sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 1.000 | |
| 2qiq | CYV | Replicase polyprotein 1ab | / | 0.543 | |
| 2gz8 | F3F | Orf1a polyprotein | / | 0.525 | |
| 2op9 | WR1 | Orf1ab polyprotein | / | 0.514 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.511 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.461 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.455 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.455 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.452 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.450 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.447 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.445 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.444 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.444 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.443 | |
| 3mj5 | GRM | Replicase polyprotein 1a | 3.4.22 | 0.441 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.440 |