Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3v36 | NAP | Aldose reductase | 1.1.1.21 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
3v36 | NAP | Aldose reductase | 1.1.1.21 | 1.000 | |
2iq0 | NAP | Aldose reductase | 1.1.1.21 | 0.647 | |
1x96 | NAP | Aldose reductase | 1.1.1.21 | 0.645 | |
2acq | NAP | Aldose reductase | 1.1.1.21 | 0.644 | |
1z8a | NAP | Aldose reductase | 1.1.1.21 | 0.641 | |
1x98 | NAP | Aldose reductase | 1.1.1.21 | 0.632 | |
1ads | NAP | Aldose reductase | 1.1.1.21 | 0.613 | |
3q65 | NAP | Aldose reductase | 1.1.1.21 | 0.611 | |
2j8t | NAP | Aldose reductase | 1.1.1.21 | 0.610 | |
2pfh | NDP | Aldose reductase | 1.1.1.21 | 0.609 | |
1az2 | NAP | Aldose reductase | 1.1.1.21 | 0.608 | |
2acs | NAP | Aldose reductase | 1.1.1.21 | 0.605 | |
3q67 | NAP | Aldose reductase | 1.1.1.21 | 0.597 | |
1ah4 | NAP | Aldose reductase | 1.1.1.21 | 0.590 | |
2pev | NDP | Aldose reductase | 1.1.1.21 | 0.584 | |
2acu | NAP | Aldose reductase | 1.1.1.21 | 0.583 | |
2pf8 | NDP | Aldose reductase | 1.1.1.21 | 0.572 | |
3h7u | NAP | NADPH-dependent aldo-keto reductase, chloroplastic | / | 0.538 | |
3qkz | NAP | Aldose reductase-related protein 1 | 1.1.1.21 | 0.534 | |
3o3r | NAP | Aldose reductase-related protein 1 | 1.1.1.21 | 0.533 | |
4g5d | NDP | Prostaglandin F synthase | 1.1.1.188 | 0.514 | |
1k8c | NAP | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.500 | |
1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.489 | |
2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.489 | |
1c9w | NAP | Aldose reductase-related protein 2 | / | 0.488 | |
1r38 | NAP | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.484 | |
3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.479 | |
4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.478 | |
3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.477 | |
2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.474 | |
1ye6 | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.468 | |
4jtc | NAP | Voltage-gated potassium channel subunit beta-2 | / | 0.463 | |
1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
1zgd | NAP | Chalcone reductase | / | 0.453 | |
3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 |