 | / | 0.528 | |
| 2yis | YIS | Mitogen-activated protein kinase 14 | / | 0.525 | |
| 3p5k | P5K | Mitogen-activated protein kinase 14 | / | 0.525 | |
| 3p7c | P7C | Mitogen-activated protein kinase 14 | / | 0.523 | |
| 1wbv | LI3 | Mitogen-activated protein kinase 14 | / | 0.521 | |
| 3gcu | R48 | Mitogen-activated protein kinase 14 | / | 0.520 | |
| 3hv5 | R24 | Mitogen-activated protein kinase 14 | / | 0.520 | |
| 4r7i | STI | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.520 | |
| 3p78 | P78 | Mitogen-activated protein kinase 14 | / | 0.517 | |
| 1kv2 | B96 | Mitogen-activated protein kinase 14 | / | 0.516 | |
| 3p7a | P7A | Mitogen-activated protein kinase 14 | / | 0.513 | |
| 1wbn | L09 | Mitogen-activated protein kinase 14 | / | 0.512 | |
| 1wbs | LI2 | Mitogen-activated protein kinase 14 | / | 0.512 | |
| 2puu | G2G | Mitogen-activated protein kinase 14 | / | 0.510 | |
| 3d83 | GK6 | Mitogen-activated protein kinase 14 | / | 0.509 | |
| 3cs9 | NIL | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.507 | |
| 2hiw | 7MP | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.506 | |
| 3nnx | EDD | Mitogen-activated protein kinase 14 | / | 0.506 | |
| 3t54 | ATP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.506 | |
| 3gcv | SS6 | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.501 | |
| 3nnw | EDD | Mitogen-activated protein kinase 14 | / | 0.500 | |
| 1c6y | MK1 | Protease | / | 0.499 | |
| 2hzn | KIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.499 | |
| 3hv7 | 1AU | Mitogen-activated protein kinase 14 | / | 0.499 | |
| 3gi3 | B10 | Mitogen-activated protein kinase 14 | / | 0.497 | |
| 3o8u | BMU | Mitogen-activated protein kinase 14 | / | 0.497 | |
| 3p79 | P79 | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 2qhc | AB1 | Protease | / | 0.490 | |
| 1wbt | WBT | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 3uvr | 06F | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.485 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.483 | |
| 1bx6 | BA1 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.482 | |
| 3nnu | EDB | Mitogen-activated protein kinase 14 | / | 0.482 | |
| 4b1v | LAB | Actin, alpha skeletal muscle | / | 0.482 | |
| 2uw6 | GVO | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.481 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.480 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.478 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.477 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.476 | |
| 1w82 | L10 | Mitogen-activated protein kinase 14 | / | 0.476 | |
| 2yiw | YIW | Mitogen-activated protein kinase 14 | / | 0.476 | |
| 3v04 | V04 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.476 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.475 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.475 | |
| 3k3j | F4C | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.475 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.474 | |
| 4nzo | ANP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.474 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.473 | |
| 2hc0 | AB2 | Protease | / | 0.473 | |
| 3gvu | STI | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.473 | |
| 3oog | YTP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.473 | |
| 4u03 | GTP | Cyclic GMP-AMP synthase | / | 0.472 | |
| 2hz0 | GIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.471 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 1wbk | 568 | Pol protein | / | 0.470 | |
| 3qw2 | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.470 | |
| 4k4p | 3TL | Gag-Pol polyprotein | / | 0.470 | |
| 3npc | B96 | Mitogen-activated protein kinase 9 | 2.7.11.24 | 0.469 | |
| 4hla | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.469 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.468 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.467 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.467 | |
| 3liv | E16 | Protease | / | 0.467 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.466 | |
| 3lit | E15 | Protease | / | 0.466 | |
| 4l8m | F46 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 1k2b | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.465 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.465 | |
| 3v01 | 3V0 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.465 | |
| 1hpo | UNI | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 1vyz | N5B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.464 | |
| 2pym | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 3hv4 | L51 | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 4bdg | P3J | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.464 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 1yet | GDM | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 2pv7 | NAD | T-protein | 1.3.1.12 | 0.463 | |
| 3tku | M77 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.463 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 3bwj | ARX | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 4eon | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3dne | LL1 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
| 5dul | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.461 | |
| 3dy7 | 1CX | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.460 | |
| 3ec0 | GRL | Gag-Pol polyprotein | 3.4.23.47 | 0.460 | |
| 3o9a | K14 | Pol polyprotein | / | 0.460 | |
| 3t99 | ADP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.460 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.459 | |
| 1w5v | BE3 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.459 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 2i4x | KGQ | Protease | / | 0.459 | |
| 2oh0 | 2PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 2r64 | 740 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 3cqw | CQW | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.459 | |
| 3ekt | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3qxo | X65 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 3s43 | 478 | Protease | / | 0.459 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.459 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.459 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.459 | |
| 1ec0 | BED | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 1mrx | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.458 | |
| 3nu3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4eh9 | 0OQ | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 4j5j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 1cm8 | ANP | Mitogen-activated protein kinase 12 | / | 0.457 | |
| 1me8 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.457 | |
| 1mei | MOA | Inosine-5'-monophosphate dehydrogenase | / | 0.457 | |
| 1ody | LP1 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.457 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 3bxs | DRS | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3dnd | LL2 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 1k2c | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1pf9 | ADP | 60 kDa chaperonin | / | 0.456 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.456 | |
| 2b7z | MK1 | Gag-Pol polyprotein | / | 0.456 | |
| 2qi5 | MZ7 | Gag-Pol polyprotein | / | 0.456 | |
| 3kdd | JZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3nux | 3NV | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.456 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3upj | U03 | Gag-Pol polyprotein | / | 0.456 | |
| 4js9 | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.456 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.456 | |
| 2uy0 | HV1 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3nu5 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3r71 | X86 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.454 | |
| 2q64 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3rus | ADP | Chaperonin | / | 0.454 | |
| 3vfa | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 4dqc | 017 | Gag-Pol polyprotein | / | 0.454 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4heg | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 5ks7 | 2BA | Carnitine transport ATP-binding protein OpuCA | 3.6.3.32 | 0.454 | |
| 1b6p | PI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1meu | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1s9j | BBM | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.453 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 3dcr | KVS | Protease | / | 0.453 | |
| 4d4s | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.453 | |
| 4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 1b6m | PI6 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2bpv | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.452 | |
| 3rm7 | 19Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3s00 | Z60 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.452 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.452 | |
| 1d4y | TPV | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1qbs | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2f8g | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2r5q | 1UN | Gag-Pol polyprotein | / | 0.451 | |
| 2uvz | GVJ | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 3d1x | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3os3 | 3OS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.451 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.451 | |
| 9hvp | 0E9 | Gag-Pol polyprotein | / | 0.451 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.450 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.450 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.450 | |
| 4iwx | ADP | Ribosomal protein S6--L-glutamate ligase | / | 0.450 | |
| 4s26 | SAH | Phosphomethylpyrimidine synthase, chloroplastic | 4.1.99.17 | 0.450 | |
| 4wlv | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.450 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.450 | |
| 1c6x | 3IN | Protease | / | 0.449 | |
| 1hsh | MK1 | Gag-Pol polyprotein | / | 0.449 | |
| 1q8u | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.449 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2pyn | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2uw7 | GVP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 4an9 | 2P7 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.449 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.449 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 4q1x | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 6gsx | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.449 | |
| 1d4k | PI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1gx1 | CDP | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.448 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2qd8 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2uxz | HI1 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2vo0 | M03 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3agl | A03 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.448 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.448 | |
| 4ans | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.448 | |
| 4dqe | 017 | Gag-Pol polyprotein | / | 0.448 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.448 | |
| 1c6z | ROC | Protease | / | 0.447 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.447 | |
| 1kzk | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.447 | |
| 3orn | 3OR | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.447 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4an3 | 5Y0 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.447 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.447 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.447 | |
| 4njt | 017 | Protease | / | 0.447 | |
| 1a9m | U0E | Gag-Pol polyprotein | / | 0.446 | |
| 1hck | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1hiv | 1ZK | Gag-Pol polyprotein | / | 0.446 | |
| 1idb | 0DO | Gag-Pol polyprotein | / | 0.446 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.446 | |
| 3i6o | GR6 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.446 | |
| 4e5j | 581 | Polymerase acidic protein | / | 0.446 | |
| 4fk6 | 0UJ | Tyrosine-protein kinase JAK1 | / | 0.446 | |
| 4fsy | HK7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.446 | |
| 4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.446 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.446 | |
| 1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1hpx | KNI | Gag-Pol polyprotein | / | 0.445 | |
| 1msn | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1q3s | ADP | Thermosome subunit alpha | / | 0.445 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2qak | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 3q92 | XNB | Ketohexokinase | / | 0.445 | |
| 3rga | LSB | Epoxide hydrolase LasB | 5.5.1 | 0.445 | |
| 3s54 | 017 | Protease | / | 0.445 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.445 | |
| 5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.445 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.444 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.444 | |
| 3qih | FG7 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 4ehv | 0SJ | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4fkj | 11K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4jse | QJ2 | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1h48 | CDI | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.443 | |
| 1ke7 | LS3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 1sdu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2bb9 | AKC | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2q54 | MU1 | Protease | / | 0.443 | |
| 3nls | 016 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 3zo4 | QWI | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.443 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.443 | |
| 4l45 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.442 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.442 | |
| 1hnv | TBO | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1mer | DMQ | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1wbm | BLL | Pol protein | / | 0.442 | |
| 2qi4 | MZ6 | Gag-Pol polyprotein | / | 0.442 | |
| 2vo3 | M04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3el0 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.442 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.442 | |
| 3vvh | 4BM | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.442 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4dce | 0JF | ALK tyrosine kinase receptor | 2.7.10.1 | 0.442 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
| 4njs | G08 | Protease | / | 0.442 | |
| 5ani | ES4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3ndt | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4lj7 | MNT | Chaperone protein ClpB | / | 0.441 | |
| 1bdq | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1e8w | QUE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1nf7 | RVP | Inosine-5'-monophosphate dehydrogenase 2 | / | 0.440 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.440 | |
| 2cn8 | DBQ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 2j62 | GSZ | O-GlcNAcase NagJ | / | 0.440 | |
| 2j9m | PY8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2qci | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2qhy | MZ1 | Gag-Pol polyprotein | / | 0.440 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2yfx | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.440 | |
| 3bqr | 4RB | Death-associated protein kinase 3 | / | 0.440 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3pwr | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4fxf | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.440 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 |