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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3v8vSAMRibosomal RNA large subunit methyltransferase K/L2.1.1.173

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3v8vSAMRibosomal RNA large subunit methyltransferase K/L2.1.1.1731.000
3v97SAHRibosomal RNA large subunit methyltransferase K/L2.1.1.1730.631
3ldfSAHUncharacterized protein/0.494
2ytzSAHtRNA (guanine(26)-N(2))-dimethyltransferase/0.440