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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3t59FADSulfhydryl oxidase 11.8.3.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3t59FADSulfhydryl oxidase 11.8.3.21.000
4p2lFADSulfhydryl oxidase 11.8.3.20.594
3t58FADSulfhydryl oxidase 11.8.3.20.529
3llkFADSulfhydryl oxidase 11.8.3.20.486
3lliFADSulfhydryl oxidase 11.8.3.20.445