sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3tba | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3tba | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 1.000 | |
| 2cvw | GDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.525 | |
| 2cvu | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.513 | |
| 3o0o | GDP | Vitamin B12-dependent ribonucleotide reductase | / | 0.478 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.467 | |
| 4jzy | FAD | Cryptochrome-1 | / | 0.458 | |
| 3s8c | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.457 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.455 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.450 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.450 | |
| 1xjk | ADP | Vitamin B12-dependent ribonucleotide reductase | / | 0.448 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.447 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.445 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 5dp2 | NAP | CurF | / | 0.443 | |
| 3k8t | 2A5 | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.441 |