sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 1.000 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.617 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.613 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.612 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.604 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.589 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.583 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.580 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.579 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.576 | |
| 4gzl | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.575 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.570 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.569 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.568 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.567 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.566 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.554 | |
| 4nyi | GNP | GTPase HRas | / | 0.553 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.552 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.551 | |
| 4mit | GTP | Rho-related protein racC | / | 0.551 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.550 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.548 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.543 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.541 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.537 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.536 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.536 | |
| 3lbn | GNP | GTPase HRas | / | 0.536 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.534 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.533 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.532 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.531 | |
| 4nyj | GNP | GTPase HRas | / | 0.531 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.525 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.525 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.523 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.521 | |
| 3v4f | GNP | GTPase HRas | / | 0.519 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.519 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.517 | |
| 4dlw | GNP | GTPase HRas | / | 0.516 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.514 | |
| 3ddc | GNP | GTPase HRas | / | 0.513 | |
| 3i3s | GNP | GTPase HRas | / | 0.512 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.510 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.508 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.506 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.506 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.503 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.501 | |
| 5b2z | GNP | GTPase HRas | / | 0.501 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.499 | |
| 3oiu | GNP | GTPase HRas | / | 0.499 | |
| 3oiv | GNP | GTPase HRas | / | 0.498 | |
| 4dlt | GNP | GTPase HRas | / | 0.498 | |
| 4dxa | GSP | Ras-related protein Rap-1b | / | 0.498 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.496 | |
| 3rs5 | GNP | GTPase HRas | / | 0.496 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.495 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.494 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.493 | |
| 3rs7 | GNP | GTPase HRas | / | 0.490 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.490 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.487 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.486 | |
| 2c5l | GTP | GTPase HRas | / | 0.482 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.482 | |
| 4dso | GSP | GTPase KRas | / | 0.481 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.478 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.477 | |
| 1lfd | GNP | GTPase HRas | / | 0.476 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.474 | |
| 3kud | GDP | GTPase HRas | / | 0.473 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.472 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.471 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.470 | |
| 3rsl | GNP | GTPase HRas | / | 0.469 | |
| 3lbh | GNP | GTPase HRas | / | 0.466 | |
| 3rs0 | GNP | GTPase HRas | / | 0.464 | |
| 3l8y | GNP | GTPase HRas | / | 0.461 | |
| 4dsn | GCP | GTPase KRas | / | 0.461 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.458 | |
| 4dlz | GNP | GTPase HRas | / | 0.458 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.455 | |
| 4g0n | GNP | GTPase HRas | / | 0.454 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.453 | |
| 3lbi | GNP | GTPase HRas | / | 0.451 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.450 | |
| 2rge | GNP | GTPase HRas | / | 0.449 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.448 | |
| 3rs4 | GNP | GTPase HRas | / | 0.447 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.446 | |
| 5dif | GNP | GTP-binding nuclear protein Ran | / | 0.443 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 2rgb | GNP | GTPase HRas | / | 0.442 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.442 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.442 | |
| 2cl6 | CAG | GTPase HRas | / | 0.441 | |
| 3k8y | GNP | GTPase HRas | / | 0.440 |