sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3v35 | NTI | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 1.000 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.713 | |
| 3s3g | TLT | Aldose reductase | 1.1.1.21 | 0.701 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.664 | |
| 1ef3 | FID | Aldose reductase | 1.1.1.21 | 0.657 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.647 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.640 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.637 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.635 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.630 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.629 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.624 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.617 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.609 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.604 | |
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.593 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.587 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.583 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.581 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.575 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.574 | |
| 1ads | NAP | Aldose reductase | 1.1.1.21 | 0.565 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.558 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.556 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.555 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.554 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.551 | |
| 1az1 | ALR | Aldose reductase | 1.1.1.21 | 0.550 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.550 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.538 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.536 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.536 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.535 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.527 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
| 3cv7 | C2U | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.524 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.523 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.523 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.521 | |
| 1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
| 2ipw | 2CL | Aldose reductase | 1.1.1.21 | 0.520 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.519 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.518 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.518 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.517 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.517 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.516 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.515 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.510 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.510 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.509 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.508 | |
| 1lke | DOG | Bilin-binding protein | / | 0.507 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.506 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.506 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.505 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.505 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.505 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.503 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.503 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.501 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.500 | |
| 2j7c | IDE | Beta-glucosidase A | 3.2.1.21 | 0.500 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.500 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.498 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.497 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.496 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.495 | |
| 3h4g | FID | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.495 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.495 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.495 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.495 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.494 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.494 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.494 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.494 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.492 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.492 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.492 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.491 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.491 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.491 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.491 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.489 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.489 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.489 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.489 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.489 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.488 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.488 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.488 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.487 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.487 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.485 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.485 | |
| 1o1t | 2NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.484 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.484 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.484 | |
| 1rxj | BNI | Streptavidin | / | 0.483 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.483 | |
| 3c1o | NAP | Eugenol synthase | / | 0.483 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.482 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.482 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.482 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.482 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.482 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.482 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.481 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.481 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.481 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.481 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.481 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.481 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.479 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.479 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.479 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.479 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.479 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.479 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.478 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.478 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.478 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.478 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.478 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.477 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.477 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.477 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.477 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.477 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.476 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.476 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.476 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.476 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.475 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.475 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.475 | |
| 1e6z | NGO | Chitinase | / | 0.474 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.474 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.474 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.474 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.474 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.474 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.473 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.473 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2ejz | SAH | Diphthine synthase | / | 0.473 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 3u3o | 3QV | Sulfotransferase 1A1 | 2.8.2.1 | 0.473 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.473 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.473 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.472 | |
| 3zo7 | K6H | Muconolactone Delta-isomerase | / | 0.472 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.471 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.471 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.471 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.471 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.471 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.470 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.470 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.470 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.470 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.470 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.470 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.470 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.470 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.470 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.470 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.469 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.469 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.469 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.469 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.469 | |
| 4ixt | 1H1 | Halohydrin dehalogenase | / | 0.469 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.468 | |
| 1m2x | MCO | Metallo-beta-lactamase type 2 | / | 0.468 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.468 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 2hzq | STR | Apolipoprotein D | / | 0.468 | |
| 2qry | TPS | Thiamine-binding periplasmic protein | / | 0.468 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3klb | FMN | Uncharacterized protein | / | 0.468 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.467 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 5dsg | 0HK | Muscarinic acetylcholine receptor M4 | / | 0.467 | |
| 2bd0 | BIO | Sepiapterin reductase | / | 0.466 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.466 | |
| 2o4g | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.466 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.466 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.465 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.465 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.465 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.465 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.465 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.464 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.464 | |
| 1swg | BTN | Streptavidin | / | 0.464 | |
| 1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.464 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.464 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.464 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.464 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.464 | |
| 4a33 | PS8 | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4kmz | FOL | Folate receptor beta | / | 0.464 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1u08 | PLP | Methionine aminotransferase | / | 0.463 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.463 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 1xnz | FCD | Methionine aminopeptidase | / | 0.462 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.462 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.462 | |
| 3pzc | GAP | Amino acid--[acyl-carrier-protein] ligase 1 | 6.2.1.n2 | 0.462 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.462 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 4bvh | OCZ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.462 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.461 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 2r7n | ADP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | / | 0.461 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.461 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.461 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.461 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.461 | |
| 1a26 | CNA | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.460 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.460 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4j7g | TRH | PCZA361.3 | / | 0.460 | |
| 1fml | RTL | Retinol dehydratase | / | 0.459 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.459 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.459 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.459 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.459 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.459 | |
| 4mz7 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.459 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.458 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.458 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.458 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.458 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.458 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.458 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.458 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.458 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.458 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 4rxr | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.458 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.458 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.457 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.457 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.457 | |
| 2iej | S48 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.457 | |
| 4j7h | TRH | PCZA361.3 | / | 0.457 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.457 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.457 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.456 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.456 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.456 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 3cui | X4S | Exoglucanase/xylanase | 3.2.1.91 | 0.456 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.456 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.456 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.456 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3pn1 | IVH | DNA ligase | / | 0.456 | |
| 3voi | RCB | Glucanase | / | 0.456 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.456 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.456 | |
| 4yfy | 0FX | VioF | / | 0.456 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.455 | |
| 1lel | BH7 | Avidin | / | 0.455 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.455 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.455 | |
| 2ch2 | KY1 | Serine--pyruvate aminotransferase | / | 0.455 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.455 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.455 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.455 | |
| 4to2 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.455 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.454 | |
| 1m9h | NAD | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.454 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.454 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.454 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.454 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.454 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.453 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.453 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.453 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.453 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3p9t | TCL | Repressor | / | 0.453 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.453 | |
| 3vdc | IPT | Beta-galactosidase | 3.2.1.23 | 0.453 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.453 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.452 | |
| 1jf0 | CZH | Obelin | / | 0.452 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.452 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.452 | |
| 2f2h | XTG | Alpha-xylosidase | 3.2.1.177 | 0.452 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.452 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.452 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.452 | |
| 3fx4 | FX4 | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.452 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.452 | |
| 3ptq | NFG | Beta-glucosidase 12 | / | 0.452 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.451 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.451 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.451 | |
| 2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.451 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 2y1w | 849 | Histone-arginine methyltransferase CARM1 | / | 0.451 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.451 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.451 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4cb5 | 93G | Polymerase basic protein 2 | / | 0.451 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.451 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.451 | |
| 4zvn | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.451 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.451 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.450 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1lqa | NDP | Protein tas | / | 0.450 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.450 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.450 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.450 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.450 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3dla | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.450 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 3f90 | FMN | Flavodoxin | / | 0.450 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.450 | |
| 4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 1kf6 | HQO | Fumarate reductase iron-sulfur subunit | 1.3.5.1 | 0.449 | |
| 1kf6 | HQO | Fumarate reductase subunit C | / | 0.449 | |
| 1kf6 | HQO | Fumarate reductase subunit D | / | 0.449 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.449 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.449 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.449 | |
| 1z5u | CMP | Class B acid phosphatase | / | 0.449 | |
| 1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.449 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.449 | |
| 3i9k | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase | 3.2.2.6 | 0.449 | |
| 3jqc | JU2 | Pteridine reductase, putative | / | 0.449 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.449 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 1e2l | TMC | Thymidine kinase | / | 0.448 | |
| 1isj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.448 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.448 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.448 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.448 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.448 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.448 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.448 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 4l8v | NAP | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.448 | |
| 1jf2 | CZH | Obelin | / | 0.447 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.447 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.447 | |
| 1x2b | STX | Proline iminopeptidase | 3.4.11.5 | 0.447 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.447 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.447 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.447 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.447 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.446 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.446 | |
| 2j0s | ANP | Eukaryotic initiation factor 4A-III | 3.6.4.13 | 0.446 | |
| 2po3 | T4K | 4-dehydrase | / | 0.446 | |
| 2xeg | CI9 | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.446 | |
| 2xei | ARK | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.446 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.446 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.446 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.446 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.446 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4x3u | SVR | Chromobox protein homolog 7 | / | 0.446 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1e62 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 1el4 | CTZ | Obelin | / | 0.445 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.445 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 2y4s | BCD | Limit dextrinase | / | 0.445 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.445 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.445 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.445 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.445 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.445 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.445 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.445 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.445 | |
| 4to4 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.444 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.444 | |
| 1w88 | TDP | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.444 | |
| 1w88 | TDP | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.444 | |
| 2c6c | 24I | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.444 | |
| 2y1x | 845 | Histone-arginine methyltransferase CARM1 | / | 0.444 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.444 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3l67 | FMN | Xenobiotic reductase | / | 0.444 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.444 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.444 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.444 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4a1o | AMZ | Bifunctional purine biosynthesis protein PurH | 2.1.2.3 | 0.444 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4kn0 | MTX | Folate receptor beta | / | 0.444 | |
| 4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.444 | |
| 4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.444 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.443 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.443 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2gl0 | ADN | Uncharacterized protein | / | 0.443 | |
| 2xej | OKD | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.443 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.443 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.443 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4f79 | P53 | Putative phospho-beta-glucosidase | / | 0.443 | |
| 4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.443 | |
| 4jdc | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.443 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.443 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.443 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.442 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.442 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.442 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.442 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.442 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.442 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.442 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.442 | |
| 5dp2 | NAP | CurF | / | 0.442 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.442 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1hqt | NAP | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.441 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1uk1 | FRQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 2wgs | 1AZ | Glutamine synthetase | 6.3.1.2 | 0.441 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.441 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.441 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 3w5u | FAD | Ferredoxin | / | 0.441 | |
| 4a7y | NHF | Aldos-2-ulose dehydratase | / | 0.441 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.441 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.441 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.441 | |
| 1a80 | NDP | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.440 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 1k02 | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 1swn | BTN | Streptavidin | / | 0.440 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2g1a | 5HG | Class B acid phosphatase | 3.1.3.2 | 0.440 | |
| 2j7d | GI1 | Beta-glucosidase A | 3.2.1.21 | 0.440 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3eku | CY9 | Actin-5C | / | 0.440 | |
| 3gf4 | U5P | UDP-galactopyranose mutase | 5.4.99.9 | 0.440 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.440 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3sfx | JAN | Uncharacterized protein | / | 0.440 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.440 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.440 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.440 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.440 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.440 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.440 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4zas | TYD | CalS13 | / | 0.440 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.440 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.440 |