sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3t7v | SAM | 3-methylornithine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3t7v | SAM | 3-methylornithine synthase | / | 1.000 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.460 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.458 | |
| 3pju | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.456 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.456 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.454 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.452 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.451 | |
| 1szc | CNA | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.450 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.448 | |
| 3pjt | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.447 | |
| 4wcx | SAM | Biotin and thiamin synthesis associated | / | 0.447 | |
| 2oat | PFM | Ornithine aminotransferase, mitochondrial | 2.6.1.13 | 0.446 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2ejz | SAH | Diphthine synthase | / | 0.444 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.444 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 |