sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3u9y	09L	Tankyrase-2	2.4.2.30

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3u9y	09L	Tankyrase-2	2.4.2.30	1.000
4krs	1SX	Tankyrase-1	2.4.2.30	0.581
4tkg	09L	Tankyrase-2	2.4.2.30	0.569
4pnr	G18	Tankyrase-2	2.4.2.30	0.558
4bj9	UHB	Tankyrase-2	2.4.2.30	0.535
4msk	2C8	Tankyrase-1	2.4.2.30	0.522
4pnm	NU1	Tankyrase-2	2.4.2.30	0.505
4i9i	1DY	Tankyrase-1	2.4.2.30	0.494
4hyf	1AK	Tankyrase-2	2.4.2.30	0.485
4k4e	K4E	Tankyrase-1	2.4.2.30	0.479
4j3m	AJ8	Tankyrase-2	2.4.2.30	0.476
4bjc	RPB	Tankyrase-2	2.4.2.30	0.470
4li8	1XQ	Tankyrase-1	2.4.2.30	0.469
4li7	1XP	Tankyrase-1	2.4.2.30	0.465
4n4v	2GY	Tankyrase-1	2.4.2.30	0.461
4bjb	P34	Tankyrase-2	2.4.2.30	0.453
4k4f	K4F	Tankyrase-1	2.4.2.30	0.453