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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3tb9CDPRibonucleoside-diphosphate reductase large chain 11.17.4.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3tb9CDPRibonucleoside-diphosphate reductase large chain 11.17.4.11.000
3k8t2A5Ribonucleoside-diphosphate reductase large chain 11.17.4.10.712
2eudGCQRibonucleoside-diphosphate reductase large chain 11.17.4.10.667
3s8cCDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.622
2cvwGDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.617
2cvuCDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.591
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.586
3tbaADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.539
4k6fNAPPutative Acetoacetyl-CoA reductase/0.531
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.529
3o0oGDPVitamin B12-dependent ribonucleotide reductase/0.524
5cnsCDPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.516
1ra8FOLDihydrofolate reductase1.5.1.30.513
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.510
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.509
1rd7FOLDihydrofolate reductase1.5.1.30.508
1hfqMOTDihydrofolate reductase1.5.1.30.506
1ra3NAPDihydrofolate reductase1.5.1.30.504
1rx8NAPDihydrofolate reductase1.5.1.30.504
4dptAGSMevalonate diphosphate decarboxylase/0.504
3atzFMNProstaglandin F2a synthase/0.503
3fp0FP015-O-acetyltransferase/0.502
1ra3MTXDihydrofolate reductase1.5.1.30.501
1nzdUPGDNA beta-glucosyltransferase/0.500
1o9bNAIQuinate/shikimate dehydrogenase/0.499
1w6hTITPlasmepsin-23.4.23.390.499
1xjkADPVitamin B12-dependent ribonucleotide reductase/0.499
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.499
3eldSFGMethyltransferase/0.498
1pjcNADAlanine dehydrogenase/0.496
1dyiFOLDihydrofolate reductase1.5.1.30.494
4dbzNDPPutative ketoacyl reductase1.3.10.494
4j491J1Uncharacterized protein/0.493
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.491
1wntNAPL-xylulose reductase1.1.1.100.491
4u0mGTPCyclic GMP-AMP synthase/0.489
1xjnCDPVitamin B12-dependent ribonucleotide reductase/0.488
2fy4COACholine O-acetyltransferase2.3.1.60.488
1pdhFASp-hydroxybenzoate hydroxylase/0.487
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.487
1drhNAPDihydrofolate reductase1.5.1.30.486
1vi2NADQuinate/shikimate dehydrogenase/0.486
2a9y26AAdenosine kinase2.7.1.200.486
3s1dZIRCytokinin dehydrogenase 11.5.99.120.486
1h74ADPHomoserine kinase2.7.1.390.485
3t4eNADQuinate/shikimate dehydrogenase/0.485
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.484
1ddsMTXDihydrofolate reductase1.5.1.30.484
4x5hFOLDihydrofolate reductase1.5.1.30.484
1dyjDDFDihydrofolate reductase1.5.1.30.483
1towCRZFatty acid-binding protein, adipocyte/0.482
4a4zANPAntiviral helicase SKI23.6.4.130.482
4ejmNAPPutative zinc-binding dehydrogenase/0.482
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.482
5hi6MTXDihydrofolate reductase/0.482
1bil0IURenin3.4.23.150.481
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.481
1rx1NAPDihydrofolate reductase1.5.1.30.481
2dsgSAHDiphthine synthase/0.481
2j4kU5PUridylate kinase2.7.4.220.481
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.481
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.480
3lsiFADPyranose 2-oxidase/0.480
1nzfUPGDNA beta-glucosyltransferase/0.479
1re7FOLDihydrofolate reductase1.5.1.30.478
1xe65FPPlasmepsin-23.4.23.390.478
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.478
2gtbAZPOrf1ab polyprotein/0.478
2rqfJH3Hemolymph juvenile hormone binding protein/0.478
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.478
3gviADPMalate dehydrogenase/0.478
1b2lNDCAlcohol dehydrogenase1.1.1.10.477
1udaUFGUDP-glucose 4-epimerase5.1.3.20.477
1xjmTTPVitamin B12-dependent ribonucleotide reductase/0.477
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.477
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.477
4l4eCAMCamphor 5-monooxygenase1.14.15.10.477
1ddrMTXDihydrofolate reductase1.5.1.30.476
1zgi382Prothrombin3.4.21.50.476
3bv2P38Mitogen-activated protein kinase 14/0.476
3pw8ACO1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.476
1dhiMTXDihydrofolate reductase1.5.1.30.475
1o76CAMCamphor 5-monooxygenase1.14.15.10.475
1vyrFMNPentaerythritol tetranitrate reductase/0.475
2y4gTIRTamL/0.475
3iqgASN_TRP_ASN_ILECysteine synthase2.5.1.470.475
4k6mSAHGenome polyprotein/0.475
4l4fCAMCamphor 5-monooxygenase1.14.15.10.475
1u71MXADihydrofolate reductase1.5.1.30.474
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.474
3uf6CODLmo1369 protein/0.474
4i0j842Beta-secretase 13.4.23.460.474
4i1iNADMalate dehydrogenase/0.474
4m83ERYOleandomycin glycosyltransferase2.4.10.474
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.474
1f20FADNitric oxide synthase, brain1.14.13.390.473
1zwlFMNNAD(P)H dehydrogenase (quinone)1.6.5.20.473
2a7r5GPGMP reductase 2/0.473
2gjlFMNNitronate monooxygenase1.13.12.160.473
2pb6SAHDiphthine synthase/0.473
2q46NAPUncharacterized protein At5g02240/0.473
3d84NDPDihydrofolate reductase1.5.1.30.473
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.473
4kgnSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.473
4m6jNDPDihydrofolate reductase1.5.1.30.473
1mewXMPInosine-5'-monophosphate dehydrogenase/0.472
2oapANPType II secretion system protein (GspE-2)/0.472
4dfrMTXDihydrofolate reductase1.5.1.30.472
4ke11R6Beta-secretase 13.4.23.460.472
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.471
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.471
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.471
1h73ANPHomoserine kinase2.7.1.390.471
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.471
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.471
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.471
2emuSAHDiphthine synthase/0.471
2hutSAHDiphthine synthase/0.471
2iyfERYOleandomycin glycosyltransferase2.4.10.471
2wpxACOOrf14/0.471
3gvhNADMalate dehydrogenase/0.471
3h06VBPGlutamate receptor 2/0.471
3i0pNADMalate dehydrogenase, putative/0.471
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.471
3oqfS51Renin3.4.23.150.471
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.471
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.470
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.470
2a1oCAMCamphor 5-monooxygenase1.14.15.10.470
2zbaZBATrichothecene 3-O-acetyltransferase/0.470
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.470
3d3wNAPL-xylulose reductase1.1.1.100.470
3hk1B64Fatty acid-binding protein, adipocyte/0.470
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.470
4k28NADShikimate dehydrogenase family protein/0.470
4q0kGA3Phytohormone-binding protein/0.470
1d0vRBZNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.469
1xddAAYIntegrin alpha-L/0.469
2hu2NADC-terminal binding protein 1/0.469
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.469
2rkvZBATrichothecene 3-O-acetyltransferase/0.469
4i6gFADCryptochrome-2/0.469
4q72FADBifunctional protein PutA/0.469
4zj8SUVOrexin receptor type 1/0.469
1guyNADMalate dehydrogenase/0.468
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.468
2cftPLPPyridoxal phosphate phosphatase/0.468
2f3fAXFBeta-secretase 13.4.23.460.468
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.468
3kjm245Cytokinin dehydrogenase 11.5.99.120.468
3tozNADShikimate dehydrogenase (NADP(+))/0.468
4dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.468
4p9dTMPDeoxycytidylate deaminase/0.468
4z0g5GPInosine-5'-monophosphate dehydrogenase/0.468
1cs4FOKAdenylate cyclase type 2/0.467
1cs4FOKAdenylate cyclase type 5/0.467
2b8tTHMThymidine kinase/0.467
2o4cNADErythronate-4-phosphate dehydrogenase/0.467
2qenADPWalker-Type ATPase/0.467
3b2sB2STrichothecene 3-O-acetyltransferase/0.467
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3f03FMNPentaerythritol tetranitrate reductase/0.467
4jwfSAHtRNA (guanine(9)-N1)-methyltransferase/0.467
4kbyC2EStimulator of interferon genes protein/0.467
5jjsSAHGenome polyprotein/0.467
1diuBDMDihydrofolate reductase1.5.1.30.466
1dz8CAMCamphor 5-monooxygenase1.14.15.10.466
1tl7FOKAdenylate cyclase type 2/0.466
1tl7FOKAdenylate cyclase type 5/0.466
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.466
2a1mCAMCamphor 5-monooxygenase1.14.15.10.466
2ab8MTPAdenosine kinase2.7.1.200.466
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.466
2e8rSAHDiphthine synthase/0.466
2g1n1IGRenin3.4.23.150.466
3mdmFJZCholesterol 24-hydroxylase/0.466
3tqaNDPDihydrofolate reductase/0.466
3wrhCAMCamphor 5-monooxygenase1.14.15.10.466
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.466
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.466
1cjtFOKAdenylate cyclase type 2/0.465
1cjtFOKAdenylate cyclase type 5/0.465
1dyhDZFDihydrofolate reductase1.5.1.30.465
1mjaCOAHistone acetyltransferase ESA1/0.465
1t85CAMCamphor 5-monooxygenase1.14.15.10.465
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.465
2j08FADDeoxyribodipyrimidine photo-lyase4.1.99.30.465
2p6lSAHDiphthine synthase/0.465
3f63GTXGlutathione transferase GST1-4/0.465
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.465
3p74FMNPentaerythritol tetranitrate reductase/0.465
3vydVYDRenin3.4.23.150.465
4dh60KNBeta-secretase 13.4.23.460.465
4e2dFMNDehydrogenase/0.465
4kgkGTPUncharacterized protein/0.465
5d3qGDPDynamin-13.6.5.50.465
5fwnNAPPutative dehydrogenase/0.465
1ezvUQ6Cytochrome b/0.464
1kp2ATPArgininosuccinate synthase6.3.4.50.464
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.464
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.464
2briANPUridylate kinase2.7.4.220.464
2e4nSAHDiphthine synthase/0.464
2ft9CHDFatty acid-binding protein 2, liver/0.464
2qbmCAMCamphor 5-monooxygenase1.14.15.10.464
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.464
3qlsNDPDihydrofolate reductase1.5.1.30.464
3r9uFADThioredoxin reductase/0.464
4bfxZVXPantothenate kinase2.7.1.330.464
4f650S9Fibroblast growth factor receptor 1/0.464
4g95OAGDihydrofolate reductase1.5.1.30.464
4kl9NDPDihydrofolate reductase1.5.1.30.464
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.464
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.463
1culFOKAdenylate cyclase type 2/0.463
1culFOKAdenylate cyclase type 5/0.463
1omoNADAlanine dehydrogenase/0.463
1pq944BOxysterols receptor LXR-beta/0.463
1pvgANPDNA topoisomerase 25.99.1.30.463
1u2yGOXPancreatic alpha-amylase/0.463
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.463
2a94AP0L-lactate dehydrogenase1.1.1.270.463
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
2ejvNADL-threonine 3-dehydrogenase/0.463
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
2rlcCHDCholoylglycine hydrolase3.5.1.240.463
2vwqNAPGlucose 1-dehydrogenase/0.463
3ctyFADProbable thioredoxin reductase/0.463
3fr5I4AFatty acid-binding protein, adipocyte/0.463
3fwiCAMCamphor 5-monooxygenase1.14.15.10.463
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.463
3w2jQRODihydroorotate dehydrogenase (fumarate)1.3.98.10.463
4q71FADBifunctional protein PutA/0.463
1gpeFADGlucose oxidase1.1.3.40.462
1l4lNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.462
1l4mNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.462
1pd9CO4Dihydrofolate reductase1.5.1.30.462
1touB1VFatty acid-binding protein, adipocyte/0.462
1ur5NADMalate dehydrogenase/0.462
2ghlLIBMitogen-activated protein kinase 14/0.462
2he5NDPAldo-keto reductase family 1 member C211.1.10.462
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.462
2nnqT4BFatty acid-binding protein, adipocyte/0.462
3b70NAPEnoyl reductase LovC10.462
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.462
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.462
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.462
4qxq1YEStimulator of interferon genes protein/0.462
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.462
1b8vNADMalate dehydrogenase/0.461
1g1aNADdTDP-glucose 4,6-dehydratase/0.461
1svwGTPProbable GTP-binding protein EngB/0.461
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.461
2drcMTXDihydrofolate reductase1.5.1.30.461
2g1r3IGRenin3.4.23.150.461
2omeNADC-terminal-binding protein 2/0.461
2rhrEMOPutative ketoacyl reductase1.3.10.461
3ajrNADNDP-sugar epimerase/0.461
3gqvNAPEnoyl reductase LovC10.461
3h3jNADL-lactate dehydrogenase 11.1.1.270.461
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3lnc5GPGuanylate kinase/0.461
3qlrNDPDihydrofolate reductase1.5.1.30.461
4rww2BALmo2692 protein/0.461
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.461
4xj43ATCyclic GMP-AMP synthase/0.461
1kvkATPMevalonate kinase2.7.1.360.460
1l4fNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.460
1tehNADAlcohol dehydrogenase class-31.1.1.10.460
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2d0kFOLDihydrofolate reductase1.5.1.30.460
2hfuMEVMevalonate kinase/0.460
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.460
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.460
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.460
3q9bB3NAcetylpolyamine amidohydrolase/0.460
1m78NDPDihydrofolate reductase1.5.1.30.459
1n3rGTPGTP cyclohydrolase 13.5.4.160.459
1u4oNDDL-lactate dehydrogenase1.1.1.270.459
1xe55FEPlasmepsin-23.4.23.390.459
2rh9IGPTryptophan synthase alpha chain/0.459
2v16C47Renin3.4.23.150.459
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.459
3och2MXDihydrofolate reductase1.5.1.30.459
4du82P0Mevalonate diphosphate decarboxylase/0.459
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.459
4ei7GDPPlasmid replication protein RepX/0.459
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.459
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.459
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.459
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.459
4lxb7R9Prothrombin3.4.21.50.459
4tuvCPZCytochrome P450 1191.140.459
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1kfbIGPTryptophan synthase alpha chain/0.458
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2af3COAPhosphate acetyltransferase2.3.1.80.458
2cv2GSUGlutamate--tRNA ligase6.1.1.170.458
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.458
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.458
3aebFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.458
3mjeNDPAmphB/0.458
3oafOAGDihydrofolate reductase1.5.1.30.458
3vswR31Renin3.4.23.150.458
4b4vL34Bifunctional protein FolD/0.458
4ctjSAMGenome polyprotein/0.458
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.458
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.458
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.458
4i02CMPcAMP-activated global transcriptional regulator CRP/0.458
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.458
1dr3TAPDihydrofolate reductase1.5.1.30.457
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.457
2bjfDXCCholoylglycine hydrolase3.5.1.240.457
2ed3SAHDiphthine synthase/0.457
2egsSAHDiphthine synthase/0.457
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.457
3a0tADPSensor histidine kinase/0.457
3l63CAMCamphor 5-monooxygenase1.14.15.10.457
3lqfNADGalactitol dehydrogenase/0.457
3vyfVYFRenin3.4.23.150.457
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.457
3zksWZVBeta-secretase 23.4.23.450.457
4f9gC2EStimulator of interferon genes protein/0.457
4i8vBHFCytochrome P450 1A11.14.14.10.457
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.457
4nbwNADShort-chain dehydrogenase/reductase SDR/0.457
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.457
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.457
1dgmADNAdenosine kinase2.7.1.200.456
1p31EPUUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.456
2c29NAPDihydroflavonol 4-reductase/0.456
2e7rSAHDiphthine synthase/0.456
2ge3ACOProbable acetyltransferase/0.456
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
2pxaSAHGenome polyprotein2.7.7.480.456
2rkgAB1Pol protein/0.456
2v34CTN4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.456
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.456
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.456
3fwjCAMCamphor 5-monooxygenase1.14.15.10.456
3n0hTOPDihydrofolate reductase1.5.1.30.456
3phiNDPShikimate dehydrogenase (NADP(+))/0.456
3qt62P0Mevalonate diphosphate decarboxylase/0.456
3rasNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.456
3triNAPPyrroline-5-carboxylate reductase/0.456
3zcsCAWGlycogen phosphorylase, muscle form2.4.1.10.456
4b99R4LMitogen-activated protein kinase 72.7.11.240.456
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.456
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.456
4loi1YCStimulator of interferon genes protein/0.456
4lol1YEStimulator of interferon genes protein/0.456
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.456
4udrFAD5-(hydroxymethyl)furfural oxidase/0.456
4yp7NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.456
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.455
1esvLARActin, alpha skeletal muscle/0.455
1u3dFADCryptochrome-1/0.455
1xjeGDPVitamin B12-dependent ribonucleotide reductase/0.455
2c3cNAP2-oxopropyl-CoM reductase, carboxylating1.8.1.50.455
2givACOHistone acetyltransferase KAT8/0.455
2x0rNADMalate dehydrogenase/0.455
2y0mACOHistone acetyltransferase KAT8/0.455
3cvuFADRE11660p/0.455
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.455
3n4l842Beta-secretase 13.4.23.460.455
3otwCOAPhosphopantetheine adenylyltransferase/0.455
3q33ACOHistone acetyltransferase RTT1092.3.1.480.455
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.455
3t2vKKJPeptidoglycan recognition protein 1/0.455
3wmxNADNAD dependent epimerase/dehydratase/0.455
4h1e10JBeta-secretase 13.4.23.460.455
4ki0ANPMaltose/maltodextrin import ATP-binding protein MalK/0.455
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.455
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.455
4q73FADBifunctional protein PutA/0.455
4xboSAHtRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ2.1.1.2000.455
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.455
1a72PADAlcohol dehydrogenase E chain1.1.1.10.454
1cjuFOKAdenylate cyclase type 2/0.454
1cjuFOKAdenylate cyclase type 5/0.454
1il0NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.454
1mj9COAHistone acetyltransferase ESA1/0.454
1tdrMTXDihydrofolate reductase1.5.1.30.454
1v453DGPurine nucleoside phosphorylase2.4.2.10.454
2dftADPShikimate kinase2.7.1.710.454
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.454
2ek7SAHDiphthine synthase/0.454
2znpK55Peroxisome proliferator-activated receptor delta/0.454
3i6qNDPPutative leucoanthocyanidin reductase 1/0.454
3maaFKPAdenylate cyclase type 2/0.454
3maaFKPAdenylate cyclase type 5/0.454
3mpt1GKMitogen-activated protein kinase 14/0.454
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.454
3p62FMNPentaerythritol tetranitrate reductase/0.454
3p8z36AGenome polyprotein2.1.1.560.454
3tog079Gag-Pol polyprotein2.7.7.490.454
3uylTYDProbable NDP-rhamnosyltransferase/0.454
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
4egbNADdTDP-glucose 4,6-dehydratase/0.454
4gk3L87Ephrin type-A receptor 32.7.10.10.454
4qxr1YEStimulator of interferon genes protein/0.454
4tvbNADHomospermidine synthase2.5.1.440.454
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.453
1cscCMCCitrate synthase, mitochondrial2.3.3.10.453
1dhfFOLDihydrofolate reductase1.5.1.30.453
1f0yCAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.453
1owe675Urokinase-type plasminogen activator3.4.21.730.453
1t2cNAIL-lactate dehydrogenase1.1.1.270.453
1t88CAMCamphor 5-monooxygenase1.14.15.10.453
1uxjNADMalate dehydrogenase/0.453
1xelUPGUDP-glucose 4-epimerase5.1.3.20.453
2ejjSAHDiphthine synthase/0.453
2fj1CTCTetracycline repressor protein class D/0.453
2jh5895Prothrombin3.4.21.50.453
2p6iSAHDiphthine synthase/0.453
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.453
3b20NADGlyceraldehyde-3-phosphate dehydrogenase/0.453
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.453
3lsmSFDPyranose 2-oxidase/0.453
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.453
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.453
3orfNADDihydropteridine reductase1.5.1.340.453
3own3OXRenin3.4.23.150.453
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.453
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.453
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.453
4xr9NADCalS8/0.453
1l4gNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.452
1meiXMPInosine-5'-monophosphate dehydrogenase/0.452
1rfuADPPyridoxal kinase2.7.1.350.452
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.452
1t87CAMCamphor 5-monooxygenase1.14.15.10.452
1yjqNAP2-dehydropantoate 2-reductase1.1.1.1690.452
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.452
2b53D23Cyclin-dependent kinase 22.7.11.220.452
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.452
2j08IRFDeoxyribodipyrimidine photo-lyase4.1.99.30.452
2npxFADNADH peroxidase1.11.1.10.452
2ou2ACOHistone acetyltransferase KAT5/0.452
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.452
2xpuTDCTetracycline repressor protein class D/0.452
2y3sTIRTamL/0.452
2z6uSAHModification methylase HhaI2.1.1.370.452
3b9lAZZSerum albumin/0.452
3cvyFADRE11660p/0.452
3g6zA7TRenin3.4.23.150.452
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.452
3oibFDAPutative acyl-CoA dehydrogenase/0.452
3vsxR32Renin3.4.23.150.452
4dpy2P0Mevalonate diphosphate decarboxylase/0.452
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4lrzADPPEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.452
4x5jFOLDihydrofolate reductase1.5.1.30.452
1bl6SB6Mitogen-activated protein kinase 14/0.451
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.451
1ia1NDPDihydrofolate reductase1.5.1.30.451
1kevNDPNADP-dependent isopropanol dehydrogenase1.1.1.800.451
1mjbACOHistone acetyltransferase ESA1/0.451
1toiHCIAspartate aminotransferase2.6.1.10.451
1z7yAA5Cysteine synthase 12.5.1.470.451
2bn4NAPNADPH--cytochrome P450 reductase/0.451
2c27ACOMycothiol acetyltransferase2.3.1.1890.451
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.451
2ep7NADGlyceraldehyde-3-phosphate dehydrogenase/0.451
2ozuACOHistone acetyltransferase KAT6A/0.451
2po7CHDFerrochelatase, mitochondrial4.99.1.10.451
2rcyNAPPyrroline-5-carboxylate reductase/0.451
3e39FMNNitroreductase/0.451
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.451
3lm9ADPPutative fructokinase2.7.1.40.451
3wrjCAMCamphor 5-monooxygenase1.14.15.10.451
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4bj9UHBTankyrase-22.4.2.300.451
5bsfNADPyrroline-5-carboxylate reductase/0.451
1dhjMTXDihydrofolate reductase1.5.1.30.450
1dhrNADDihydropteridine reductase1.5.1.340.450
1dz6CAMCamphor 5-monooxygenase1.14.15.10.450
1hkuNADC-terminal-binding protein 11.1.10.450
1nooCAHCamphor 5-monooxygenase1.14.15.10.450
1npdNADQuinate/shikimate dehydrogenase/0.450
1rm4NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.450
1w5tADPORC1-type DNA replication protein 2/0.450
2b4rNADGlyceraldehyde-3-phosphate dehydrogenase/0.450
2ed5SAHDiphthine synthase/0.450
2emrSAHDiphthine synthase/0.450
2j09FMNDeoxyribodipyrimidine photo-lyase4.1.99.30.450
2v58LZJBiotin carboxylase6.3.4.140.450
2vkmBSDBeta-secretase 13.4.23.460.450
2zgb21UProthrombin3.4.21.50.450
3c1kT15Prothrombin3.4.21.50.450
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3f1kNAPUncharacterized oxidoreductase YciK10.450
3fsjD7KBenzoylformate decarboxylase4.1.1.70.450
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.450
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.450
3own3OWRenin3.4.23.150.450
3p0jTYEPutative tyrosyl-tRNA synthetase/0.450
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.1460.450
4cnfMTASpoU rRNA methylase/0.450
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.450
4fuj1U9Urokinase-type plasminogen activator3.4.21.730.450
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.450
4hlk431Tankyrase-22.4.2.300.450
4i1nFOLDihydrofolate reductase1.5.1.30.450
4i4b1CV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.450
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.450
4yntFDAGlucose oxidase, putative/0.450
6cp4CAMCamphor 5-monooxygenase1.14.15.10.450
1h50FMNPentaerythritol tetranitrate reductase/0.449
1j3kNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
1rszDIHPurine nucleoside phosphorylase2.4.2.10.449
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.449
1tj0FADBifunctional protein PutA1.5.5.20.449
1uxkNADMalate dehydrogenase/0.449
1vja7INUrokinase-type plasminogen activator3.4.21.730.449
2djxFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.449
2wo7ASVIsopenicillin N synthase1.21.3.10.449
2y3rTRKTamL/0.449
2ylxFADPhenylacetone monooxygenase1.14.13.920.449
2zhq27UProthrombin3.4.21.50.449
2znk31UProthrombin3.4.21.50.449
2zshGA3Gibberellin receptor GID1A30.449
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.449
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.449
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.449
3u8l09QAcetylcholine-binding protein/0.449
3u9eCOALmo1369 protein/0.449
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.449
4bfvZVVPantothenate kinase2.7.1.330.449
4lcjNADC-terminal-binding protein 2/0.449
4lxm1YUBeta-secretase 13.4.23.460.449
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.449
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.449
4qysPLRTryptophan synthase beta chain 24.2.1.200.449
1ai9NDPDihydrofolate reductase1.5.1.30.448
1cnfFADNitrate reductase [NADH]1.7.1.10.448
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.448
1s3uTQDDihydrofolate reductase1.5.1.30.448
1wzeNADMalate dehydrogenase/0.448
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2eklNADD-3-phosphoglycerate dehydrogenase/0.448
2huqSAHDiphthine synthase/0.448
2i7nACOPantothenate kinase 12.7.1.330.448
2idkC2FGlycine N-methyltransferase2.1.1.200.448
2os1BB2Peptide deformylase/0.448
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.448
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.448
3a3gDLZLumazine protein/0.448
3d4pNADL-lactate dehydrogenase 11.1.1.270.448
3ft5MO8Heat shock protein HSP 90-alpha/0.448
3ik6HCZGlutamate receptor 2/0.448
3ksdNADGlyceraldehyde-3-phosphate dehydrogenase 1/0.448
3l0lHC3Nuclear receptor ROR-gamma/0.448
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.448
4fncHMUG/T mismatch-specific thymine DNA glycosylase3.2.2.290.448
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.448
4pzkSAHPutative tRNA (cytidine(34)-2'-O)-methyltransferase/0.448
4qxp1YEStimulator of interferon genes protein/0.448
4ztvTA7Anthranilate phosphoribosyltransferase/0.448
5a1tNAIL-lactate dehydrogenase/0.448
5a9sNAPPutative dehydrogenase/0.448
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.448
1adfTADAlcohol dehydrogenase E chain1.1.1.10.447
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.447
1cjvFOKAdenylate cyclase type 2/0.447
1cjvFOKAdenylate cyclase type 5/0.447
1h51FMNPentaerythritol tetranitrate reductase/0.447
1rneC60Renin3.4.23.150.447
1tqf32PBeta-secretase 13.4.23.460.447
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.447
2b51UTPRNA editing complex protein MP57/0.447
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.447
2ejzSAHDiphthine synthase/0.447
2npnSAMPutative cobalamin synthesis related protein/0.447
2rc4ACOHistone acetyltransferase KAT6A/0.447
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.447
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
2z4sADPChromosomal replication initiator protein DnaA/0.447
3ibqATPPyridoxal kinase/0.447
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
3k5fAYHBeta-secretase 13.4.23.460.447
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.447
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.447
3mvm39PMitogen-activated protein kinase 14/0.447
3phjDHKShikimate dehydrogenase (NADP(+))/0.447
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.447
3to6LYS_CMCHistone acetyltransferase ESA1/0.447
3wb2YGPUncharacterized protein MJ0488/0.447
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4eu5COASuccinyl-CoA:acetate CoA-transferase/0.447
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.447
4f5yC2EStimulator of interferon genes protein/0.447
1jscTPPAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.446
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.446
1mvtDTMDihydrofolate reductase1.5.1.30.446
1rx7FOLDihydrofolate reductase1.5.1.30.446
1rz0FADPhenol 2-hydroxylase component B/0.446
1v59NADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.446
1yrdCAMCamphor 5-monooxygenase1.14.15.10.446
2ahvCOAAcetate CoA-transferase YdiF2.8.3.80.446
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2eniSAHDiphthine synthase/0.446
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.446
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.446
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.446
3b6zCO7Enoyl reductase LovC10.446
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3p67FMNPentaerythritol tetranitrate reductase/0.446
3wrmCAMCamphor 5-monooxygenase1.14.15.10.446
4a99FADTetX family tetracycline inactivation enzyme/0.446
4c72TLG3-oxoacyl-ACP synthase/0.446
4fizCUE17beta-hydroxysteroid dehydrogenase/0.446
4friDWABeta-secretase 13.4.23.460.446
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.446
4jin1L7RIO-type serine/threonine-protein kinase Rio12.7.11.10.446
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.446
4y35F90Endothiapepsin3.4.23.220.446
1bk0ACVIsopenicillin N synthase1.21.3.10.445
1bmdNADMalate dehydrogenase/0.445
1bzfTMQDihydrofolate reductase1.5.1.30.445
1dj2GDPAdenylosuccinate synthetase, chloroplastic/0.445
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
1jkx138Phosphoribosylglycinamide formyltransferase/0.445
1krhFADBenzoate 1,2-dioxygenase electron transfer component1.18.1.30.445
1mbtFADUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.445
1nboNADGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.445
1o6zNADMalate dehydrogenase/0.445
1pqc444Oxysterols receptor LXR-beta/0.445
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.445
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.445
2a5kAZPReplicase polyprotein 1ab3.4.220.445
2dxxSAHDiphthine synthase/0.445
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.445
2oo5TXDNAD(P) transhydrogenase subunit alpha part 11.6.1.20.445
2qfoA51Heat shock protein HSP 90-alpha/0.445
2vj7VG6Beta-secretase 13.4.23.460.445
2w9hTOPDihydrofolate reductase1.5.1.30.445
3nk7SAM23S rRNA (adenosine(1067)-2'-O)-methyltransferase/0.445
3nr4PYVAbscisic acid receptor PYL2/0.445
3rfxNADUronate dehydrogenase/0.445
3tkyN7I(Iso)eugenol O-methyltransferase2.1.1.1460.445
3zhbNAPPutative dehydrogenase/0.445
4aa4QC0Mitogen-activated protein kinase 14/0.445
4g6gFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.445
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.445
4mppTZDBenzoylformate decarboxylase4.1.1.70.445
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.445
4opgFDAConserved Archaeal protein/0.445
4u0mATPCyclic GMP-AMP synthase/0.445
5a3cNADSIR2 family protein/0.445
1g63FMNEpidermin decarboxylase4.1.10.444
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.444
1k6cMK1Gag-Pol polyprotein3.4.23.160.444
1l3iSAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)/0.444
1n83CLRNuclear receptor ROR-alpha/0.444
1psa0ZLPepsin A3.4.23.10.444
2e8qSAHDiphthine synthase/0.444
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.444
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.444
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
2xa4AZ5Tyrosine-protein kinase JAK2/0.444
2ylzFADPhenylacetone monooxygenase1.14.13.920.444
3ai3NDPNADPH-sorbose reductase/0.444
3b895GP16S rRNA methylase/0.444
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.444
3gbuATPUncharacterized sugar kinase PH14592.7.10.444
3hwrNDP2-dehydropantoate 2-reductase/0.444
3iaeD7KBenzaldehyde lyase/0.444
3icsADPCoenzyme A disulfide reductase/0.444
3ipkPMSSurface protein adhesin/0.444
3lqsPSZD-alanine aminotransferase2.6.1.210.444
4d03FADPhenylacetone monooxygenase1.14.13.920.444
4djw0KPBeta-secretase 13.4.23.460.444
4g7gVFVLanosterol 14-alpha-demethylase/0.444
4jldADPAdenylate kinase/0.444
4z875GPInosine-5'-monophosphate dehydrogenase/0.444
5bsgNAPPyrroline-5-carboxylate reductase/0.444
1drfFOLDihydrofolate reductase1.5.1.30.443
1fwkADPHomoserine kinase2.7.1.390.443
1honGNHAdenylosuccinate synthetase/0.443
1kceCB3Thymidylate synthase/0.443
1mxiSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.443
1nvtNAPShikimate dehydrogenase (NADP(+))/0.443
1txtCAAHMG-CoA synthase/0.443
1ykdCMPAdenylate cyclase/0.443
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.443
2cjiGSKCoagulation factor X3.4.21.60.443
2d4vNADIsocitrate dehydrogenase [NADP]/0.443
2dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.443
2f3rG5PGuanylate kinase2.7.4.80.443
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2fieA74Fructose-1,6-bisphosphatase 13.1.3.110.443
2gvdFKPAdenylate cyclase type 2/0.443
2gvdFKPAdenylate cyclase type 5/0.443
2oegUPGUDP-glucose pyrophosphorylase/0.443
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.443
2qboCAMCamphor 5-monooxygenase1.14.15.10.443
2xbxRR8Coagulation factor X3.4.21.60.443
2zjmF1MBeta-secretase 13.4.23.460.443
3ai2NDPNADPH-sorbose reductase/0.443
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.443
3lxiCAMCytochrome P450/0.443
3mgdACOPredicted acetyltransferase/0.443
3n4kSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.443
3pldF90Endothiapepsin3.4.23.220.443
4an4DUDPutative glycosyl transferase/0.443
4b42942Glucose-1-phosphate thymidylyltransferase/0.443
4bakM67Prothrombin3.4.21.50.443
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.443
4fdaNAP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.443
4gah0ETAcyl-coenzyme A thioesterase THEM43.1.2.20.443
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4jicFMNGTN Reductase/0.443
4lhvGDPRas-related protein Rab-8A/0.443
4lxk1YTBeta-secretase 13.4.23.460.443
4rcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.443
4x5iFOLDihydrofolate reductase1.5.1.30.443
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.443
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.443
1a4rGNHCell division control protein 42 homolog/0.442
1dg8NDPDihydrofolate reductase1.5.1.30.442
1iy8NADLevodione reductase/0.442
1me6IVSPlasmepsin-23.4.23.390.442
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.442
1osvCHCBile acid receptor/0.442
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.442
1sdmADPKinesin heavy chain-like protein/0.442
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.442
2a92NAIL-lactate dehydrogenase/0.442
2ath3EAPeroxisome proliferator-activated receptor gamma/0.442
2iviACWIsopenicillin N synthase1.21.3.10.442
2yx6ADPUncharacterized protein/0.442
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3anlSYC1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.442
3arnMSJDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial3.6.1.230.442
3atyFMNProstaglandin F2a synthase/0.442
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3frqERYErythromycin resistance repressor protein/0.442
3gobHXXDdmC/0.442
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.442
3pl8FADPyranose 2-oxidase/0.442
3pwwROCEndothiapepsin3.4.23.220.442
3w77FMNFMN-dependent NADH-azoreductase/0.442
3w8eNAD3-hydroxybutyrate dehydrogenase/0.442
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.442
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.442
4euc0RQSuccinyl-CoA:acetate CoA-transferase/0.442
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.442
4ha9NDP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase1.1.1.3020.442
4ikeADPAdenylate kinase/0.442
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.442
4jc51K5Stimulator of interferon genes protein/0.442
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.442
4lj9ACPChaperone protein ClpB/0.442
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.442
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.442
5cyoGDPSeptin-9/0.442
1bim0QBRenin3.4.23.150.441
1f5nGNPGuanylate-binding protein 1/0.441
1f8sFADL-amino-acid oxidase1.4.3.20.441
1l5k1RBNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.441
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.441
1mvsDTMDihydrofolate reductase1.5.1.30.441
1vsvNADGlyceraldehyde-3-phosphate dehydrogenase/0.441
2aa3AP0L-lactate dehydrogenase/0.441
2bgmNAJSecoisolariciresinol dehydrogenase1.1.1.3310.441
2bi4NADLactaldehyde reductase1.1.1.770.441
2dxwSAHDiphthine synthase/0.441
2eh2SAHDiphthine synthase/0.441
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.441
2fznFADBifunctional protein PutA1.5.5.20.441
2gv8NDPThiol-specific monooxygenase1.14.130.441
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.441
2pciSAHDiphthine synthase/0.441
2vcmM11Isopenicillin N synthase1.21.3.10.441
2w3bNDPDihydrofolate reductase1.5.1.30.441
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3e5rNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.441
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.441
3fwfCAMCamphor 5-monooxygenase1.14.15.10.441
3h3t16HCollagen type IV alpha-3-binding protein/0.441
3hlwCE3Beta-lactamase/0.441
3ixp834Ecdysone receptor/0.441
3ld6BCDLanosterol 14-alpha demethylase1.14.13.700.441
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.441
3ou2SAHSAM-dependent methyltransferase/0.441
3p2oNADBifunctional protein FolD/0.441
3qj0QI3Botulinum neurotoxin type A3.4.24.690.441
4djaFAD(6-4) photolyase/0.441
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.441
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
5a0112VO-glycosyltransferase/0.441
5jjrSAHGenome polyprotein/0.441
1e1kFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.440
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.440
1gj5130Prothrombin3.4.21.50.440
1jhaAAMNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.440
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.440
1qiqACCIsopenicillin N synthase1.21.3.10.440
1vbiNADMalate/L-lactate dehydrogenase family protein/0.440
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
1zemNADXylitol dehydrogenase/0.440
2b9yFADPutative aminooxidase/0.440
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.440
2bvs2CEProthrombin3.4.21.50.440
2dv5SAHDiphthine synthase/0.440
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.440
2p5fSAHDiphthine synthase/0.440
2pksG44Prothrombin3.4.21.50.440
2qtvGNPSmall COPII coat GTPase SAR13.6.50.440
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.440
2yy8MTAtRNA (cytidine(56)-2'-O)-methyltransferase/0.440
3clsFADElectron transfer flavoprotein subunit alpha/0.440
3drcMTXDihydrofolate reductase1.5.1.30.440
3ed1GA3Gibberellin receptor GID1/0.440
3gnwXNCGenome polyprotein2.7.7.480.440
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.440
3p82FMNPentaerythritol tetranitrate reductase/0.440
3r83Z14Cyclin-dependent kinase 22.7.11.220.440
3t3r9PLCytochrome P450 2A61.14.130.440
3w2mZRODihydroorotate dehydrogenase (fumarate)1.3.98.10.440
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.440
4ewo996Beta-secretase 13.4.23.460.440
4gapNADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.440
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.440
4m4922YL-lactate dehydrogenase A chain1.1.1.270.440
4z0hNADGlyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic1.2.1.120.440
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
4ea30NNNociceptin receptor/0.440