sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 1.000 | |
| 3o8h | O8H | HTH-type transcriptional regulator EthR | / | 0.664 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.657 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.639 | |
| 3sfi | 3SF | HTH-type transcriptional regulator EthR | / | 0.623 | |
| 3q0v | LL4 | HTH-type transcriptional regulator EthR | / | 0.611 | |
| 3g1l | RF2 | HTH-type transcriptional regulator EthR | / | 0.574 | |
| 3g1m | RF3 | HTH-type transcriptional regulator EthR | / | 0.552 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.535 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.498 | |
| 3g1o | RF1 | HTH-type transcriptional regulator EthR | / | 0.486 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.456 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.455 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.451 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.451 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.449 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1zdw | FLV | Prenyltransferase | / | 0.446 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.444 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.443 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.442 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.441 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.441 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.440 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 |